Immunology & Serology Part 1 Online Assessment Examination
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Questions and Answers

What determines the ALLOTYPE of an antibody?

  • Constant region of light chain
  • Variable regions of heavy and light chains (correct)
  • Constant regions of heavy and light chains
  • Constant region of heavy chain

Which treatment of IgG results in 3 fragments from each immunoglobulin molecule?

  • 3 (correct)
  • 4
  • 2
  • 5

What dictates the IDIOTYPE of an antibody?

  • Constant region of light chain
  • Variable regions of heavy and light chains (correct)
  • Constant region of heavy chain
  • Constant regions of heavy and light chains

Which immunoglobulin is present in the highest concentration in normal human serum?

<p>IgG (D)</p> Signup and view all the answers

Which of the following is NOT a function of T cells?

<p>Synthesis of antibody (B)</p> Signup and view all the answers

Which T cell expresses the CD8 marker and acts specifically to kill tumors or virally infected cells?

<p>Cytotoxic T (D)</p> Signup and view all the answers

How are cytotoxic T cells (TC cells) and natural killer (NK) cells similar?

<p>Effective against virally infected cells (D)</p> Signup and view all the answers

Which term describes the unique part of the antigen recognized by a corresponding antibody?

<p>Epitope (A)</p> Signup and view all the answers

Which of the following is NOT a Type IV hypersensitivity reaction?

<p>Serum sickness (D)</p> Signup and view all the answers

Anti-CCP (cyclic citrullinated proteins) is specifically associated with which autoimmune disease?

<p>Rheumatoid arthritis (C)</p> Signup and view all the answers

Anti-mitochondrial antibodies are strongly associated with which disease?

<p>Primary biliary cirrhosis (B)</p> Signup and view all the answers

Which disease might be indicated by antibodies to smooth muscle?

<p>Chronic active hepatitis (D)</p> Signup and view all the answers

What condition is associated with an increase in bacterial infections?

<p>Paroxysmal nocturnal hemoglobinuria (C)</p> Signup and view all the answers

Which antibodies are associated with systemic lupus erythematosus?

<p>Systemic lupus erythematosus (D)</p> Signup and view all the answers

What is the flexible portion of the heavy chain of an immunoglobulin molecule located between?

<p>Hinge region (C)</p> Signup and view all the answers

What increases up to 1000x in inflammation?

<p>CRP and serum amyloid A (B)</p> Signup and view all the answers

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