16 Questions
What determines the ALLOTYPE of an antibody?
Variable regions of heavy and light chains
Which treatment of IgG results in 3 fragments from each immunoglobulin molecule?
3
What dictates the IDIOTYPE of an antibody?
Variable regions of heavy and light chains
Which immunoglobulin is present in the highest concentration in normal human serum?
IgG
Which of the following is NOT a function of T cells?
Synthesis of antibody
Which T cell expresses the CD8 marker and acts specifically to kill tumors or virally infected cells?
Cytotoxic T
How are cytotoxic T cells (TC cells) and natural killer (NK) cells similar?
Effective against virally infected cells
Which term describes the unique part of the antigen recognized by a corresponding antibody?
Epitope
Which of the following is NOT a Type IV hypersensitivity reaction?
Serum sickness
Anti-CCP (cyclic citrullinated proteins) is specifically associated with which autoimmune disease?
Rheumatoid arthritis
Anti-mitochondrial antibodies are strongly associated with which disease?
Primary biliary cirrhosis
Which disease might be indicated by antibodies to smooth muscle?
Chronic active hepatitis
What condition is associated with an increase in bacterial infections?
Paroxysmal nocturnal hemoglobinuria
Which antibodies are associated with systemic lupus erythematosus?
Systemic lupus erythematosus
What is the flexible portion of the heavy chain of an immunoglobulin molecule located between?
Hinge region
What increases up to 1000x in inflammation?
CRP and serum amyloid A
This online assessment examination covers topics related to immunology and serology, specifically focusing on Type IV hypersensitivity reactions. Test your knowledge on concepts such as contact sensitivity, elimination of tumor cells, rejection of foreign tissue grafts, and serum sickness.
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