Immune Function Disorders Quiz
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Questions and Answers

What is the main cause of autoimmune diseases?

  • Overproduction of B cells
  • Deficiency of T cells
  • Decreased antibody production
  • Failure of self-tolerance mechanisms (correct)
  • Which of the following is an example of an autoimmune disease?

  • Psoriasis
  • Asthma
  • Influenza
  • Rheumatoid arthritis (correct)
  • What is the main effect of human immunodeficiency virus (HIV) on helper T cell count?

  • It has no effect on helper T cell count
  • It increases helper T cell count
  • It causes abnormal proliferation of helper T cells
  • It decreases helper T cell count (correct)
  • How is acquired immunodeficiency syndrome (AIDS) primarily transmitted?

    <p>Unprotected sexual contact or sharing needles with an infected person</p> Signup and view all the answers

    What are the three principal things that can go wrong with immune function?

    <p>Hypersensitivity, autoimmune diseases, and immunodeficiency diseases</p> Signup and view all the answers

    What is the specific cause of severe combined immunodeficiency disease (SCID)?

    <p>Genetic mutation affecting T and B lymphocytes</p> Signup and view all the answers

    What are the four types of hypersensitivity reactions, and what are their characteristics?

    <p>Immediate, delayed, cytotoxic, and immune complex; each involving different immunoglobulins and effector mechanisms</p> Signup and view all the answers

    What are the diseases to which a person with acquired immunodeficiency syndrome (AIDS) becomes more susceptible?

    <p>Pneumocystis pneumonia, Kaposi's sarcoma, and tuberculosis</p> Signup and view all the answers

    What is the main mode of action of the human immunodeficiency virus (HIV)?

    <p>Attacks and destroys white blood cells</p> Signup and view all the answers

    What normally prevents the occurrence of autoimmune diseases?

    <p>Regulation by suppressor T cells</p> Signup and view all the answers

    Which of the following best describes the pathology of acquired immunodeficiency syndrome (AIDS)?

    <p>Severe depletion of helper T cells and increased susceptibility to opportunistic infections</p> Signup and view all the answers

    What is the main cause of hypersensitivity reactions?

    <p>Excessive or inappropriate immune response to an antigen</p> Signup and view all the answers

    What is the specific cause of severe combined immunodeficiency disease (SCID)?

    <p>Defective gene that impairs the function of T cells and B cells</p> Signup and view all the answers

    Which of the following best describes the mode of action of human immunodeficiency virus (HIV)?

    <p>Attacks and destroys white blood cells, particularly helper T cells</p> Signup and view all the answers

    What is the main effect of hypersensitivity type I reaction on the body?

    <p>Release of histamine and other chemicals from mast cells and basophils</p> Signup and view all the answers

    What is the primary cause of autoimmune diseases?

    <p>Loss of tolerance to self-antigens, leading to immune attack on the body's own tissues</p> Signup and view all the answers

    What is the role of MHC-II proteins in the response of an immunocompetent B cell to a foreign antigen?

    <p>Activating the B cell to undergo clonal selection</p> Signup and view all the answers

    What distinguishes a plasma cell from a B cell?

    <p>Plasma cells produce antibodies while B cells do not</p> Signup and view all the answers

    How do antibodies combat antigens by opsonization?

    <p>By coating the antigens to make them more susceptible to phagocytosis</p> Signup and view all the answers

    What is the role of MHC-II proteins in the response of an immunocompetent B cell to a foreign antigen?

    <p>Bind to the antigen and present it to T helper cells</p> Signup and view all the answers

    What is the main difference between a plasma cell and a B cell?

    <p>Plasma cells have a longer lifespan than B cells</p> Signup and view all the answers

    How do antibodies combat antigens by opsonization?

    <p>By binding to the antigens and making them more attractive to phagocytic cells</p> Signup and view all the answers

    How do antibodies combat antigens through neutralization?

    <p>By binding to the antigens and blocking their activity</p> Signup and view all the answers

    What is the main role of a TH cell in the response of an immunocompetent B cell to a foreign antigen?

    <p>Activating the B cell to undergo clonal selection and differentiation</p> Signup and view all the answers

    What distinguishes a plasma cell from a memory B cell?

    <p>Plasma cells are short-lived, while memory B cells are long-lived</p> Signup and view all the answers

    What is the function of an antigen-presenting cell (APC) when it detects a foreign antigen?

    <p>It presents the foreign antigen to T cells</p> Signup and view all the answers

    What are the functional differences between MHC-I and MHC-II proteins?

    <p>MHC-I presents endogenous antigens, while MHC-II presents exogenous antigens</p> Signup and view all the answers

    What is the main role of activated TH cells in cellular immunity?

    <p>Stimulate other immune cells like neutrophils and macrophages</p> Signup and view all the answers

    What are the characteristics of immune memory in cellular immunity?

    <p>It results in an immediate and stronger response upon re-exposure to the same antigen</p> Signup and view all the answers

    What are the three fundamental stages of cellular immunity?

    <p>Antigen recognition, costimulation, and clonal selection of a T cell, differentiation of selected T cells into effector cells and memory cells</p> Signup and view all the answers

    How do activated TH cells stimulate neutrophils, NK cells, and macrophages in cellular immunity?

    <p>By releasing cytokines such as interferons and tumor necrosis factor</p> Signup and view all the answers

    What is the role of MHC-I proteins in cellular immunity?

    <p>Recognition of antigens by cytotoxic T cells</p> Signup and view all the answers

    What are the characteristics of immune memory in cellular immunity?

    <p>Enhanced responsiveness to previously encountered antigens</p> Signup and view all the answers

    What is the main function of antigen-presenting cells (APCs) in cellular immunity?

    <p>Activating T cells by presenting antigens</p> Signup and view all the answers

    What is the primary function of activated cytotoxic T (TC) cells in cellular immunity?

    <p>Destroying target cells</p> Signup and view all the answers

    What is the significance of MHC restriction in cellular immunity?

    <p>It ensures that T cells only recognize foreign antigens presented with MHC proteins</p> Signup and view all the answers

    What is the role of activated helper T (TH) cells in cellular immunity?

    <p>Stimulating neutrophils, NK cells, and macrophages</p> Signup and view all the answers

    What are the three fundamental stages of cellular immunity?

    <p>Antigen presentation, costimulation, and T cell activation</p> Signup and view all the answers

    How do activated cytotoxic T (TC) cells destroy target cells in cellular immunity?

    <p>Release of perforin and granzymes</p> Signup and view all the answers

    What is the role of antigen-presenting cells (APCs) when they detect a foreign antigen?

    <p>Presentation of the foreign antigen to T cells</p> Signup and view all the answers

    What is the functional difference between MHC-I and MHC-II proteins in cellular immunity?

    <p>MHC-I presents endogenous antigens while MHC-II presents exogenous antigens</p> Signup and view all the answers

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