Neutrophils and the Immune System SAQ

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What are the functions of neutrophils?

Neutrophils play a role in acute bacterial infections and their numbers increase in response to such infections.

What is the lifespan of eosinophils in the bloodstream and connective tissues?

Eosinophils circulate in the bloodstream for 6-8 hours and their lifespan in connective tissues is 8-10 days.

What clinical conditions can cause an increase in basophil count?

Clinical conditions such as hay fever, urticaria (hives), chronic sinusitis, and some leukemias can cause an increase in basophil count.

What is the role of monocytes in the body?

<p>Monocytes are immediate precursors to cells of the monocyte-macrophage system and perform their functions outside the circulation by entering connective tissues to become macrophages or phagocytes.</p> Signup and view all the answers

What are the different stages of development in the erythroid lineage?

<p>proerythroblast (Pr), basophilic erythroblast (BE), early polychromatophilic erythroblast (PE)</p> Signup and view all the answers

What are the two unidentifiable cells seen in the image?

<p>arrows</p> Signup and view all the answers

What is the function of erythrocytes (red blood cells)?

<p>transporting O2 from lungs to tissues and returning CO2 from tissues to lungs for elimination</p> Signup and view all the answers

What is the lifespan of RBCs in circulation?

<p>120 days</p> Signup and view all the answers

Name the cellular components of blood and describe their functions.

<p>The cellular components of blood include red blood cells, white blood cells, and platelets. Red blood cells carry oxygen to the tissues, white blood cells help to fight off infections, and platelets are involved in blood clot formation and tissue repair.</p> Signup and view all the answers

What is the function of blood in the body?

<p>The function of blood is to transport oxygen and nutrients to the lungs and tissues, form blood clots to prevent blood loss, carry immune cells, and deliver waste products to the kidneys and liver for filtration and cleaning.</p> Signup and view all the answers

Where does blood formation (haemopoiesis) occur and at what stages of development?

<p>Blood formation occurs in the bone marrow. During the first few weeks of gestation, it occurs in the yolk sac. Around 6 weeks of development, it shifts to the liver and spleen. Finally, from 6-7 months of fetal life onwards, it primarily occurs in the bone marrow.</p> Signup and view all the answers

What are the functions of B cells and T cells in the immune response?

<p>B cells produce and secrete antibodies, while T cells recognize invaders, activate the immune response, kill infected or abnormal cells, coordinate immune functions, and establish immunological memory.</p> Signup and view all the answers

What is the difference between heterochromatin and euchromatin?

<p>Heterochromatin is tightly packed form of DNA, while euchromatin is loosely packed form of DNA.</p> Signup and view all the answers

What is the function of lymph nodes?

<p>Lymph nodes filter lymph and detect infections from peripheral tissues, returning interstitial fluid to circulation.</p> Signup and view all the answers

Why are high endothelial venules (HEVs) important in the immune response?

<p>HEVs allow for interactions between lymphocytes and endothelial cells, facilitating lymphocyte extravasation.</p> Signup and view all the answers

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