Imaging and Markers for Bone Disease
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Questions and Answers

What is the preferred imaging technique for assessing the extent of bone disease?

  • MRI of the entire body
  • Ultrasound examination
  • Low-dose WB-CT or PET/CT (correct)
  • Conventional skeletal survey
  • In which scenario is an MRI particularly useful?

  • When ruling out focal bone marrow lesions in suspected SMM (correct)
  • For assessing general bone density
  • To evaluate the entire skeletal system
  • For routine cancer screening
  • Why is a conventional skeletal survey recommended only when more advanced imaging resources are unavailable?

  • It cannot assess the effect of bisphosphonate therapy
  • It is less sensitive in detecting bone disease (correct)
  • It provides only static images with no functional assessment
  • It has a higher cost than WB-CT and PET/CT
  • What role do Serum CrossLaps (CTX) play in the assessment of bone health?

    <p>They are used to assess bone turnover</p> Signup and view all the answers

    What can MRI findings indicate in the context of skeletal health?

    <p>SMM possibly leading to bone lesions and cord compression</p> Signup and view all the answers

    Study Notes

    Imaging Study for Bone Disease

    • Low-dose WB-CT or PET/CT scans best assess the extent of bone disease
    • MRI scans helpful for suspected bone marrow lesions (before true osteolytic disease occurs) and extramedullary disease (when detailed imaging needed)
    • MRI useful for assessing cord compression

    Conventional Skeletal Survey

    • Less sensitive than low-dose WB-CT or PET/CT imaging
    • Recommended only if advanced imaging resources are unavailable

    Serum Markers

    • Serum CrossLaps (CTX) useful in assessing bone turnover and determining adequacy of bisphosphonate therapy.

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    Description

    This quiz focuses on the best imaging techniques for assessing bone disease, including the roles of low-dose whole-body CT, PET/CT scans, and MRI. It also covers the significance of serum markers like CrossLaps in evaluating bone turnover and treatment efficacy. Test your knowledge on these essential diagnostics in bone disease management.

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