Inflammation and Immune Response Quiz

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Questions and Answers

What is the main purpose of inflammation?

To initiate disease progression
To cause injury to normal tissues
To eliminate the initial cause of injury and necrotic cells/tissues (correct)
To prevent repair process

What are the learning objectives related to inflammatory cells and mediators?

Discuss types of heart diseases
Discuss methods of brain imaging
Discuss causes of lung cancer
Discuss steps and cardinal signs of inflammation (correct)

What is the purpose of the host response in inflammation?

To eliminate the initial cause of injury (correct)
To cause injury to normal tissues
To prevent repair process
To induce necrosis in healthy cells

What is the intended outcome of inflammation?

To initiate the repair process (D) Signup and view all the answers

What does inflammation do to normal tissues?

It can injure normal tissues (A) Signup and view all the answers

What are the cellular and vascular events involved in acute inflammatory cells?

Chemical mediators (B) Signup and view all the answers

What is the primary goal of the repair process initiated by inflammation?

To restore normal tissue function (B) Signup and view all the answers

What is the purpose of discussing diseases with mutations affecting inflammatory cells/mediators?

To understand the impact of mutations on inflammatory responses (A) Signup and view all the answers

What are the morphologic patterns described in relation to inflammation?

Acute and chronic inflammation (B) Signup and view all the answers

What are the components involved in regeneration and repair of tissues?

Extracellular matrix components (A) Signup and view all the answers

What is the process of repair involving connective tissue deposition?

Repair by connective tissue deposition (D) Signup and view all the answers

What is the overall purpose of the host response in inflammation?

To protect the body from injury and initiate repair (B) Signup and view all the answers

What are the cardinal signs of inflammation?

Heat, redness, swelling, pain, and loss of function (D) Signup and view all the answers

Which cells are involved in chronic inflammation?

Lymphocytes, plasma cells, and macrophages (B) Signup and view all the answers

Which type of immunity is the acute inflammatory response part of?

Innate immunity (B) Signup and view all the answers

What are the mediators of the acute inflammatory response?

Neutrophils, endothelial cells, mast cells, eosinophils, platelets, histamine, cytokines, arachidonic acid metabolites, and complement (C) Signup and view all the answers

What is the role of neutrophils in acute inflammation?

Phagocytose microorganisms and produce reactive oxygen species (D) Signup and view all the answers

What do platelets promote in the inflammatory response?

Clot formation and contain inflammatory mediators (A) Signup and view all the answers

What is the function of eosinophils in inflammation?

Defend against parasitic infections and are involved in allergic reactions and inflammatory reactions (C) Signup and view all the answers

What do mast cells release in response to trauma or IgE receptor cross-linking?

Preformed histamine granules, and synthesize lipid mediators and cytokines (D) Signup and view all the answers

What distinguishes between acute and chronic inflammatory responses according to Robbins Pathology?

Robbins Pathology distinguishes between acute and chronic inflammatory responses (B) Signup and view all the answers

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Study Notes

Inflammation and Immune Response Overview

Inflammation is the body’s response to injury, infection, insult, or autoimmunity, involving a sequence of events.
The steps of the inflammatory response include recognition, leukocyte recruitment, removal of the inciting agent, regulation, and resolution.
Cardinal signs of inflammation include heat, redness, swelling, pain, and loss of function.
Acute inflammation involves immediate, nonspecific responses with neutrophils and macrophages, while chronic inflammation is a delayed, more specific response involving lymphocytes, plasma cells, and macrophages.
The acute inflammatory response is part of innate immunity and involves components like neutrophils, macrophages, and complement, with limited diversity and a rapid, nonspecific response.
Chronic inflammatory response is part of adaptive immunity, involving T and B lymphocytes, antibodies, and a highly specific, memory response to infection.
Robbins Pathology distinguishes between acute and chronic inflammatory responses.
Mediators of the acute inflammatory response include neutrophils, endothelial cells, mast cells, eosinophils, platelets, histamine, cytokines, arachidonic acid metabolites, and complement.
Neutrophils are central to acute inflammation, with the ability to phagocytose microorganisms and produce reactive oxygen species.
Platelets promote clot formation and contain inflammatory mediators.
Eosinophils defend against parasitic infections and are involved in allergic reactions and inflammatory reactions.
Mast cells, found in tissues, recognize microbial products, release preformed histamine granules, and synthesize lipid mediators and cytokines in response to trauma or IgE receptor cross-linking.