Imaging and Serum Analysis in Bone Disease

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Questions and Answers

What is the best imaging technique for assessing the extent of bone disease?

Low-dose WB-CT or PET/CT (correct)
Conventional skeletal survey
MRI
X-ray imaging

When is MRI particularly useful in skeletal assessments?

To measure serum CrossLaps levels
To rule out focal bone marrow lesions (correct)
To determine bone density
To visualize joint spaces

Why is a conventional skeletal survey recommended only when other imaging resources are unavailable?

It is less sensitive than low-dose WB-CT and PET/CT. (correct)
It has a higher sensitivity than MRI.
It is the most advanced imaging technique.
It provides better detail of bone marrow lesions.

What does Serum CrossLaps (CTX) help assess?

<p>Bone turnover and bisphosphonate therapy adequacy (A)</p> Signup and view all the answers

What does the presence of SMM indicated by MRI suggest?

<p>It may indicate the potential for cord compression. (B)</p> Signup and view all the answers

Flashcards

Bone disease assessment

The severity of bone disease is best determined by low-dose WB-CT or PET/CT scans.

MRI for skeletal marrow

MRI helps find focal bone marrow lesions (before bone disease is obvious), extramedullary diseases, and possible spinal cord problems (when specific area is needed).

MRI findings

MRI can show bone marrow issues that might be coming before obvious disease changes, other diseases outside the bone marrow, problems pressing on the spinal cord.

Conventional skeletal survey

X-rays of the skeleton; less detailed than advanced imaging.

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Skeletal survey sensitivity

Less effective at finding bone problems compared to newer imaging methods.

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Serum CrossLaps (CTX)

Blood test to measure bone breakdown and asses if medication is working correctly.

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Skeletal survey images

X-ray images of the skeleton provide view of potential abnormalities in bones.

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Study Notes

Imaging Study for Bone Disease

Bone disease extent best assessed by low-dose WB-CT or PET/CT scans
MRI useful for patients with suspected bone marrow lesions, ruling out focal lesions
MRI also useful for assessing extramedullary disease and suspected cord compression needing detailed imaging
Conventional skeletal surveys less sensitive than low-dose scans, recommended only when advanced imaging unavailable