Podcast
Questions and Answers
How can mutations inside the coding sequence impact gene expression?
How can mutations inside the coding sequence impact gene expression?
- By inducing changes in regulatory sequences
- By impacting gene expression
- By altering the abundance of mRNA
- By resulting in structurally abnormal proteins (correct)
What can mutations in regulatory elements alter?
What can mutations in regulatory elements alter?
- The abundance of the mRNA (correct)
- The structure of the protein
- The location of the gene
- The size of the gene
Where do most random breakpoints lie?
Where do most random breakpoints lie?
- In introns
- In intergenic DNA (correct)
- In regulatory elements
- In exons
What is necessary to form a biologically active protein?
What is necessary to form a biologically active protein?
What can mutations at the transcriptional level induce?
What can mutations at the transcriptional level induce?
What can mutations that do not result in amino acid substitution affect?
What can mutations that do not result in amino acid substitution affect?
Where do most random breakpoints lie?
Where do most random breakpoints lie?
What is necessary to form a biologically active protein?
What is necessary to form a biologically active protein?
How can mutations inside the coding sequence impact gene expression?
How can mutations inside the coding sequence impact gene expression?
What can mutations in regulatory elements alter?
What can mutations in regulatory elements alter?
Flashcards
Coding sequence mutations
Coding sequence mutations
Changes within the DNA sequence that codes for a protein. These mutations can lead to the production of structurally abnormal proteins.
Regulatory element mutations
Regulatory element mutations
Changes in DNA sequences that control gene expression. They can affect how much mRNA is produced from a gene.
Random breakpoints
Random breakpoints
Locations where DNA breaks occur randomly. Most commonly found outside of coding sequences.
Biologically active protein formation
Biologically active protein formation
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Mutations in regulatory elements
Mutations in regulatory elements
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Silent mutations
Silent mutations
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Most random breakpoints
Most random breakpoints
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Biologically active protein formation
Biologically active protein formation
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Coding sequence mutations
Coding sequence mutations
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Mutations in regulatory elements
Mutations in regulatory elements
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