Hysterectomy Approaches Overview
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Questions and Answers

What is the primary advantage of the vaginal approach for hysterectomy?

  • Decreased morbidity and mortality (correct)
  • Higher complication rates
  • Less visibility during the procedure
  • Increased surgical duration
  • