Podcast
Questions and Answers
What is the process by which T cells that bind to self MHC receive signals to trigger apoptosis and die before maturation?
What is the process by which T cells that bind to self MHC receive signals to trigger apoptosis and die before maturation?
- Deletion (apoptosis) (correct)
- Differentiation
- Activation
- Proliferation
Which type of T cells can develop into Regulatory T cells?
Which type of T cells can develop into Regulatory T cells?
- B cells
- Natural Killer cells
- CD8 T cells
- CD4 T cells (correct)
What happens to immature B lymphocytes that react with self antigens in the bone marrow?
What happens to immature B lymphocytes that react with self antigens in the bone marrow?
- They undergo proliferation
- They differentiate into plasma cells
- They undergo positive selection
- They are killed (negative selection) (correct)
What occurs when immature B lymphocytes undergo receptor editing?
What occurs when immature B lymphocytes undergo receptor editing?
Where does central tolerance occur for self antigens?
Where does central tolerance occur for self antigens?
What happens to immature lymphocytes that react with self antigens?
What happens to immature lymphocytes that react with self antigens?
Which process involves T cells becoming functionally inactivated when recognizing antigens without adequate costimulators?
Which process involves T cells becoming functionally inactivated when recognizing antigens without adequate costimulators?
How do self-reactive T cells ignore self antigens in the process of clonal ignorance?
How do self-reactive T cells ignore self antigens in the process of clonal ignorance?
What occurs when T regulatory cells recognize self antigens in the thymus or peripheral tissue?
What occurs when T regulatory cells recognize self antigens in the thymus or peripheral tissue?
What happens to mature B lymphocytes that are activated to self antigen without T cell assistance?
What happens to mature B lymphocytes that are activated to self antigen without T cell assistance?
Why do mature B lymphocytes that are activated to self antigen become incapable of responding to that antigen?
Why do mature B lymphocytes that are activated to self antigen become incapable of responding to that antigen?
