Podcast
Questions and Answers
Which immunoglobulin is usually a monomer, much less abundant in the circulation, and exists bound at its Fc region to receptors on mast cells and basophils?
Which immunoglobulin is usually a monomer, much less abundant in the circulation, and exists bound at its Fc region to receptors on mast cells and basophils?
- IgE (correct)
- IgA
- IgM
- IgD
What happens when IgE encounters the antigen that elicited its production?
What happens when IgE encounters the antigen that elicited its production?
- It enhances phagocytosis by macrophages
- It triggers the release of cytokines
- It activates T cells directly
- It triggers the liberation of histamine and leukotrienes (correct)
Which immunoglobulin is the least abundant in plasma and is also the least understood class of antibody?
Which immunoglobulin is the least abundant in plasma and is also the least understood class of antibody?
- IgM
- IgE
- IgD (correct)
- IgA
Where are monomers of IgD typically bound in the body?
Where are monomers of IgD typically bound in the body?
Which immunoglobulin, along with IgM, acts as an antigen receptor in triggering B-cell activation?
Which immunoglobulin, along with IgM, acts as an antigen receptor in triggering B-cell activation?
Which immunoglobulin class is the most abundant in blood, representing 75%-85% of the total immunoglobulins?
Which immunoglobulin class is the most abundant in blood, representing 75%-85% of the total immunoglobulins?
In which immunoglobulin class are the heavy chains of two monomers united by a polypeptide called the J chain?
In which immunoglobulin class are the heavy chains of two monomers united by a polypeptide called the J chain?
Which immunoglobulin class is mainly produced in the initial response to an antigen?
Which immunoglobulin class is mainly produced in the initial response to an antigen?
Which immunoglobulin class is highly soluble, stable, and can provide passive immunity against certain infections to the newborn through the placental barrier?
Which immunoglobulin class is highly soluble, stable, and can provide passive immunity against certain infections to the newborn through the placental barrier?
Which immunoglobulin class is released by plasma cells in mucosae of the digestive, respiratory, and reproductive tracts?
Which immunoglobulin class is released by plasma cells in mucosae of the digestive, respiratory, and reproductive tracts?
Which immunoglobulin class is most effective in activating the complement system when bound to an antigen?
Which immunoglobulin class is most effective in activating the complement system when bound to an antigen?
Which antibody is a pentamer structure with a J chain and secretory component?
Which antibody is a pentamer structure with a J chain and secretory component?
Which antibody activates phagocytosis and neutralizes antigens?
Which antibody activates phagocytosis and neutralizes antigens?
Which antibody is the first antibody produced in the initial immune response and activates complement?
Which antibody is the first antibody produced in the initial immune response and activates complement?
Where is IgE primarily found in the body?
Where is IgE primarily found in the body?
Which antibodies are able to bind specifically and neutralize certain viral particles and bacterial toxins?
Which antibodies are able to bind specifically and neutralize certain viral particles and bacterial toxins?
