Immune System Cells: Neutrophils and Eosinophils
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Questions and Answers

Where do T cells originate from?

  • Spleen and thymus
  • Lymph nodes and red bone marrow
  • Kidneys and pancreas
  • Fetal liver and adult bone marrow (correct)

What is the main site of maturation for T cells?

  • Lymph nodes
  • Bone marrow
  • Spleen
  • Thymus (correct)

What is the primary marker expressed by double negative (DN) T cells?

  • CD4
  • CD8
  • TCR (correct)
  • CD3

After gene rearrangement of the TCR, what do thymocytes express?

<p>Both CD4 and CD8 (C)</p> Signup and view all the answers

Where are the most immature thymocytes found?

<p>Subcapsular sinus (A)</p> Signup and view all the answers

What is the consequence of thymus involution with age?

<p>Decreased output of mature T cells (A)</p> Signup and view all the answers

Where do neutrophils and eosinophils mostly develop?

<p>Bone marrow (D)</p> Signup and view all the answers

Which cytokines stimulate the maturation of eosinophils from their myeloid precursors?

<p>Granulocyte monocyte colony stimulating factor (G-MCSF) (A)</p> Signup and view all the answers

Where are some eosinophils normally present in the body?

<p>Mucosal linings of respiratory, gastrointestinal, and genitourinary tracts (B)</p> Signup and view all the answers

What is the primary function of basophils in the immune system?

<p>Release of histamine in allergic reactions (C)</p> Signup and view all the answers

From where do monocytes/macrophages originate?

<p>Bone marrow (B)</p> Signup and view all the answers

What is the collective term for monocytes/macrophages in the immune system?

<p>Mononuclear phagocyte system (C)</p> Signup and view all the answers

Which cells are the source of tissue resident macrophages?

<p>Monocytes (D)</p> Signup and view all the answers

What is the cytokine responsible for the maturation of dendritic cells?

<p>Flt3 ligand (D)</p> Signup and view all the answers

Which cells are widely distributed in lymphoid tissues, mucosal epithelium, and organ parenchyma?

<p>Macrophages (A)</p> Signup and view all the answers

What is the important function of mast cells in allergic diseases?

<p>Mediator release like histamine (C)</p> Signup and view all the answers

Which cells have multiple cytoplasmic projections making them efficient antigen presenting cells?

<p>Dendritic cells (D)</p> Signup and view all the answers

What lineage do myeloid cells, including neutrophils and eosinophils, derive from?

<p>Hematopoietic stem cell (A)</p> Signup and view all the answers

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