Imaging and Serum Analysis in Bone Disease
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Imaging and Serum Analysis in Bone Disease

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Questions and Answers

What is the best imaging technique for assessing the extent of bone disease?

  • Low-dose WB-CT or PET/CT (correct)
  • Conventional skeletal survey
  • MRI
  • X-ray imaging
  • When is MRI particularly useful in skeletal assessments?

  • To measure serum CrossLaps levels
  • To rule out focal bone marrow lesions (correct)
  • To determine bone density
  • To visualize joint spaces
  • Why is a conventional skeletal survey recommended only when other imaging resources are unavailable?

  • It is less sensitive than low-dose WB-CT and PET/CT. (correct)
  • It has a higher sensitivity than MRI.
  • It is the most advanced imaging technique.
  • It provides better detail of bone marrow lesions.
  • What does Serum CrossLaps (CTX) help assess?

    <p>Bone turnover and bisphosphonate therapy adequacy</p> Signup and view all the answers

    What does the presence of SMM indicated by MRI suggest?

    <p>It may indicate the potential for cord compression.</p> Signup and view all the answers

    Study Notes

    Imaging Study for Bone Disease

    • Bone disease extent best assessed by low-dose WB-CT or PET/CT scans
    • MRI useful for patients with suspected bone marrow lesions, ruling out focal lesions
    • MRI also useful for assessing extramedullary disease and suspected cord compression needing detailed imaging
    • Conventional skeletal surveys less sensitive than low-dose scans, recommended only when advanced imaging unavailable

    Serum CrossLaps

    • Serum CrossLaps (CTX) useful in assessing bone turnover
    • Used to determine adequacy of bisphosphonate therapy

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    Description

    This quiz covers imaging techniques and serum markers for assessing bone disease. It highlights the effectiveness of low-dose WB-CT and PET/CT scans, as well as the role of MRI in diagnosing bone marrow lesions. Additionally, it discusses the use of Serum CrossLaps in evaluating bone turnover and bisphosphonate therapy adequacy.

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