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Imaging and Markers for Bone Disease

Created by

@RosyDiction

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Questions and Answers

What is the preferred imaging technique for assessing the extent of bone disease?

MRI of the entire body

Ultrasound examination

Low-dose WB-CT or PET/CT (correct)

Conventional skeletal survey

In which scenario is an MRI particularly useful?

When ruling out focal bone marrow lesions in suspected SMM (correct)

For assessing general bone density

To evaluate the entire skeletal system

For routine cancer screening

Why is a conventional skeletal survey recommended only when more advanced imaging resources are unavailable?

It cannot assess the effect of bisphosphonate therapy

It is less sensitive in detecting bone disease (correct)

It provides only static images with no functional assessment

It has a higher cost than WB-CT and PET/CT

What role do Serum CrossLaps (CTX) play in the assessment of bone health?

<p>They are used to assess bone turnover</p> Signup and view all the answers

What can MRI findings indicate in the context of skeletal health?

<p>SMM possibly leading to bone lesions and cord compression</p> Signup and view all the answers

Study Notes

Imaging Study for Bone Disease

Low-dose WB-CT or PET/CT scans best assess the extent of bone disease
MRI scans helpful for suspected bone marrow lesions (before true osteolytic disease occurs) and extramedullary disease (when detailed imaging needed)
MRI useful for assessing cord compression

Conventional Skeletal Survey

Less sensitive than low-dose WB-CT or PET/CT imaging
Recommended only if advanced imaging resources are unavailable

Serum Markers

Serum CrossLaps (CTX) useful in assessing bone turnover and determining adequacy of bisphosphonate therapy.

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Description

This quiz focuses on the best imaging techniques for assessing bone disease, including the roles of low-dose whole-body CT, PET/CT scans, and MRI. It also covers the significance of serum markers like CrossLaps in evaluating bone turnover and treatment efficacy. Test your knowledge on these essential diagnostics in bone disease management.