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Imaging and Serum Analysis in Bone Disease

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Imaging and Serum Analysis in Bone Disease

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Questions and Answers

What is the best imaging technique for assessing the extent of bone disease?

Low-dose WB-CT or PET/CT (correct)

Conventional skeletal survey

MRI

X-ray imaging

When is MRI particularly useful in skeletal assessments?

To measure serum CrossLaps levels

To rule out focal bone marrow lesions (correct)

To determine bone density

To visualize joint spaces

Why is a conventional skeletal survey recommended only when other imaging resources are unavailable?

It is less sensitive than low-dose WB-CT and PET/CT. (correct)

It has a higher sensitivity than MRI.

It is the most advanced imaging technique.

It provides better detail of bone marrow lesions.

What does Serum CrossLaps (CTX) help assess?

<p>Bone turnover and bisphosphonate therapy adequacy</p> Signup and view all the answers

What does the presence of SMM indicated by MRI suggest?

<p>It may indicate the potential for cord compression.</p> Signup and view all the answers

Study Notes

Imaging Study for Bone Disease

Bone disease extent best assessed by low-dose WB-CT or PET/CT scans
MRI useful for patients with suspected bone marrow lesions, ruling out focal lesions
MRI also useful for assessing extramedullary disease and suspected cord compression needing detailed imaging
Conventional skeletal surveys less sensitive than low-dose scans, recommended only when advanced imaging unavailable

Serum CrossLaps

Serum CrossLaps (CTX) useful in assessing bone turnover
Used to determine adequacy of bisphosphonate therapy

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Description

This quiz covers imaging techniques and serum markers for assessing bone disease. It highlights the effectiveness of low-dose WB-CT and PET/CT scans, as well as the role of MRI in diagnosing bone marrow lesions. Additionally, it discusses the use of Serum CrossLaps in evaluating bone turnover and bisphosphonate therapy adequacy.