Podcast
Questions and Answers
Which type of immune deficiency is characterized by a single nucleotide mis-sense mutation in the beta-2 Integrin gene?
Which type of immune deficiency is characterized by a single nucleotide mis-sense mutation in the beta-2 Integrin gene?
- Primary immune deficiency
- Secondary immune deficiency
- SCID
- Canine leukocyte Adhesion Deficiency (correct)
What is the main difference between primary and secondary immune deficiencies?
What is the main difference between primary and secondary immune deficiencies?
- Primary immune deficiencies are more common than secondary immune deficiencies
- Primary immune deficiencies are caused by pathogens, while secondary immune deficiencies are caused by cytokine signaling
- Primary immune deficiencies are inherited, while secondary immune deficiencies are not (correct)
- Primary immune deficiencies are treatable, while secondary immune deficiencies are not
What is the most common cause of secondary immune deficiency?
What is the most common cause of secondary immune deficiency?
- Pathogens
- Age
- Cytokine signaling
- Chronic disease (correct)
Which type of immune deficiency is clinically apparent in early life and has an increased mortality chance?
Which type of immune deficiency is clinically apparent in early life and has an increased mortality chance?
What is the characteristic feature of Canine leukocyte Adhesion Deficiency (CLAD)?
What is the characteristic feature of Canine leukocyte Adhesion Deficiency (CLAD)?
Which breed is commonly affected by Canine leukocyte Adhesion Deficiency (CLAD)?
Which breed is commonly affected by Canine leukocyte Adhesion Deficiency (CLAD)?
What is the main function of white blood cells in the immune system?
What is the main function of white blood cells in the immune system?
What does persistent neutrophilia indicate in Canine leukocyte Adhesion Deficiency (CLAD)?
What does persistent neutrophilia indicate in Canine leukocyte Adhesion Deficiency (CLAD)?
Which type of immune deficiency is caused by a mutation in a gene associated with the immune response?
Which type of immune deficiency is caused by a mutation in a gene associated with the immune response?
What is the likelihood of finding Canine leukocyte Adhesion Deficiency (CLAD) in a clinic?
What is the likelihood of finding Canine leukocyte Adhesion Deficiency (CLAD) in a clinic?
Which breed is affected by a mutation for key cytokines (IL-2, 4, 7, 9, 15) leading to immune system failure?
Which breed is affected by a mutation for key cytokines (IL-2, 4, 7, 9, 15) leading to immune system failure?
Which breed is affected by a mutation for lymphocyte formation inhibiting the immune response once maternal immunity has waned?
Which breed is affected by a mutation for lymphocyte formation inhibiting the immune response once maternal immunity has waned?
Which breed is affected by a mutation impacting T & B cell receptors, inhibiting somatic mutation to different antigens, and has a clinical diagnosis that is not straightforward?
Which breed is affected by a mutation impacting T & B cell receptors, inhibiting somatic mutation to different antigens, and has a clinical diagnosis that is not straightforward?
Which factor may not be a useful marker for immunodeficiency syndromes?
Which factor may not be a useful marker for immunodeficiency syndromes?
Which factor is associated with age-related decline in immune function?
Which factor is associated with age-related decline in immune function?
Which factor can suppress the immune response and increase infection susceptibility?
Which factor can suppress the immune response and increase infection susceptibility?
What might be the underlying cause if an animal shows reduced concentrations of cytokines and reduced T lymphocyte function?
What might be the underlying cause if an animal shows reduced concentrations of cytokines and reduced T lymphocyte function?
Which type of immune deficiency is characterized by a single nucleotide mis-sense mutation in the beta-2 Integrin gene?
Which type of immune deficiency is characterized by a single nucleotide mis-sense mutation in the beta-2 Integrin gene?
Which factor can suppress the immune response and increase infection susceptibility?
Which factor can suppress the immune response and increase infection susceptibility?
Which breed is affected by a mutation for key cytokines (IL-2, 4, 7, 9, 15) leading to immune system failure?
Which breed is affected by a mutation for key cytokines (IL-2, 4, 7, 9, 15) leading to immune system failure?
What is the main function of white blood cells in the immune system?
What is the main function of white blood cells in the immune system?
What is the likelihood of finding Canine leukocyte Adhesion Deficiency (CLAD) in a clinic?
What is the likelihood of finding Canine leukocyte Adhesion Deficiency (CLAD) in a clinic?
What is the characteristic feature of Canine leukocyte Adhesion Deficiency (CLAD)?
What is the characteristic feature of Canine leukocyte Adhesion Deficiency (CLAD)?
What is the most common cause of secondary immune deficiency?
What is the most common cause of secondary immune deficiency?
What are the breed-specific mutations associated with Severe Combined Immunodeficiency (SCID) in dogs and horses?
What are the breed-specific mutations associated with Severe Combined Immunodeficiency (SCID) in dogs and horses?
What are the clinical manifestations of Severe Combined Immunodeficiency (SCID) in Arabian horses?
What are the clinical manifestations of Severe Combined Immunodeficiency (SCID) in Arabian horses?
What are the potential causes of lymphopenia?
What are the potential causes of lymphopenia?
What are the secondary immune deficiencies discussed in the text?
What are the secondary immune deficiencies discussed in the text?
What factors can suppress the immune response and increase infection susceptibility?
What factors can suppress the immune response and increase infection susceptibility?
What factors can increase immune function?
What factors can increase immune function?
What is the significance of reduced concentrations of cytokines and reduced T lymphocyte function?
What is the significance of reduced concentrations of cytokines and reduced T lymphocyte function?
What should be considered if an animal shows recurrent infections, neutrophilia or lymphopenia, and susceptibility to infection?
What should be considered if an animal shows recurrent infections, neutrophilia or lymphopenia, and susceptibility to infection?
