Immunology 101: Blood Composition and Leukocytes Formation

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40 Questions

Which type of leukocytes are granulocytes?

Neutrophils

What is the composition of the middle layer in centrifuged blood, known as the buffy coat?

Leukocytes and platelets

What is the percentage of the sample that the buffy coat occupies in centrifuged blood?

Less than 1%

Which leukocytes are categorized as non-phagocytes?

Lymphocytes

What is the difference between innate and acquired immunity?

Innate immunity is present at birth while acquired immunity develops over time

Which leukocytes are classified as phagocytes?

Monocytes

What do activated B-cells transform into?

Plasma cells

What is the shape of an antibody?

Y-shaped

Which leukocyte is characterized by having multi-lobed nuclei?

Neutrophils

Which type of leukocytes are involved in allergic reactions and parasitic infections?

Eosinophils

What is the process of leukocyte formation called?

Leukopoiesis

Which type of immunity involves the use of antibodies?

Acquired immunity

Which type of white blood cells are mainly responsible for fighting bacterial infections?

Neutrophils

Which type of white blood cells are primarily involved in combating parasitic infections?

Eosinophils

Where do most lymphocytes develop?

Peripheral lymphoid organs

What is the primary function of eosinophils?

Inflammation reduction

Which type of white blood cells is responsible for releasing primarily histamine and other chemicals like bradykinin and serotonin?

Basophils

Which type of immunity is characterized by specific defenses and the production of circulating antibodies?

Humoral immunity

Where are B lymphocytes primarily produced?

Bone marrow

"Plasmablasts" are activated B lymphocytes that eventually develop into:

"Plasma cells"

"IgG" antibodies account for approximately what percentage of total antibodies and have the ability to cross the placenta?

~75%, able to cross placenta

What is the primary function of MHC-I molecules?

Present foreign peptides to cytotoxic T cells

What is the main function of cytotoxic T cells?

Kill infected or abnormal cells

Which type of white blood cells are mainly responsible for presenting foreign peptides to helper T cells?

Macrophages

Which type of leukocytes are primarily responsible for releasing histamine, bradykinin, serotonin, and other substances involved in allergic reactions?

Basophils

What is the primary function of neutrophils among leukocytes?

Phagocytic activity

Which type of leukocytes are mainly responsible for combating parasitic infections and have weak phagocytic activity?

Eosinophils

Where do most B lymphocytes originate from?

Bone marrow

Which component of the antibody structure is responsible for the specificity of the antibody?

Variable portion

Which type of immunoglobulin is involved in opsonization and crosses the placenta?

IgG

"Plasmablasts" are activated B lymphocytes that eventually develop into:

Plasma cells

Which type of leukocytes are categorized as non-phagocytes?

Basophils

Where do most lymphocytes develop?

Thymus

What is the primary function of MHC-I molecules?

Presenting foreign peptides to helper T cells

Which type of immunity involves specific defense mechanisms including humoral immunity and cellular immunity?

Acquired Immunity

Which cytokine primarily stimulates the differentiation of neutrophils and monocytes?

Colony-stimulating factors (CSF)

What is the primary function of basophils?

Releasing histamine and other chemicals

Where do granulocytes and monocytes primarily develop?

Bone marrow

Which leukocytes are classified as non-phagocytes?

Lymphocytes

What is the shape of an erythrocyte (red blood cell)?

Biconcave disc

Test your knowledge on the composition of blood, including the classification of leukocytes as granulocytes vs non-granulocytes, polymorphonuclear vs mononuclear, and phagocytes vs non-phagocytes. This quiz covers the instructional objectives of MCRO 1.1 and MCRO 1.2 in the course.

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