Immunoglobulin G Overview
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Questions and Answers

Which immunoglobulin is usually a monomer, much less abundant in the circulation, and exists bound at its Fc region to receptors on mast cells and basophils?

  • IgE (correct)
  • IgA
  • IgM
  • IgD
  • What happens when IgE encounters the antigen that elicited its production?

  • It enhances phagocytosis by macrophages
  • It triggers the release of cytokines
  • It activates T cells directly
  • It triggers the liberation of histamine and leukotrienes (correct)
  • Which immunoglobulin is the least abundant in plasma and is also the least understood class of antibody?

  • IgM
  • IgE
  • IgD (correct)
  • IgA
  • Where are monomers of IgD typically bound in the body?

    <p>To B lymphocytes</p> Signup and view all the answers

    Which immunoglobulin, along with IgM, acts as an antigen receptor in triggering B-cell activation?

    <p>IgD</p> Signup and view all the answers

    Which immunoglobulin class is the most abundant in blood, representing 75%-85% of the total immunoglobulins?

    <p>IgG</p> Signup and view all the answers

    In which immunoglobulin class are the heavy chains of two monomers united by a polypeptide called the J chain?

    <p>IgA</p> Signup and view all the answers

    Which immunoglobulin class is mainly produced in the initial response to an antigen?

    <p>IgM</p> Signup and view all the answers

    Which immunoglobulin class is highly soluble, stable, and can provide passive immunity against certain infections to the newborn through the placental barrier?

    <p>IgA</p> Signup and view all the answers

    Which immunoglobulin class is released by plasma cells in mucosae of the digestive, respiratory, and reproductive tracts?

    <p>IgE</p> Signup and view all the answers

    Which immunoglobulin class is most effective in activating the complement system when bound to an antigen?

    <p>IgM</p> Signup and view all the answers

    Which antibody is a pentamer structure with a J chain and secretory component?

    <p>IgA</p> Signup and view all the answers

    Which antibody activates phagocytosis and neutralizes antigens?

    <p>IgG</p> Signup and view all the answers

    Which antibody is the first antibody produced in the initial immune response and activates complement?

    <p>IgM</p> Signup and view all the answers

    Where is IgE primarily found in the body?

    <p>Bound to the surface of mast cells and basophils</p> Signup and view all the answers

    Which antibodies are able to bind specifically and neutralize certain viral particles and bacterial toxins?

    <p>IgG and IgA</p> Signup and view all the answers

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