Immunology & Serology Part 1 Online Assessment Examination
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Questions and Answers

What determines the ALLOTYPE of an antibody?

  • Constant region of light chain
  • Variable regions of heavy and light chains (correct)
  • Constant regions of heavy and light chains
  • Constant region of heavy chain

    • Which treatment of IgG results in 3 fragments from each immunoglobulin molecule?

  • 3 (correct)
  • 4
  • 2
  • 5

    • What dictates the IDIOTYPE of an antibody?

  • Constant region of light chain
  • Variable regions of heavy and light chains (correct)
  • Constant region of heavy chain
  • Constant regions of heavy and light chains

    • Which immunoglobulin is present in the highest concentration in normal human serum?

    <p>IgG</p> Signup and view all the answers

    Which of the following is NOT a function of T cells?

    <p>Synthesis of antibody</p> Signup and view all the answers

    Which T cell expresses the CD8 marker and acts specifically to kill tumors or virally infected cells?

    <p>Cytotoxic T</p> Signup and view all the answers

    How are cytotoxic T cells (TC cells) and natural killer (NK) cells similar?

    <p>Effective against virally infected cells</p> Signup and view all the answers

    Which term describes the unique part of the antigen recognized by a corresponding antibody?

    <p>Epitope</p> Signup and view all the answers

    Which of the following is NOT a Type IV hypersensitivity reaction?

    <p>Serum sickness</p> Signup and view all the answers

    Anti-CCP (cyclic citrullinated proteins) is specifically associated with which autoimmune disease?

    <p>Rheumatoid arthritis</p> Signup and view all the answers

    Anti-mitochondrial antibodies are strongly associated with which disease?

    <p>Primary biliary cirrhosis</p> Signup and view all the answers

    Which disease might be indicated by antibodies to smooth muscle?

    <p>Chronic active hepatitis</p> Signup and view all the answers

    What condition is associated with an increase in bacterial infections?

    <p>Paroxysmal nocturnal hemoglobinuria</p> Signup and view all the answers

    Which antibodies are associated with systemic lupus erythematosus?

    <p>Systemic lupus erythematosus</p> Signup and view all the answers

    What is the flexible portion of the heavy chain of an immunoglobulin molecule located between?

    <p>Hinge region</p> Signup and view all the answers

    What increases up to 1000x in inflammation?

    <p>CRP and serum amyloid A</p> Signup and view all the answers

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