Podcast
Questions and Answers
What is the main function of the VH region in an immunoglobulin structure?
What is the main function of the VH region in an immunoglobulin structure?
- Fc receptor binding
- Mast cell degranulation
- Complement activation
- Antigen binding (correct)
Which process involves the release of histamine from mast cells triggered by antibodies?
Which process involves the release of histamine from mast cells triggered by antibodies?
- Opsonization
- Mast cell degranulation (correct)
- ADCC
- Neutralization
Which Ig region is primarily responsible for activating B lymphocytes?
Which Ig region is primarily responsible for activating B lymphocytes?
- Fab domain (correct)
- VL region
- CH region
- CL region
Which biological function of antibodies involves enhancing phagocytosis of pathogens by macrophages?
Which biological function of antibodies involves enhancing phagocytosis of pathogens by macrophages?
Which process involves antibody-dependent cell-mediated cytotoxicity (ADCC)?
Which process involves antibody-dependent cell-mediated cytotoxicity (ADCC)?
What is responsible for antibody diversity?
What is responsible for antibody diversity?
What stabilizes the structure of the constant region of light chains?
What stabilizes the structure of the constant region of light chains?
Which component determines the class (isotype) of an antibody?
Which component determines the class (isotype) of an antibody?
Where are secreted forms of antibodies found?
Where are secreted forms of antibodies found?
What stabilizes the structure of IgA antibodies?
What stabilizes the structure of IgA antibodies?
What is present in plasma when blood clots?
What is present in plasma when blood clots?
Which antibody class is most abundant in serum and has four different subclasses with varying biological activity?
Which antibody class is most abundant in serum and has four different subclasses with varying biological activity?
Which antibody plays a significant role in neonatal immunity by crossing the placenta to enter the fetal circulation?
Which antibody plays a significant role in neonatal immunity by crossing the placenta to enter the fetal circulation?
Which antibody class is predominantly secreted in external secretions like saliva, tears, breast milk, and mucus?
Which antibody class is predominantly secreted in external secretions like saliva, tears, breast milk, and mucus?
Which antibody class serves as an antigen receptor on naïve B cells when in its monomeric form?
Which antibody class serves as an antigen receptor on naïve B cells when in its monomeric form?
Which antibody class can be found minimally in interstitial fluid due to its large size but can still be present in secretions?
Which antibody class can be found minimally in interstitial fluid due to its large size but can still be present in secretions?
Which antibody class binds to a poly-Ig receptor on the basolateral membrane of an epithelial cell for internalization in secretory IgA formation?
Which antibody class binds to a poly-Ig receptor on the basolateral membrane of an epithelial cell for internalization in secretory IgA formation?
What is the function of Fc receptors on immune cells?
What is the function of Fc receptors on immune cells?
Which immunoglobulins can activate the classical pathway of complement?
Which immunoglobulins can activate the classical pathway of complement?
What is the role of BCR Complex formed by Ig-α/Ig-β?
What is the role of BCR Complex formed by Ig-α/Ig-β?
Which antibody effector function involves prohibiting attachment of microbes to host surfaces?
Which antibody effector function involves prohibiting attachment of microbes to host surfaces?
What must be true for IgG and IgM antibodies to activate complement?
What must be true for IgG and IgM antibodies to activate complement?
Which immune cells recognize antibodies through Fc receptors?
Which immune cells recognize antibodies through Fc receptors?
Which type of immune response involves enhanced phagocytosis by macrophages and neutrophils?
Which type of immune response involves enhanced phagocytosis by macrophages and neutrophils?
What is the mechanism of action in Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)?
What is the mechanism of action in Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)?
Which cell type is NOT involved in Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)?
Which cell type is NOT involved in Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)?
In Mast Cell and Basophil degranulation, the process is initiated by binding of which molecule?
In Mast Cell and Basophil degranulation, the process is initiated by binding of which molecule?
What is the primary function of Fc receptors in the immune response?
What is the primary function of Fc receptors in the immune response?
Which process is associated with opsonization in the immune response?
Which process is associated with opsonization in the immune response?
