Inflammation: Acute & Chronic

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51 Questions

Which of the following is a common cause of inflammation?

Viral infections

What is the result of viral infection on individual cells?

Intracellular multiplication leading to cell death

Which microbes release specific toxins that contribute to inflammation?

Bacteria

What are the characteristic symptoms of inflammation?

Redness, swelling, heat, pain, loss of function

What is a characteristic of acute inflammation?

Vascular changes including vasodilation and increased vascular permeability

Which stimuli can cause acute inflammation?

Infections, tissue damage, immune reactions, and chemical mediators

What can cause tissue necrosis and inflammation?

Infections such as bacterial, viral, fungal, parasitic, and microbial toxins

Which factor can cause vascular leakage in acute inflammation?

Chemical mediators like histamine and cytokines

What is a common cause of chronic inflammation?

Persistent injury or infection

What is a notable feature of chronic inflammation?

Tissue destruction, repair, and fibrosis

Which diseases may involve chronic inflammation?

Tuberculosis, pulmonary silicosis, multiple sclerosis

What type of agents can cause tissue damage and vascular leakage?

Physical agents like ischemia and trauma

What may trigger acute inflammation?

Immune reactions including hypersensitivity reactions

What factor can cause vascular leakage in chronic inflammation?

Chemical mediators like cytokines

What conditions tend to occur under chronic inflammation?

Persistent organisms and prolonged exposure to toxins

What is one way viruses cause cell death?

By multiplying inside cells

What can bacterial toxins cause?

Hypersensitivity reaction

How can physical or chemical agents cause tissue damage and inflammation?

Through direct contact or radiation

What leads to an acute inflammatory response?

Tissue necrosis

What is the function of fever in response to inflammation?

To improve the efficiency of leukocyte killing and impair the replication of some invading organisms.

What can cause tissue damage from inflammation?

Viral and bacterial infections

What are potential long-term health consequences of systemic impact from inflammation?

Chronic inflammation, scarring, and tissue fibrosis

What is the role of leukocytosis in inflammation?

To increase circulating white blood cells

How does tissue necrosis contribute to inflammation?

By leading to an acute inflammatory response

What are local effects of inflammation?

Tissue damage and acute inflammatory response

How do bacteria contribute to tissue damage?

By producing specific toxins damaging tissues

Which of the following microbes can contribute to inflammation by causing the death of individual cells through intracellular multiplication?

Viruses

What is the mechanism by which bacteria can contribute to inflammation?

Release of endotoxins

What are the common causes of inflammation?

Bacteria and microbial infections

What are the typical characteristics of inflammation in living tissue?

Redness, swelling, heat, pain, and loss of function

How do viruses cause cell death?

By multiplying inside cells or inhibiting their function

What can bacterial toxins cause?

Hypersensitivity reaction damaging tissues

How can physical or chemical agents cause tissue damage and inflammation?

Through direct contact or radiation exposure

What leads to an acute inflammatory response?

Tissue necrosis

What is the function of fever in response to inflammation?

To improve the efficiency of leukocyte killing and impair the replication of some invading organisms

What are potential long-term health consequences of systemic impact from inflammation?

Chronic inflammation and scarring

What can cause tissue damage from inflammation?

Viral and bacterial infections, physical trauma, chemical or radiation exposure

What is a characteristic symptom of inflammation?

Fever

What may trigger acute inflammation?

Physical trauma

What is a common cause of chronic inflammation?

Persistent irritants

How does tissue necrosis contribute to inflammation?

It leads to an acute inflammatory response.

Which of the following can trigger acute inflammation?

Infections

What is a characteristic of chronic inflammation?

Prolonged duration and tissue destruction

Which chemical mediators can contribute to vascular leakage in acute inflammation?

Histamine and cytokines

What type of agents can cause tissue damage and vascular leakage?

Physical agents

Which diseases may involve chronic inflammation?

Rheumatoid arthritis

What are the stimuli for acute inflammation?

Infections, tissue damage, immune reactions, chemical mediators

How do immune reactions contribute to acute inflammation?

By triggering hypersensitivity reactions

What can cause chronic inflammation?

Prolonged exposure to toxins

What role do physical agents play in causing tissue damage?

They contribute to vascular changes.

Which of the following is a characteristic of chronic inflammation?

Prolonged persistence with fibrosis

Study Notes

  • Viruses cause cell death through multiplication inside cells or by inhibiting their function, leading to cell death or cell rupture.

  • Bacteria produce specific toxins that can cause a hypersensitivity reaction, an inappropriate immune response that damages tissues.

  • Physical or chemical agents, such as irritants or corrosive chemicals, can cause tissue damage and inflammation through direct contact or radiation.

  • Tissue necrosis, or cell death due to lack of oxygen or nutrients, leads to an acute inflammatory response.

  • Inflammation can have both local and systemic effects, including fever, malaise, and leukocytosis (an increase in circulating white blood cells).

  • Fever is a common response to inflammation, and its function is to improve the efficiency of leukocyte killing and impair the replication of some invading organisms.

  • Inflammation can occur as a result of various causes, including viral and bacterial infections, physical trauma, and chemical or radiation exposure.

  • Tissue damage from inflammation can lead to further complications, such as chronic inflammation, scarring, and tissue fibrosis.

  • Inflammation can also have a systemic impact on the body, leading to symptoms such as fever, malaise, and fatigue, as well as potential long-term health consequences.

  • Acute inflammation is characterized by vascular changes, including vasodilation and increased vascular permeability, leading to edema and white blood cell recruitment.

  • The stimuli for acute inflammation include infections, tissue damage, immune reactions, and chemical mediators.

  • Infections, such as bacterial, viral, fungal, parasitic, and microbial toxins, can cause tissue necrosis and inflammation.

  • Immune reactions, including hypersensitivity reactions, can also trigger acute inflammation.

  • Chemical mediators, such as histamine and cytokines, can cause vascular leakage and further contribute to inflammation.

  • Physical agents, like ischemia, trauma, and thermal injury, can cause tissue damage and vascular leakage.

  • Foreign bodies, like splinters, dirt, and sutures, can also trigger an inflammatory response.

  • In chronic inflammation, the inflammatory response persists for a long duration and results in tissue destruction, repair, and fibrosis.

  • Chronic inflammation can be caused by persistent injury or infection, prolonged exposure to toxins, and autoimmune diseases.

  • Chronic inflammation is a common component in many diseases, including ulcers, tuberculosis, pulmonary silicosis, and autoimmune diseases like rheumatoid arthritis, lupus erythematosus, and multiple sclerosis.

  • Chronic inflammation tends to occur under certain conditions, including persistent organisms, repeated bouts of acute inflammation, and prolonged exposure to toxins.

Learn about the response of living tissue to injury, including redness, swelling, heat, pain, and loss of function. Understand the causes of inflammation, including microbial infections and tissue injury.

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