18 Questions
What is the likely initial causative event in autoimmune diseases?
Pathogen invasion with mild symptoms
Why are females more likely to suffer from autoimmune diseases?
They have a more activated immune system than males
What is the affected tissue in Rheumatoid arthritis?
Synovium surrounding joints
What is the origin of corticosteroids in the human body?
Adrenal cortex
What is the type of hypersensitivity reaction associated with autoimmune diseases?
Type II – IV hypersensitivity reactions
What is the function of oligodendrocytes in the central nervous system?
Wrapping myelin around central nervous system axons
What is the mechanism by which the innate immune system recognizes bacteria?
Through binding of PAMPs to Toll-Like Receptors (TLRs)
What is the characteristic of the innate immune response?
Ready for immediate action and non-specific
What is the result of the attack of the immune system on bacteria?
Formation of pus
What is the type of immune response that is specific to particular pathogens?
Adaptive immune response
What are the important targets for drug therapy in the immune response?
Both innate and adaptive immune responses
What is the role of cytokines in the innate immune response?
To signal endothelial cells
What is the role of IKB in cell signaling?
To activate NF-kB
What is the sequence of events for neutrophils to invade infected tissue?
Rolling, Adhesion, Flattening, Transmigration
What is the function of major histocompatibility complex 2 (MHC2)?
To present antigens to T cells
What type of T cells are involved in allergic responses?
Th2 cells
What is the target of drugs used to combat autoimmune diseases?
Interleukin 2
What is the characteristic of autoimmune diseases?
The immune system becomes directed against the body’s own tissues
Test your knowledge on the immune system, including the differences between innate and adaptive immune responses, and how they relate to pain relief. Explore the concepts of nonspecific and specific responses to pathogens and their importance in human health.
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