Questions and Answers
What is the brand name of Ibandronate Sodium?
What are the dosage forms of Ibandronate Sodium?
What are the tablet strengths of Ibandronate?
2.5 and 150mg
What is the strength of Ibandronate injection?
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What is the indication for Ibandronate?
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What is the daily oral dose of Ibandronate?
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What is the monthly oral dose of Ibandronate?
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What drug class does Ibandronate belong to?
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When should Ibandronate tablets be taken?
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What should patients not do following each dose of Ibandronate?
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What is the dose for Ibandronate injection?
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What does Ibandronate inhibit?
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What drug interactions should be noted with Ibandronate?
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In which patients is Ibandronate contraindicated?
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Oral bisphosphonates have been associated with what conditions?
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In which patients is Ibandronate not recommended?
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Study Notes
Ibandronate Sodium Overview
- Brand name for ibandronate sodium: Boniva.
- Available dosage forms: Tablets and injections.
Dosage Strengths
- Tablet strengths available: 2.5 mg and 150 mg.
- Injection strength: 1 mg/ml in 5 ml single-use prefilled syringes.
Indications
- Primarily indicated for the treatment and prevention of osteoporosis in postmenopausal women.
Dosage Regimens
- Daily oral dosage: 2.5 mg.
- Monthly oral dosage: 150 mg.
- Intravenous injection dosage: 3 mg administered over 15-30 seconds every 3 months.
Administration Guidelines
- Tablets should be taken 60 minutes before any food or non-water drinks and before other oral medications or supplements.
- Patients should remain upright and not lie down or recline for 60 minutes after taking each dose.
Mechanism of Action
- Ibandronate inhibits osteoclast-mediated bone resorption, helping to maintain bone density.
Drug Interactions
- Calcium and antacids can reduce absorption if consumed within 60 minutes of taking oral ibandronate.
Contraindications
- Not suitable for individuals with uncorrected hypocalcemia or those who cannot sit or stand upright for an hour.
Associated Risks
- Oral bisphosphonates, including ibandronate, are linked to dysphagia, esophagitis, and esophageal or gastric ulcers.
- Not recommended for patients with severe renal impairment (reduce creatinine clearance).
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Test your knowledge on Ibandronate Sodium with these flashcards. Learn about its brand name, dosage forms, strengths, and indications. Perfect for anyone studying osteoporosis treatment and prevention.