Importance of Keratin to Human Tissues
16 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the main function of keratins in epithelial cells?

  • Regulate cell division
  • Provide energy to the cells
  • Transport molecules between cells
  • Impart mechanical strength (correct)
  • Which accessory protein bundles keratin to give skin toughness?

  • Actinin
  • Keratonetein (correct)
  • Myosin
  • Laminin
  • What type of diseases can mutations in keratins predispose individuals to?

  • Respiratory diseases
  • Brain disorders
  • Autoimmune diseases
  • Dry skin diseases (correct)
  • In which disease do individuals experience skin blisters in response to slight mechanical stress?

    <p>Epidermolysis bullosa</p> Signup and view all the answers

    Which disorder is characterized by the disorganization of the keratin filament cytoskeleton due to mechanical stress?

    <p>Epidermolysis bullosa</p> Signup and view all the answers

    What is the role of neurofilaments (NFs) in determining axonal diameter?

    <p>Incorporating subunits along the length of the axon</p> Signup and view all the answers

    Which disorder can be caused by mutations in the plectin protein?

    <p>Epidermolysis bullosa</p> Signup and view all the answers

    What is the main function of Plakins in the cytoskeleton?

    <p>Linking intermediate filaments (IFs) to actin and microtubules</p> Signup and view all the answers

    What determines the speed of transmission in neurons?

    <p>The level of neurofilament expression</p> Signup and view all the answers

    Which protein is mentioned in association with both epidermolysis bullosa and neurodegeneration?

    <p>Keratin</p> Signup and view all the answers

    What is the diameter range of Arp1 filaments, which are similar in size to actin filaments?

    <p>8-11 nm</p> Signup and view all the answers

    Why are intermediate filaments (IFs) prominent in the cytoplasm of cells subject to mechanical stress?

    <p>IFs provide structural support and tensile strength to withstand mechanical stress.</p> Signup and view all the answers

    How are intermediate filaments (IFs) related to nuclear lamins?

    <p>Nuclear lamins are a type of intermediate filament found in the nucleus.</p> Signup and view all the answers

    What is the main feature of the conserved α-helical domain in all intermediate filaments (IFs) that allows them to form extended coiled-coil structures?

    <p>The α-helical domain allows IFs to form parallel dimers that associate into anti-parallel staggered tetramers.</p> Signup and view all the answers

    What is the key feature that makes keratins the most diverse of the intermediate filament (IF) proteins?

    <p>Keratins are the only IFs that have a heterodimeric filament subunit, with one acidic and one neutral/basic protein.</p> Signup and view all the answers

    What is the main function of the anti-parallel staggered tetramers formed by intermediate filaments (IFs)?

    <p>The tetramers provide the tensile strength and ability to be stretched to 3 times their usual length.</p> Signup and view all the answers

    More Like This

    Fc12B epithelium 2 oct
    14 questions
    Keratins in Epithelial Tissue
    12 questions
    Biology: Keratin and Healthy Nails
    8 questions
    Queratinas en Humanos
    48 questions

    Queratinas en Humanos

    FlashyRapture1275 avatar
    FlashyRapture1275
    Use Quizgecko on...
    Browser
    Browser