Unit 2 Chapter 17 Obesity and Weight Management
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Questions and Answers

What is the global obesity prevalence based on body mass index (BMI) thresholds?

  • 30 kg/m2 for overweight, 35 kg/m2 or greater for obesity
  • 20 kg/m2 for overweight, 25 kg/m2 or greater for obesity
  • 25 kg/m2 for overweight, 30 kg/m2 or greater for obesity (correct)
  • 15 kg/m2 for overweight, 20 kg/m2 or greater for obesity

What was the global age-standardized BMI in men in 2014?

  • 26.5 kg/m2
  • 28.1 kg/m2
  • 24.2 kg/m2 (correct)
  • 21.7 kg/m2

Which group has the lowest obesity rates among adults according to the text?

  • Non-Hispanic blacks
  • Hispanics
  • Non-Hispanic Asians (correct)
  • Non-Hispanic white adults

What was the estimated crude prevalence of adults with obesity in the United States according to the 2015 to 2016 NHANES data?

<p>39.8% (D)</p> Signup and view all the answers

Which group of women has the highest obesity prevalence?

<p>Non-Hispanic black women (C)</p> Signup and view all the answers

How is food insecurity associated with obesity rates in US women?

<p>It is modestly associated with higher obesity rates in non-white women (C)</p> Signup and view all the answers

What is the relationship between level of education and obesity or overweight?

<p>Level of education is inversely related to obesity and overweight (C)</p> Signup and view all the answers

In immigrant adults, how do obesity rates change with time lived in the United States?

<p>Obesity rates increase with time lived in the United States (A)</p> Signup and view all the answers

Which group of immigrants has a three-times-higher odds ratio of being overweight after 15 years in the United States?

<p>Immigrants from Europe (D)</p> Signup and view all the answers

What is BMI a proxy measure of?

<p>Body fatness (D)</p> Signup and view all the answers

What is a reliable measure of adiposity that is used in research settings?

<p>Dual-energy X-ray absorptiometry (DXA) (A)</p> Signup and view all the answers

Why is bioimpedance analysis (BIA) not recommended for routine clinical use in individuals with obesity?

<p>It does not add more information than BMI and waist circumference (C)</p> Signup and view all the answers

What is the theoretical weight gain per year from an extra 100 kcal/day intake or not expended?

<p>4.5 kg (10 pounds) (B)</p> Signup and view all the answers

What are the two commonalities in the causes of obesity mentioned?

<p>Increased energy intake and reduced energy expenditure (C)</p> Signup and view all the answers

Which part of the brain is mainly responsible for driving energy expenditure?

<p>Hypothalamus (A)</p> Signup and view all the answers

Which type of adipose tissue is linked to more deleterious health consequences?

<p>Intra-abdominal visceral fat depots (A)</p> Signup and view all the answers

What do insulin and leptin signal in terms of food and adipose tissue?

<p>Adequacy (A)</p> Signup and view all the answers

Which method is considered noninvasive, portable, safe, and inexpensive for predicting body fat?

<p>Bioimpedance analysis (BIA) (B)</p> Signup and view all the answers

Which neurons promote hunger and increased food intake?

<p>Agouti-related protein/neuropeptide Y (AgRP/NPY) neurons (A)</p> Signup and view all the answers

What does an obesogenic environment primarily promote?

<p>Excess calorie intake (A)</p> Signup and view all the answers

What is the main aspect that activates the hedonic pathway in relation to food consumption?

<p>Food's hedonic qualities (A)</p> Signup and view all the answers

Why are guidelines for treatment of overweight and obesity hesitant to recommend using bioimpedance analysis (BIA)?

<p>It adds no more information than BMI and waist circumference (D)</p> Signup and view all the answers

What inhibits activities that use energy for conservation purposes?

<p>Agouti-related protein/neuropeptide Y (AgRP/NPY) neurons (D)</p> Signup and view all the answers

'Excess body weight and obesity result when which forces are greater than the opposing forces?'

<p>Energy intake and energy expenditure (D)</p> Signup and view all the answers

What can induce hyperphagia by suppressing satiety signaling and increasing hunger?

<p>Lesions in the hypothalamus (C)</p> Signup and view all the answers

Which of the following factors affects individual appetite, satiety, and meal size?

<p>Neuroendocrine factors, adipocyte size, and number, gut factors, food availability, society norms, nutrient interactions. (B)</p> Signup and view all the answers

What is associated with rapid weight gain, uncontrolled eating, and hyperinsulinemia?

<p>Hypothalamic OB (C)</p> Signup and view all the answers

Which hormone is mentioned as the central controller of energy balance in the text?

<p>Insulin (A)</p> Signup and view all the answers

What are considered reliable measures of adiposity used in research settings but not practical in routine clinical use?

<p>Hydrodensitometry (underwater weighing) and air displacement plethysmography. (D)</p> Signup and view all the answers

What is the main cause of overactivity of the hedonic pathway in the brain?

<p>Hyperinsulinemia (C)</p> Signup and view all the answers

Which factor can lead to reduced energy output according to the text?

<p>Chemically induced lesions in the hypothalamus (A)</p> Signup and view all the answers

What signals adequacy of both food intake and adipose tissue status?

<p>Insulin and leptin (A)</p> Signup and view all the answers

What is the primary function of pancreatic β cells?

<p>Secrete insulin (C)</p> Signup and view all the answers

In a fasted state, what is released from pancreatic α cells to maintain euglycemia?

<p>Glucagon (D)</p> Signup and view all the answers

What is the primary role of leptin in the body?

