Podcast
Questions and Answers
Which of the following is the primary function of the innate immune system?
Which of the following is the primary function of the innate immune system?
- Targeting and destroying specific abnormal host cells
- Providing a rapid, non-specific defense against a broad range of threats (correct)
- Producing antibodies specific to pathogens
- Forming memory cells for long-term immunity
Which of the following cells is NOT considered a phagocyte?
Which of the following cells is NOT considered a phagocyte?
- Neutrophils
- Natural Killer Cells (correct)
- Dendritic Cells
- Macrophages
What role do mast cells primarily play in the immune response?
What role do mast cells primarily play in the immune response?
- Presenting antigens to activate T cells
- Engulfing and destroying pathogens
- Producing antibodies to target pathogens
- Initiating inflammation by releasing histamine (correct)
How do Natural Killer Cells (NKCs) identify cells to destroy?
How do Natural Killer Cells (NKCs) identify cells to destroy?
Which cell type is responsible for bridging the innate and adaptive immune systems?
Which cell type is responsible for bridging the innate and adaptive immune systems?
What is the primary function of cytotoxic T cells?
What is the primary function of cytotoxic T cells?
Which of the following immune cells is responsible for producing antibodies?
Which of the following immune cells is responsible for producing antibodies?
What is the combined role of memory T cells and memory B cells in the adaptive immune response?
What is the combined role of memory T cells and memory B cells in the adaptive immune response?
Flashcards
Immune System
Immune System
The body's defense system against threats like germs, injuries, and foreign substances.
Innate Immunity
Innate Immunity
The first line of defense against pathogens, including skin, mucous membranes, and chemicals like lysozyme and stomach acid.
Adaptive Immunity
Adaptive Immunity
The second line of defense, specifically targeting and remembering pathogens.
Inflammation Response
Inflammation Response
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Leukocytes
Leukocytes
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Natural Killer Cells (NKCs)
Natural Killer Cells (NKCs)
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Dendritic Cells
Dendritic Cells
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Memory T Cells
Memory T Cells
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Study Notes
Immune System
- The immune system is the body's defense mechanism against threats like mechanical injuries, germs, and foreign particles.
- It's composed of cells that patrol the body and fight off threats.
- It's divided into innate and adaptive immunity.
Innate Immunity
- First Line of Defense: Skin and mucous membranes prevent pathogen entry.
- Chemical Barriers: Lysozyme in eyes and stomach acid kill pathogens.
- Normal Flora: Microbial communities compete with pathogens for resources.
Inflammation Response
- Mast cells release histamine, triggering inflammation.
- Histamine attracts leukocytes to the affected area.
Leukocytes
- Phagocytes:
- Neutrophils: Abundant, patrol, respond quickly to breaches, die after killing pathogens, form pus.
- Macrophages: Large, engulf pathogens (up to 100), eliminate rogue cells (like cancer).
- Natural Killer Cells (NKCs): Destroy abnormal cells by detecting lack of MHC proteins.
Dendritic Cells
- Found in external environment interaction areas (nose, lungs).
- Bridge innate and adaptive immunity.
- Capture, process pathogens and present antigen info to T cells.
Adaptive Immunity
- More effective than innate immunity, recognizes specific pathogens.
- Two main components: T lymphocytes (T cells) and B lymphocytes (B cells).
T Cells
- Helper T cells: Activated by dendritic cells or macrophages.
- Form effector T cells: signal other white blood cells to fight.
- Form memory T cells: retain antigen record for future response.
- Cytotoxic T cells: Eliminate infected or dying cells through apoptosis.
B Cells
- Produce antibodies: bind to pathogen antigens, mark for destruction by macrophages.
- Form memory B cells: retain antigen info for improved future responses.
Memory Cells
- Memory T and B cells provide long-term immunity.
Immune System Overview
- Innate immunity is fast and non-specific, providing initial defense.
- Adaptive immunity is slower, specific, targets pathogens, and builds long-term protection.
- Essential for health, infection prevention, and threat response.
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