Ibandronate Sodium Flashcards
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Questions and Answers

What is the brand name of Ibandronate Sodium?

  • Boniva (correct)
  • Tablet
  • Injection
  • Osteoporosis
  • What are the dosage forms of Ibandronate Sodium?

  • Injection (correct)
  • Capsule
  • Tablet (correct)
  • Syringe
  • What are the tablet strengths of Ibandronate?

    2.5 and 150mg

    What is the strength of Ibandronate injection?

    <p>1mg/ml in 5ml single use prefilled syringes</p> Signup and view all the answers

    What is the indication for Ibandronate?

    <p>for treatment and prevention of osteoporosis in postmenopausal women</p> Signup and view all the answers

    What is the daily oral dose of Ibandronate?

    <p>2.5mg</p> Signup and view all the answers

    What is the monthly oral dose of Ibandronate?

    <p>150mg</p> Signup and view all the answers

    What drug class does Ibandronate belong to?

    <p>osteoporosis agent</p> Signup and view all the answers

    When should Ibandronate tablets be taken?

    <p>60 minutes before the first food or non-water drink of the day</p> Signup and view all the answers

    What should patients not do following each dose of Ibandronate?

    <p>lie down or recline for 60 minutes</p> Signup and view all the answers

    What is the dose for Ibandronate injection?

    <p>3mg given intravenously over 15-30 seconds every 3 months</p> Signup and view all the answers

    What does Ibandronate inhibit?

    <p>osteoclast mediated bone resorption</p> Signup and view all the answers

    What drug interactions should be noted with Ibandronate?

    <p>calcium and antacids may decrease absorption if taken within 60 minutes of oral Ibandronate</p> Signup and view all the answers

    In which patients is Ibandronate contraindicated?

    <p>with uncorrected hypocalcemia, who cannot sit or stand upright for an hour</p> Signup and view all the answers

    Oral bisphosphonates have been associated with what conditions?

    <p>dysphagia, esophagitis, and esophageal or gastric ulcers</p> Signup and view all the answers

    In which patients is Ibandronate not recommended?

    <p>severe renal impairment</p> Signup and view all the answers

    Study Notes

    Ibandronate Sodium Overview

    • Brand name for ibandronate sodium: Boniva.
    • Available dosage forms: Tablets and injections.

    Dosage Strengths

    • Tablet strengths available: 2.5 mg and 150 mg.
    • Injection strength: 1 mg/ml in 5 ml single-use prefilled syringes.

    Indications

    • Primarily indicated for the treatment and prevention of osteoporosis in postmenopausal women.

    Dosage Regimens

    • Daily oral dosage: 2.5 mg.
    • Monthly oral dosage: 150 mg.
    • Intravenous injection dosage: 3 mg administered over 15-30 seconds every 3 months.

    Administration Guidelines

    • Tablets should be taken 60 minutes before any food or non-water drinks and before other oral medications or supplements.
    • Patients should remain upright and not lie down or recline for 60 minutes after taking each dose.

    Mechanism of Action

    • Ibandronate inhibits osteoclast-mediated bone resorption, helping to maintain bone density.

    Drug Interactions

    • Calcium and antacids can reduce absorption if consumed within 60 minutes of taking oral ibandronate.

    Contraindications

    • Not suitable for individuals with uncorrected hypocalcemia or those who cannot sit or stand upright for an hour.

    Associated Risks

    • Oral bisphosphonates, including ibandronate, are linked to dysphagia, esophagitis, and esophageal or gastric ulcers.
    • Not recommended for patients with severe renal impairment (reduce creatinine clearance).

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    Description

    Test your knowledge on Ibandronate Sodium with these flashcards. Learn about its brand name, dosage forms, strengths, and indications. Perfect for anyone studying osteoporosis treatment and prevention.

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