Impact of Mutations on Gene Expression
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Questions and Answers

How can mutations inside the coding sequence impact gene expression?

  • By inducing changes in regulatory sequences
  • By impacting gene expression
  • By altering the abundance of mRNA
  • By resulting in structurally abnormal proteins (correct)
  • What can mutations in regulatory elements alter?

  • The abundance of the mRNA (correct)
  • The structure of the protein
  • The location of the gene
  • The size of the gene
  • Where do most random breakpoints lie?

  • In introns
  • In intergenic DNA (correct)
  • In regulatory elements
  • In exons
  • What is necessary to form a biologically active protein?

    <p>Transcription, mRNA processing, and translation</p> Signup and view all the answers

    What can mutations at the transcriptional level induce?

    <p>Changes in regulatory sequences</p> Signup and view all the answers

    What can mutations that do not result in amino acid substitution affect?

    <p>Transcription, RNA processing, translation, or protein stability</p> Signup and view all the answers

    Where do most random breakpoints lie?

    <p>In intergenic DNA or in introns</p> Signup and view all the answers

    What is necessary to form a biologically active protein?

    <p>Transcription from gene to mRNA and then translation into polypeptide</p> Signup and view all the answers

    How can mutations inside the coding sequence impact gene expression?

    <p>By impacting gene expression at the transcriptional level</p> Signup and view all the answers

    What can mutations in regulatory elements alter?

    <p>The abundance (expression level) of the mRNA or the time or cell type in which the gene is expressed</p> Signup and view all the answers

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