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Questions and Answers
The complement is a family of more than twenty different proteins in serum that function as a non-specific defense against ______.
The complement is a family of more than twenty different proteins in serum that function as a non-specific defense against ______.
infection
Interferons are small proteins produced by eukaryotic cells in response to ______ infection.
Interferons are small proteins produced by eukaryotic cells in response to ______ infection.
viral
Alveolar macrophages, along with neutrophils and natural killer cells, remove particles and organisms that enter the ______.
Alveolar macrophages, along with neutrophils and natural killer cells, remove particles and organisms that enter the ______.
alveoli
Normal flora refers to the large number of microorganisms in the human body that are generally ______.
Normal flora refers to the large number of microorganisms in the human body that are generally ______.
The inflammatory response is the vascular and cellular reaction to the presence of invading microorganisms or ______.
The inflammatory response is the vascular and cellular reaction to the presence of invading microorganisms or ______.
The process of inflammation may be divided into several stages, including initiation, tissue response, leukocyte response, and ______.
The process of inflammation may be divided into several stages, including initiation, tissue response, leukocyte response, and ______.
Damaged cells at the site of injury release chemical factors such as ______, which trigger vasodilatation.
Damaged cells at the site of injury release chemical factors such as ______, which trigger vasodilatation.
Phagocytic cells accomplish the leukocyte response by ______ the microbes and damaged tissue.
Phagocytic cells accomplish the leukocyte response by ______ the microbes and damaged tissue.
Blood clots around the site prevent the microbe or its products from spreading to the other part of the ______.
Blood clots around the site prevent the microbe or its products from spreading to the other part of the ______.
Some individuals of the same race and same species can have varied experiences with certain ______.
Some individuals of the same race and same species can have varied experiences with certain ______.
Very old people and young ones are more susceptible to infections when compared to ______.
Very old people and young ones are more susceptible to infections when compared to ______.
Any individual under corticosteroid hormone treatment is more susceptible to ______.
Any individual under corticosteroid hormone treatment is more susceptible to ______.
Individuals of different races within the same species have varied susceptibility or resistance toward ______.
Individuals of different races within the same species have varied susceptibility or resistance toward ______.
Sickle cell anaemia causes an alteration of the shape of the ______, which prevents its parasitisation.
Sickle cell anaemia causes an alteration of the shape of the ______, which prevents its parasitisation.
Physical and chemical barriers prevent the entry of foreign ______.
Physical and chemical barriers prevent the entry of foreign ______.
Gastric acidity, whose high pH prevents the entry of pathogens inside the body by ______ effect.
Gastric acidity, whose high pH prevents the entry of pathogens inside the body by ______ effect.
Immunity can be defined as the way in which the body can protect itself from invasion by pathogenic ______.
Immunity can be defined as the way in which the body can protect itself from invasion by pathogenic ______.
The reaction to foreign substances is described as ______.
The reaction to foreign substances is described as ______.
Non-specific immunity is also called ______ immunity.
Non-specific immunity is also called ______ immunity.
The two major groups of immunity are non specific immunity and ______ immunity.
The two major groups of immunity are non specific immunity and ______ immunity.
The unbroken skin and mucus membrane serve as effective mechanical barriers to infectious ______.
The unbroken skin and mucus membrane serve as effective mechanical barriers to infectious ______.
Maternal passive immunity is antibody-mediated immunity that is passed to the fetus through the ______.
Maternal passive immunity is antibody-mediated immunity that is passed to the fetus through the ______.
Keratin is a skin ______ produced by the outermost cells of the skin.
Keratin is a skin ______ produced by the outermost cells of the skin.
The only antibody isotype that can pass through the placenta is ______.
The only antibody isotype that can pass through the placenta is ______.
Hydrochloric acid and bile salt inhibit the growth of microorganisms in the gastrointestinal ______.
Hydrochloric acid and bile salt inhibit the growth of microorganisms in the gastrointestinal ______.
Passive immunity can also be provided through the transfer of IgA antibodies found in ______ milk.
Passive immunity can also be provided through the transfer of IgA antibodies found in ______ milk.
Mucous production and ciliary movement protect the ______ cavity and throat.
Mucous production and ciliary movement protect the ______ cavity and throat.
Colostrum present in mother's milk is an example of ______ immunity.
Colostrum present in mother's milk is an example of ______ immunity.
The action of ______ removes mucus that contains microorganisms from the respiratory tract.
The action of ______ removes mucus that contains microorganisms from the respiratory tract.
The soft, spongy tissue found in bone cavities is known as ______.
