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Questions and Answers
What is the primary advantage of capsules as a dosage form?
What is the primary advantage of capsules as a dosage form?
- They require minimal excipient and high pressure to compact the material
- They provide a rough, easily swallowed shell for drugs
- They offer a smooth, slippery, and tasteless shell for drugs (correct)
- They are economically produced in small quantities
What is the composition of the shell of soft gelatin capsules?
What is the composition of the shell of soft gelatin capsules?
- Flexible rubber compound
- Rigid plastic material
- Hardened sugar coating
- Plasticized gelatin film (correct)
Why are soft gelatin capsules filled, formed, and sealed in a single operation?
Why are soft gelatin capsules filled, formed, and sealed in a single operation?
- To reduce production costs
- To simplify the manufacturing process (correct)
- To improve the quality of the capsule shell
- To prevent solubilization of the shell material
How are soft gelatin capsules different from hard gelatin capsules?
How are soft gelatin capsules different from hard gelatin capsules?
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Which type of drug is particularly benefited by the use of capsules as a dosage form?
Which type of drug is particularly benefited by the use of capsules as a dosage form?
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Study Notes
Industrial Pharmacy: Capsules
- Capsules are a type of solid dosage form that encloses a drug substance within a hard or soft soluble shell.
- The shell is generally formed from gelatin.
- The entire unit, including the shell and the drug substance, is considered a single dosage form.
- Capsules can be classified into two categories: hard and soft capsules.
- Hard capsules are typically made from gelatin and are available in various sizes and shapes.
- Soft capsules, also known as softgels, are formed from a soft gelatin shell and are often used to encapsulate liquids or semi-solids.
- The shell of a capsule is usually made up of two parts: a cap and a body.
- The cap is the smaller of the two parts and is sealed to the body to form a single unit.
- The body of the capsule is the larger part that contains the drug substance.
- Capsules are a popular dosage form due to their ease of use, convenience, and ability to mask unpleasant tastes or odors.
- The manufacturing process of capsules typically involves several stages, including filling, closing, and inspection.
- Quality control measures are essential to ensure the quality and purity of the final product.
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