Podcast
Questions and Answers
What should be given the most weight when making decisions about new dental products?
What should be given the most weight when making decisions about new dental products?
- In vitro evidence
- Evidence from the scientific literature
- Anecdotal evidence from dental professionals
- Clinical evidence (correct)
What does the vertical location of each layer in the evidence pyramid indicate?
What does the vertical location of each layer in the evidence pyramid indicate?
- The complexity of the research methods used
- The relative weight that should be applied to that type of research (correct)
- The amount of that type of evidence available
- The chronological order in which different types of research are conducted
What does the width of each layer in the evidence pyramid indicate?
What does the width of each layer in the evidence pyramid indicate?
- The level of difficulty in conducting that type of research
- The cost associated with that type of research
- The relative weight that should be applied to that type of research
- The relative amount of that type of evidence available in the scientific literature (correct)
Despite its drawbacks, what role does in vitro research play in the development of dental products?
Despite its drawbacks, what role does in vitro research play in the development of dental products?
Which type of evidence is considered the most reliable for determining the clinical performance of dental products?
Which type of evidence is considered the most reliable for determining the clinical performance of dental products?
What are the two main purposes of in vitro testing according to the passage?
What are the two main purposes of in vitro testing according to the passage?
What type of in vitro test was found to predict marginal fracture or 'ditching' in dental amalgam fillings?
What type of in vitro test was found to predict marginal fracture or 'ditching' in dental amalgam fillings?
What characteristic of the microstructure was associated with more ditching-resistant amalgams according to the passage?
What characteristic of the microstructure was associated with more ditching-resistant amalgams according to the passage?
Which of the following is NOT mentioned in the passage as a measure of a product's efficacy?
Which of the following is NOT mentioned in the passage as a measure of a product's efficacy?
According to the passage, what is necessary before conducting clinical studies?
According to the passage, what is necessary before conducting clinical studies?
What is the purpose of incubating cells with the materials in cell culture wells?
What is the purpose of incubating cells with the materials in cell culture wells?
Why is it important to use dentin as a barrier in the Dentin Barrier Test?
Why is it important to use dentin as a barrier in the Dentin Barrier Test?
Why might composites appear more cytotoxic in vitro than they would be clinically?
Why might composites appear more cytotoxic in vitro than they would be clinically?
What is the likely reason for a rash developing on hands when handling methacrylate denture base and monomer?
What is the likely reason for a rash developing on hands when handling methacrylate denture base and monomer?
How long should cells be incubated with the materials?
How long should cells be incubated with the materials?
What should be observed under phase-contrast microscopy after incubating cells with the materials?
What should be observed under phase-contrast microscopy after incubating cells with the materials?
What is the primary factor contributing to the clinical failure of composite restorations?
What is the primary factor contributing to the clinical failure of composite restorations?
What role do in vitro tests play in the early development stages of new dental materials?
What role do in vitro tests play in the early development stages of new dental materials?
What is the trade-off between clinical relevance and precision in testing methods for dental materials?
What is the trade-off between clinical relevance and precision in testing methods for dental materials?
In the case of dentin bond-strength evaluation, which testing method is described as having more clinical relevance?
In the case of dentin bond-strength evaluation, which testing method is described as having more clinical relevance?
What factors contribute to the variability in testing actual dental crowns removed from real teeth?
What factors contribute to the variability in testing actual dental crowns removed from real teeth?
Based on the information provided, which statement is true regarding the evaluation of dental materials?
Based on the information provided, which statement is true regarding the evaluation of dental materials?
What is the purpose of the MTT assay?
What is the purpose of the MTT assay?
What is the principle behind the MTT assay?
What is the principle behind the MTT assay?
What is the purpose of the Ames test?
What is the purpose of the Ames test?
What is the difference between genotoxicity and mutagenicity?
What is the difference between genotoxicity and mutagenicity?
Which statement is true about the Ames test?
Which statement is true about the Ames test?
What is the significance of the ANSI/ADA specification No. 41, 1982 addendum?
What is the significance of the ANSI/ADA specification No. 41, 1982 addendum?
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