Podcast
Questions and Answers
What is the primary function of CD8+ cytotoxic T lymphocytes?
What is the primary function of CD8+ cytotoxic T lymphocytes?
- To activate macrophages to destroy phagocytosed microbes
- To stimulate the production of antibodies against extracellular microbes
- To kill infected cells (correct)
- To recognize extracellular microbes through class II MHC pathway
Which MHC pathway is associated with the recognition of protein antigens from microbes that live in the cytoplasm of infected cells?
Which MHC pathway is associated with the recognition of protein antigens from microbes that live in the cytoplasm of infected cells?
- Class III MHC pathway
- Antigen-independent pathway
- Class II MHC pathway
- Class I MHC pathway (correct)
What is the role of CD4+ helper T lymphocytes in the immune response?
What is the role of CD4+ helper T lymphocytes in the immune response?
- To present antigens to B lymphocytes
- To activate macrophages to destroy phagocytosed microbes
- To recognize and eliminate infected cells
- To stimulate the production of antibodies against extracellular microbes (correct)
How do protein antigens from microbes that are endocytosed by macrophages and B lymphocytes enter the MHC pathway?
How do protein antigens from microbes that are endocytosed by macrophages and B lymphocytes enter the MHC pathway?
What is the main difference between the class I and class II MHC pathways?
What is the main difference between the class I and class II MHC pathways?
What is the ultimate goal of MHC-associated antigen presentation by CD8+ and CD4+ effector T cells?
What is the ultimate goal of MHC-associated antigen presentation by CD8+ and CD4+ effector T cells?
Where are protein antigens of microbes concentrated after entering the body?
Where are protein antigens of microbes concentrated after entering the body?
What is the primary function of dendritic cells in T cell-dependent immune responses?
What is the primary function of dendritic cells in T cell-dependent immune responses?
What type of APC is responsible for presenting antigens to effector T cells in cell-mediated immune reactions?
What type of APC is responsible for presenting antigens to effector T cells in cell-mediated immune reactions?
Which type of T cells are reactivated by macrophages to induce killing of ingested microbes?
Which type of T cells are reactivated by macrophages to induce killing of ingested microbes?
What promotes the entry of naive T lymphocytes into the T cell zones of lymph nodes?
What promotes the entry of naive T lymphocytes into the T cell zones of lymph nodes?
How long does it take for a T cell response to begin in the lymph nodes after a microbial antigen is introduced at any site in the body?
How long does it take for a T cell response to begin in the lymph nodes after a microbial antigen is introduced at any site in the body?
Which type of T cells recognize peptide antigens displayed by MHC molecules of antigen-presenting cells?
Which type of T cells recognize peptide antigens displayed by MHC molecules of antigen-presenting cells?
What is the term for the property of T cells that requires them to recognize peptides only when displayed by an individual's MHC molecules?
What is the term for the property of T cells that requires them to recognize peptides only when displayed by an individual's MHC molecules?
Where are microbial antigens located in host cells that are recognized by CD8+ cytotoxic T lymphocytes?
Where are microbial antigens located in host cells that are recognized by CD8+ cytotoxic T lymphocytes?
What is the function of MHC molecules in the immune system?
What is the function of MHC molecules in the immune system?
What type of T cells recognize and respond to extracellular and intracellular microbes internalized into vesicular compartments in host cells?
What type of T cells recognize and respond to extracellular and intracellular microbes internalized into vesicular compartments in host cells?
What is the term for the process by which protein antigens are captured, broken down, and displayed for recognition by T lymphocytes?
What is the term for the process by which protein antigens are captured, broken down, and displayed for recognition by T lymphocytes?
