Podcast
Questions and Answers
What triggers massive brain inflammation in multiple sclerosis?
What triggers massive brain inflammation in multiple sclerosis?
- Autoantibodies
- Microglia
- Autoreactive CD4+ Th1 and Th17 cells (correct)
- Autoreactive CD8+ T cells
What is the primary function of autoreactive CD8+ T cells in autoimmune diseases?
What is the primary function of autoreactive CD8+ T cells in autoimmune diseases?
- Presenting antigens to T cells
- Producing autoantibodies
- Supporting inflammation
- Directly killing self-antigen-expressing cells (correct)
What is the main consequence of autoreactive T cells crossing the blood-brain barrier in multiple sclerosis?
What is the main consequence of autoreactive T cells crossing the blood-brain barrier in multiple sclerosis?
- Demyelination of neurons (correct)
- Rejection of transplanted tissues
- Production of autoantibodies
- Inflammation of the pancreas
What is the primary function of microglia in the central nervous system?
What is the primary function of microglia in the central nervous system?
What is the primary difference between autograft and allograft?
What is the primary difference between autograft and allograft?
What serves as alloantigens in graft rejection?
What serves as alloantigens in graft rejection?
What is the typical outcome of transplanting tissues between non-identical individuals?
What is the typical outcome of transplanting tissues between non-identical individuals?
What is the primary function of hematopoietic stem cells in transplantation?
What is the primary function of hematopoietic stem cells in transplantation?
What is the primary mechanism of autoantibody support in inflammation?
What is the primary mechanism of autoantibody support in inflammation?
What is the primary role of T cells in allograft rejection?
What is the primary role of T cells in allograft rejection?
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