Immunity: Innate and Adaptive Defense Mechanisms Quiz

Study Notes

Immune System Overview

The second line of defense involves natural killer (NK) cells, a type of white blood cell crucial in the innate immune response.
Natural killer (NK) cells primarily function to identify and destroy infected or cancerous cells by inducing apoptosis (programmed cell death).

Target Identification by NK Cells

Natural killer cells recognize their targets through the detection of abnormal markers on the surface of infected or malignant cells, distinguishing them from healthy cells.

Microbial Defense Proteins

Antimicrobial proteins work by attacking microorganisms directly or inhibiting their reproduction, thereby enhancing the body’s innate defense mechanisms.

Role of Interferon

Interferon plays a vital role in the immune response by signaling neighboring cells to enhance their antiviral defenses and activating immune cells, particularly NK cells and macrophages.

Complement System Proteins

The complement system consists of a group of proteins that, when activated, help destroy pathogens and amplify the inflammatory response, enhancing the ability of antibodies to clear infections.

Function of Adaptive Immunity

The primary function of adaptive immunity is to provide a specific defense against pathogens, allowing for a targeted immune response and the development of immunological memory for future encounters.

Protection Against Pathogens

The immune system primarily protects against infectious agents, including viruses, bacteria, and parasites, as well as potential tumors.

B Cell Involvement

Humoral immunity, a component of adaptive immunity, involves B cells which are responsible for producing antibodies that target specific antigens.

Purpose of Leukocytosis

Leukocytosis is an increase in white blood cell count, serving as a protective mechanism to enhance the body's defense against infections and facilitate tissue repair.

Protective Chemicals

An example of a protective chemical in skin and mucous membranes that is NOT included is antibodies, which are primarily associated with adaptive immunity rather than immediate physical barriers.

Function of NK Cells in Innate Immunity

In innate immunity, the primary function of NK cells is to detect and eliminate cells that display signs of stress or infection without prior sensitization.

Inflammatory Response

Inflammation is a physiological response to tissue injury characterized by redness, swelling, heat, and pain, initiated to protect and heal affected areas.

T Cell Involvement

Cell-mediated immunity, a part of adaptive immunity, involves T cells, which are responsible for directly attacking infected or cancerous cells and coordinating the immune response.

Description

Test your knowledge of the body's defense mechanisms against external and internal insults, including lymphocytes, cytokines, MHCs, humoral vs cell-mediated immunity, and innate and adaptive immunity. Explore the two intrinsic defense systems and their cooperative role in protecting the body from diseases.