Immunology: Innate and Adaptive Immunity
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Questions and Answers

What is the primary function of helper T cells in the immune response?

  • To break down foreign proteins into fragments
  • To engulf and destroy foreign pathogens
  • To directly kill infected cells
  • To recognize and bind to foreign antigens on MHC proteins (correct)
  • Which type of immunity involves the rapid recognition and destruction of foreign antigens?

  • Adaptive immunity
  • Specific immunity
  • Cell-mediated immunity
  • Innate immunity (correct)
  • What characterizes the adaptive immune system?

  • It can only produce antibodies but not cell-mediated responses.
  • It provides immediate defense against all pathogens regardless of type.
  • It includes T lymphocytes and B lymphocytes that respond to specific antigens. (correct)
  • It relies solely on physical barriers like skin.
  • How do B lymphocytes respond when they encounter a foreign antigen?

    <p>They engulf the antigen, process it, and present fragments on MHC proteins. (C)</p> Signup and view all the answers

    What might be the consequence of having an abnormally low number of helper T cells?

    <p>Decreased activation of cytotoxic T cells (C)</p> Signup and view all the answers

    What role do MHC proteins play in the immune response?

    <p>They display protein fragments for recognition by T cells. (D)</p> Signup and view all the answers

    What type of cells are primarily responsible for inducing apoptosis in infected cells?

    <p>Cytotoxic T cells (C)</p> Signup and view all the answers

    Which of the following statements about antigen presentation is true?

    <p>MHC proteins display fragments of proteins present in the cell. (D)</p> Signup and view all the answers

    Flashcards

    Innate Immunity

    The immune response that is rapid and nonspecific, targeting foreign antigens immediately.

    Adaptive Immunity

    A specialized immune response that recognizes specific antigens and mounts tailored responses.

    Cell-mediated Immunity

    A type of adaptive immunity where T lymphocytes target and respond to foreign antigens.

    Humoral Immunity

    A component of adaptive immunity involving B lymphocytes that produce antibodies against antigens.

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    MHC Proteins

    Major histocompatibility complex proteins that display protein fragments (antigens) on cell surfaces.

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    Helper T Cells

    T cells that recognize antigens and activate B lymphocytes and cytotoxic T cells through cytokine release.

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    B Lymphocytes

    Immune cells that bind to foreign antigens and produce antibodies after activation by helper T cells.

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    Cytotoxic T Cells

    Immune cells that destroy infected cells by inducing apoptosis after activation by helper T cells.

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    Study Notes

    Innate and Adaptive Immunity

    • Innate immunity is rapid and non-specific, destroying foreign antigens.
    • Adaptive immunity is specific, divided into cell-mediated and humoral immunity, targeting particular antigens.

    Cell-Mediated Immunity

    • T lymphocytes recognize antigens displayed by MHC proteins on other cells.
    • MHC proteins display fragments of proteins inside a cell.
    • Cells infected with pathogens display foreign antigens on MHC proteins.
    • Helper T cells recognize antigens presented by MHC proteins.
    • They release cytokines, triggering B lymphocyte division.

    Helper T Cell Role

    • Helper T cells bind antigens displayed by B lymphocytes.
    • B lymphocytes engulf foreign antigens, breaking them down.
    • Fragments are presented on MHC proteins.
    • Helper T cells trigger B lymphocyte division and antibody production.
    • They also bind antigens on macrophages and dendritic cells.
    • This stimulates other immune responses, like macrophage phagocytosis and cytotoxic T cell activation.

    Implications of Low Helper T Cell Count

    • A low count of helper T cells affects cytotoxic T cell and B lymphocyte activation.
    • B lymphocytes produce antibodies to target invading pathogens.
    • MHC protein expression is independent of helper T cell count, allowing antigen presentation.

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    Description

    Explore the intricacies of innate and adaptive immunity in this quiz. Learn about the roles of T lymphocytes, helper T cells, and B lymphocytes in the immune response. Test your understanding of how these immune components work together to identify and destroy pathogens.

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