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Immune System and Pain Response

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Questions and Answers

What is the likely initial causative event in autoimmune diseases?

Inflammatory episodes

Pathogen invasion with mild symptoms (correct)

Immune system attack on endogenous proteins

Immune attack on body's own tissues

Why are females more likely to suffer from autoimmune diseases?

They have a more activated immune system than males (correct)

They have a less activated immune system than males

They have a weaker immune response to infections

They are more prone to pathogen invasion

What is the affected tissue in Rheumatoid arthritis?

Pancreatic beta cells

Thyroid gland

Synovium surrounding joints (correct)

Oligodendrocytes

What is the origin of corticosteroids in the human body?

Adrenal cortex Signup and view all the answers

What is the type of hypersensitivity reaction associated with autoimmune diseases?

Type II – IV hypersensitivity reactions Signup and view all the answers

What is the function of oligodendrocytes in the central nervous system?

Wrapping myelin around central nervous system axons Signup and view all the answers

What is the mechanism by which the innate immune system recognizes bacteria?

Through binding of PAMPs to Toll-Like Receptors (TLRs) Signup and view all the answers

What is the characteristic of the innate immune response?

Ready for immediate action and non-specific Signup and view all the answers

What is the result of the attack of the immune system on bacteria?

Formation of pus Signup and view all the answers

What is the type of immune response that is specific to particular pathogens?

Adaptive immune response Signup and view all the answers

What are the important targets for drug therapy in the immune response?

Both innate and adaptive immune responses Signup and view all the answers

What is the role of cytokines in the innate immune response?

To signal endothelial cells Signup and view all the answers

What is the role of IKB in cell signaling?

To activate NF-kB Signup and view all the answers

What is the sequence of events for neutrophils to invade infected tissue?

Rolling, Adhesion, Flattening, Transmigration Signup and view all the answers

What is the function of major histocompatibility complex 2 (MHC2)?

To present antigens to T cells Signup and view all the answers

What type of T cells are involved in allergic responses?

Th2 cells Signup and view all the answers

What is the target of drugs used to combat autoimmune diseases?

Interleukin 2 Signup and view all the answers

What is the characteristic of autoimmune diseases?

The immune system becomes directed against the body’s own tissues Signup and view all the answers