Imaging and Markers for Bone Disease

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson
Download our mobile app to listen on the go
Get App

Questions and Answers

What is the preferred imaging technique for assessing the extent of bone disease?

  • MRI of the entire body
  • Ultrasound examination
  • Low-dose WB-CT or PET/CT (correct)
  • Conventional skeletal survey

In which scenario is an MRI particularly useful?

  • When ruling out focal bone marrow lesions in suspected SMM (correct)
  • For assessing general bone density
  • To evaluate the entire skeletal system
  • For routine cancer screening

Why is a conventional skeletal survey recommended only when more advanced imaging resources are unavailable?

  • It cannot assess the effect of bisphosphonate therapy
  • It is less sensitive in detecting bone disease (correct)
  • It provides only static images with no functional assessment
  • It has a higher cost than WB-CT and PET/CT

What role do Serum CrossLaps (CTX) play in the assessment of bone health?

<p>They are used to assess bone turnover (B)</p> Signup and view all the answers

What can MRI findings indicate in the context of skeletal health?

<p>SMM possibly leading to bone lesions and cord compression (C)</p> Signup and view all the answers

Flashcards

Bone disease assessment

Best assessed by low-dose WB-CT or PET/CT imaging.

MRI use (skeletal)

Useful to rule out focal bone marrow lesions in suspected SMM, and assess extramedullary diseases/cord compression.

Skeletal survey sensitivity

Less sensitive than WB-CT/PET/CT for bone disease.

Skeletal survey recommendation

Recommended only when advanced imaging isn't available.

Signup and view all the flashcards

Serum CrossLaps (CTX) use

Assesses bone turnover and bisphosphonate therapy adequacy.

Signup and view all the flashcards

Low-dose WB-CT

A type of X-ray used to quickly visualize the entire skeletal system to assess bone issues.

Signup and view all the flashcards

PET/CT imaging

A sophisticated imaging method combining positron emission tomography (PET) and computed tomography (CT) for precise assessments of bone and other tissues.

Signup and view all the flashcards

MRI findings (skeletal)

MRI can detect skeletal marrow (SMM) involvement (before bone lesions), extramedullary disease (EMD), and potential cord compression.

Signup and view all the flashcards

Study Notes

Imaging Study for Bone Disease

  • Low-dose WB-CT or PET/CT scans best assess the extent of bone disease
  • MRI scans helpful for suspected bone marrow lesions (before true osteolytic disease occurs) and extramedullary disease (when detailed imaging needed)
  • MRI useful for assessing cord compression

Conventional Skeletal Survey

  • Less sensitive than low-dose WB-CT or PET/CT imaging
  • Recommended only if advanced imaging resources are unavailable

Serum Markers

  • Serum CrossLaps (CTX) useful in assessing bone turnover and determining adequacy of bisphosphonate therapy.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

More Like This

Use Quizgecko on...
Browser
Open
Browser
Browser