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Immunopathology: Antibody Mediated Hypersensitivity Quiz
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Immunopathology: Antibody Mediated Hypersensitivity Quiz

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Questions and Answers

What is the classic clinical demonstration of the function of delayed-type hypersensitivity (DTH) response?

  • Intradermal injection of protein purified derivative (PPD) of mycobacterium (correct)
  • Autoantibodies depositing in heart, joints, skin, kidneys, lungs, and other organs
  • Complement and neutrophil-mediated tissue damage
  • Deposition of immune complexes in capillaries
  • In type III hypersensitivity, if immune complexes are not eliminated, where do they mostly deposit and trigger inflammation?

  • In the capillaries and joints (correct)
  • In the heart and blood vessels
  • In the lungs and kidneys
  • In the liver and nervous system
  • Which disease is commonly associated with the deposition of immune complexes with anti-nuclear autoantibodies in multiple organs such as heart, joints, skin, kidneys, and lungs?

  • Rheumatoid arthritis
  • Multiple sclerosis
  • Psoriasis
  • Systemic lupus erythematosus (correct)
  • Which type of hypersensitivity involves complement and neutrophils as mechanisms of tissue damage?

    <p>Type III hypersensitivity</p> Signup and view all the answers

    What is the mechanism of tissue injury in type IV hypersensitivity?

    <p>T-cell mediated inflammation</p> Signup and view all the answers

    Which mechanism of tissue damage is common to both type III hypersensitivity and type IV hypersensitivity?

    <p>Complement and neutrophils</p> Signup and view all the answers

    In which disease do immune complexes with anti-nuclear autoantibodies most commonly deposit in multiple organs such as heart, joints, skin, kidneys, and lungs?

    <p>Systemic lupus erythematosus</p> Signup and view all the answers

    What is the classic clinical demonstration of the function of delayed-type hypersensitivity (DTH) response?

    <p>Tuberculin skin test</p> Signup and view all the answers

    Where do immune complexes mostly deposit and trigger inflammation if not eliminated in type III hypersensitivity?

    <p>Joints</p> Signup and view all the answers

    Which immune response is initiated when an antigen like purified protein derivative (PPD) of mycobacterium is injected intradermally in an individual?

    <p>Delayed-type hypersensitivity (DTH) response</p> Signup and view all the answers

    What is the classic clinical demonstration of the function of delayed-type hypersensitivity (DTH) response?

    <p>Intradermal injection of protein purified derivative (PPD) of mycobacterium</p> Signup and view all the answers

    Where do immune complexes mostly deposit and trigger inflammation if not eliminated in type III hypersensitivity?

    <p>Capillaries or joints</p> Signup and view all the answers

    Which immune response is initiated when an antigen like protein purified derivative (PPD) of mycobacterium is injected intradermally in an individual?

    <p>Delayed-type hypersensitivity (DTH) response</p> Signup and view all the answers

    In which disease do immune complexes with anti-nuclear autoantibodies most commonly deposit in multiple organs such as heart, joints, skin, kidneys, and lungs?

    <p>Systemic lupus erythematosus</p> Signup and view all the answers

    What is the mechanism of tissue injury in type IV hypersensitivity?

    <p>Cell-mediated immune response</p> Signup and view all the answers

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