The soft, spongy tissue found in bone cavities is known as ______.
Tears wash the conjunctiva and perform a similar defensive function as the urine in the ______.
Tears wash the conjunctiva and perform a similar defensive function as the urine in the ______.
Lysozyme is an enzyme that can break down the cell wall of ______-positive bacteria.
Lysozyme is an enzyme that can break down the cell wall of ______-positive bacteria.
Flashcards
Non-Specific Immunity
Non-Specific Immunity
The body's natural defense against pathogens. It's like a general, non-specific army, acting quickly to fight off any invaders.
Specific Immunity
Specific Immunity
A type of immunity specifically targeting particular pathogens. It's like a trained army, remembering enemies and fighting them effectively.
Maternal Passive Immunity
Maternal Passive Immunity
Antibodies from the mother transferred to the baby during pregnancy. It's like a temporary protection until the baby can build its own immunity.
Breast milk Immunity
Breast milk Immunity
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Immune Self-Recognition
Immune Self-Recognition
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Inflammation
Inflammation
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Immune Tolerance
Immune Tolerance
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Immune Homeostasis
Immune Homeostasis
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Keratin
Keratin
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Lysozyme
Lysozyme
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Physical or mechanical barrier
Physical or mechanical barrier
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Hydrochloric acid
Hydrochloric acid
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Bile salt
Bile salt
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Ciliary movement
Ciliary movement
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Mucus
Mucus
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Complement system
Complement system
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Interferons
Interferons
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Alveolar macrophages
Alveolar macrophages
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Neutrophils
Neutrophils
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Natural killer cells
Natural killer cells
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Normal flora
Normal flora
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Inflammatory response
Inflammatory response
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Tissue Response in Inflammation
Tissue Response in Inflammation
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Individual Immunity
Individual Immunity
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Racial Immunity
Racial Immunity
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Species Immunity
Species Immunity
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What is the primary function of innate immunity?
What is the primary function of innate immunity?
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What happens in innate immunity when infections are established?
What happens in innate immunity when infections are established?
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How does innate immunity contribute to adaptive immunity?
How does innate immunity contribute to adaptive immunity?
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Give an example of innate immunity- gastric acidity
Give an example of innate immunity- gastric acidity
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Study Notes
Immunity Definition
- Immunity is the body's defense mechanisms against pathogens and harmful effects.
- Reaction to foreign substances is inflammation.
- Non-reaction to self substances is immunity.
- Health is a physical state where the self is immunologically spared, and foreign substances are eliminated.
- Disease arises when foreign substances aren't eliminated, or self-substances aren't spared.
Immunity Types
- Immunity is classified into two major groups:
- Innate Immunity: The first line of defense against any infection.
- Adaptive Immunity: Provides a more specific and targeted response.
Innate Components
- Adenoids: Two glands located in the nasal passage
- Bone Marrow: Soft, spongy tissue found in bone cavities
- Lymph Nodes: Small bean-shaped organs throughout the body, connected by lymphatic vessels.
- Lymphatic Vessels: A network of channels carrying lymphocytes to lymphoid organs and bloodstream.
- Peyer Patches: Lymphoid tissue in the small intestine.
- Spleen: A fist-sized organ located in the abdominal cavity.
- Thymus: Two lobes in front of the windpipe, behind the breastbone.
- Tonsils: Two oval masses at the back of the throat.
Non-Specific (Innate) Immunity
- Physical or Mechanical Barriers: Skin and mucus membranes are essential preventative barriers
- Low moisture, low pH, secreted inhibitory substances inhibit microbial growth.
- Biochemical Factors: Chemical secretions inhibiting microbial growth.
- Keratin (skin protein) creates a dry environment.
- Cellular Mechanisms:
- Alveolar macrophages and neutrophils phagocytize microbes.
- Natural killer cells kill undesirable cells (tumors, viruses).
- Normal Flora: Microorganisms in the body, helping prevent pathogenic organisms.
- Inflammatory Reactions: A vascular and cellular response to injury or infection.
- Localized response with increased blood flow, permeability, and cell recruitment.
Types of Innate Immunity
- Individual Immunity: Variations in susceptibility to infections, based on individual experiences and genetic factors (e.g., age, gender).
- Racial Immunity: Differences in susceptibility to particular infections based on race.
- Species Immunity: Differences in susceptibility to specific infections between different species.
Significance of Innate Immunity
- Physical and chemical barriers prevent foreign material entry.
- Complement reactions and phagocytosis clear infections.
- Activates the adaptive immune response.
- Examples include gastric acidity, skin as a barrier.
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