16 Questions
Which immunoglobulin is usually a monomer, much less abundant in the circulation, and exists bound at its Fc region to receptors on mast cells and basophils?
IgE
What happens when IgE encounters the antigen that elicited its production?
It triggers the liberation of histamine and leukotrienes
Which immunoglobulin is the least abundant in plasma and is also the least understood class of antibody?
IgD
Where are monomers of IgD typically bound in the body?
To B lymphocytes
Which immunoglobulin, along with IgM, acts as an antigen receptor in triggering B-cell activation?
IgD
Which immunoglobulin class is the most abundant in blood, representing 75%-85% of the total immunoglobulins?
IgG
In which immunoglobulin class are the heavy chains of two monomers united by a polypeptide called the J chain?
IgA
Which immunoglobulin class is mainly produced in the initial response to an antigen?
IgM
Which immunoglobulin class is highly soluble, stable, and can provide passive immunity against certain infections to the newborn through the placental barrier?
IgA
Which immunoglobulin class is released by plasma cells in mucosae of the digestive, respiratory, and reproductive tracts?
IgE
Which immunoglobulin class is most effective in activating the complement system when bound to an antigen?
IgM
Which antibody is a pentamer structure with a J chain and secretory component?
IgA
Which antibody activates phagocytosis and neutralizes antigens?
IgG
Which antibody is the first antibody produced in the initial immune response and activates complement?
IgM
Where is IgE primarily found in the body?
Bound to the surface of mast cells and basophils
Which antibodies are able to bind specifically and neutralize certain viral particles and bacterial toxins?
IgG and IgA
This quiz covers the structure, function, and characteristics of Immunoglobulin G (IgG) antibodies. Topics include the formation of disulfide bonds, antigen binding, Fc receptors, abundance in blood, and properties like solubility and stability.
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