<p>Signal satiety and control meal size (B)</p> Signup and view all the answers

Which hormone acts as a long-term 'lipostat', communicating the amount of stored body fat to the hypothalamus?

<p>Leptin (B)</p> Signup and view all the answers

What is the primary function of glucagon-like peptide 1 (GLP-1) in the body?

<p>Regulate glucose by altering insulin activity (D)</p> Signup and view all the answers

Which hormone is secreted by adipocytes and has beneficial effects on glycemic control and insulin sensitivity?

<p>Adiponectin (A)</p> Signup and view all the answers

What does visceral adipose tissue secrete less of compared to subcutaneous depots?

<p>Adiponectin (A)</p> Signup and view all the answers

'Central leptin and insulin resistance' in obesity is primarily due to what factor?

<p>'Resistive' leptin and insulin receptors (A)</p> Signup and view all the answers

What effect does decreased pancreatic insulin secretion have on the use of stored fat?

<p>Increases use of stored fat (A)</p> Signup and view all the answers

How do adrenal epinephrine and norepinephrine promote the utilization of stored fat?

<p>Promote use of stored fat (C)</p> Signup and view all the answers

What is the primary function of cholecystokinin?

<p>Stimulate gallbladder contraction (D)</p> Signup and view all the answers

What is the main mechanism disrupted in individuals with MC4R mutations?

<p>Satiety signaling (A)</p> Signup and view all the answers

Which gene is recognized as the strongest obesity signaling gene?

<p>FTO gene (C)</p> Signup and view all the answers

What is the most common type of obesity according to the text?

<p>Polygenic obesity (C)</p> Signup and view all the answers

Which syndrome obesities are mentioned in the text as the two most common?

<p>Prader-Willi and Bardet-Biedl (A)</p> Signup and view all the answers

What is a significant risk factor for overweight or obesity in toddlers?

<p>Excessive maternal weight during pregnancy (B)</p> Signup and view all the answers

How is breastfeeding related to childhood obesity risk?

<p>Decreases childhood obesity risk (A)</p> Signup and view all the answers

What effect does timing of solid food introduction have on weight gain based on feeding method?

<p>Increases weight gain in breastfed infants (D)</p> Signup and view all the answers

Which hormone found in human milk may contribute to infant satiety?

<p>Leptin (D)</p> Signup and view all the answers

What is the potential metabolic effect after a high-protein meal?

<p>30% (B)</p> Signup and view all the answers

Which physical activities are considered moderate ones according to the text?

<p>Brisk walking and dancing (D)</p> Signup and view all the answers

How many minutes of moderate-intensity exercise are recommended per day?

<p>30 minutes (C)</p> Signup and view all the answers

What is a common misconception about physical activity energy expenditure according to the text?

<p>Most adults overestimate the kilocalories expended in various activities. (C)</p> Signup and view all the answers

What has contributed to an increase in energy intake over the past 30 years?

<p>Calories from sugar-sweetened beverages (B)</p> Signup and view all the answers

What contributes to the distorted perception of physical activity energy expenditure?

<p>Overestimation of actual activity performed (A)</p> Signup and view all the answers

What do OB genes influence according to the text?

<p>BMI and eating behaviors (B)</p> Signup and view all the answers

Where are putative loci related to OB located?

<p>On all chromosomes except X (C)</p> Signup and view all the answers

What is a characteristic of adiposity according to the text?

<p>Varies quantitatively and is heritable (D)</p> Signup and view all the answers

What plays a stronger role in determining offspring obesity according to the text?

<p>Maternal obesity (A)</p> Signup and view all the answers

What is related to the sharp global increase in obesity according to the text?

<p>Gene-environment effect from abundant food supply (B)</p> Signup and view all the answers

What is the association between maternal smoking during pregnancy and obesity (OB) in children and young adults?

<p>50% increased odds of OB (A)</p> Signup and view all the answers

Why do cigarette smokers tend to have lower BMIs compared to nonsmokers?

<p>Nicotine acts as an appetite suppressant (A)</p> Signup and view all the answers

Which class of medications is associated with weight loss?

<p>Dipeptidyl peptidase 4 inhibitors (B)</p> Signup and view all the answers

What is a common observation regarding weight gain after smoking cessation?

<p>Typically 10 pounds or less in the early months (B)</p> Signup and view all the answers

Which factor is NOT associated with predicting weight gain after smoking cessation?

<p>Being of Asian descent (A)</p> Signup and view all the answers

Which medication has been associated with the highest weight gain?

<p>Mirtazapine (D)</p> Signup and view all the answers

How does nicotine affect metabolic rate in individuals who smoke?

<p>Increases metabolic rate by about 200 kcal/25 cigarettes (B)</p> Signup and view all the answers

Which medication is hypothesized to increase carbohydrate craving?

<p>Amitriptyline (C)</p> Signup and view all the answers

Which medication is associated with 1.0- to 4.4-kg weight loss?

<p>Bupropion (C)</p> Signup and view all the answers

Which component is not worsened by weight gain after smoking cessation?

<p>High-density lipoprotein cholesterol (HDL-C) (D)</p> Signup and view all the answers

Which class of medications is weight neutral?

<p>Dipeptidyl peptidase 4 inhibitors (B)</p> Signup and view all the answers

Which statement about diabetes risk and smoking cessation is true?

<p>[Risk for diabetes increases in early years after smoking cessation] (D)</p> Signup and view all the answers

Which medication may result in an initial weight loss followed by weight gain?

<p>Paroxetine (D)</p> Signup and view all the answers

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