Ibandronate Flashcards

Questions and Answers

What is the brand name for ibandronate?

Vitamin D

Boniva (correct)

Osteoporosis

Calcium

What is the functional class of ibandronate?

Bone-reabsorption inhibitor, electrolyte modifier

What chemical class does ibandronate belong to?

Bisphosphonate

What are the uses of ibandronate?

Postmenopausal osteoporosis and prophylaxis Signup and view all the answers

What is the therapeutic outcome of ibandronate?

Increased bone mineral density Signup and view all the answers

What is the onset of action for ibandronate?

Unknown Signup and view all the answers

What is the peak time for ibandronate?

0.5-2 hr Signup and view all the answers

What is the duration of effect for ibandronate?

Up to 1 month Signup and view all the answers

What are the contraindications for ibandronate?

Achalasia, esophageal stricture, hypocalcemia, renal failure, hypersensitivity to bisphosphonates, inability to stand or sit upright Signup and view all the answers

What precautions should be taken when using ibandronate?

Pregnancy, breastfeeding, children, geriatric, chemo, coagulopathy, dental disease, diabetes mellitus, dysphagia, GERD, multiple myeloma, GI/renal disease, vitamin D deficiency, hypertension, infection, phosphate hypersensitivity Signup and view all the answers

What is the normal dosage for adult patients taking ibandronate?

150 mg orally per month or IV bolus 3 mg every 3 months Signup and view all the answers

What are some adverse effects of ibandronate?

Fever, insomnia, dizziness, headache, hypertension, atrial fibrillation, ocular pain/itis, esophageal ulcer, constipation, nausea, vomiting, diarrhea, dyspepsia, rash, hypomagnesemia, hypophosphatemia, hypocalcemia, hypercholesterolemia, bone pain, myalgia, osteonecrosis of the jaw, Stevens-Johnson syndrome, erythema multiforme, dermatitis bullous, anaphylaxis Signup and view all the answers

What lab values might be affected by ibandronate?

Decreased alk phos, magnesium, calcium, phosphate; increased cholesterol Signup and view all the answers

What nursing assessments are important for patients on ibandronate?

Osteoporosis, bone mineral density, electrolytes, anaphylaxis, dental health, bone pain, esophageal irritation/ulcers, heartburn/swallowing issues, oral assessment Signup and view all the answers

What are the implementation instructions for ibandronate?

Give early in the morning with 8 oz water, keep patient upright for >1 hr, do not suck/chew, store at room temperature Signup and view all the answers

What patient education should be provided for those taking ibandronate?

Report hypercalcemia symptoms, continue dietary requirements, take analgesics for bone pain, report vision symptoms, and adhere to medication schedule Signup and view all the answers

Study Notes

Ibandronate Overview

Ibandronate is a bisphosphonate medication marketed under the brand name Boniva.
Functions as a bone-reabsorption inhibitor and electrolyte modifier.

Indications

Primarily used for treating postmenopausal osteoporosis and as a preventative measure against it.

Therapeutic Effects

Aims to increase bone mineral density, contributing to better overall bone health.

Pharmacokinetics

Onset of action is currently unknown.
Peak plasma concentration occurs within 0.5 to 2 hours after administration.
Duration of effect can last up to 1 month.

Contraindications

Not advisable for patients with achalasia, esophageal stricture, hypocalcemia, renal failure, or hypersensitivity to bisphosphonates.
Individuals who are unable to stand or sit upright for at least 60 minutes should avoid use.

Precautions

Care should be taken in pregnant or breastfeeding women, children, geriatrics, patients undergoing chemotherapy, and those with coagulopathy.
Other conditions requiring caution include dental disease, diabetes mellitus, GERD, multiple myeloma, and renal issues.

Dosage Information

Recommended oral dosage for adults is 150 mg once a month.
Intravenous bolus recommended dosage is 3 mg every three months.

Adverse Effects

Common side effects include fever, insomnia, dizziness, headache, and hypertension.
Serious adverse effects can include esophageal ulceration, hypomagnesemia, osteonecrosis of the jaw, and severe skin reactions such as Stevens-Johnson syndrome.

Laboratory Monitoring

Monitor for decreased levels of alkaline phosphatase, magnesium, calcium, and phosphate.
May see increased cholesterol levels during treatment.

Nursing Considerations

Assess for osteoporosis, bone mineral density, and electrolyte levels.
Observe for signs of anaphylaxis and evaluate dental health regularly.
Monitor for symptoms of bone pain and esophageal irritation/ulcers.

Administration Guidelines

Administer early in the morning with 8 oz of water.
Ensure patient remains upright for at least 1 hour post-administration.
Store medication at room temperature and avoid chewing or sucking the tablet.

Patient Education

Instruct patients to recognize hypercalcemia symptoms (e.g., nausea, unusual muscle activity, severe diarrhea).
Encourage increased intake of vitamin D, calcium, and phosphate through diet.
Advise on taking analgesics for bone pain and suggest small, frequent meals to alleviate nausea.
Emphasize the importance of reporting any dental issues, maintaining an upright position after taking the medication, and adhering to the monthly dosing schedule.
Advise patients to inform healthcare providers about pregnancy or breastfeeding status.

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Description

Test your knowledge on ibandronate with these flashcards, covering its definitions, classes, uses, and outcomes. Ideal for students in pharmacology or healthcare fields, these cards provide a concise overview of this important medication for osteoporosis treatment.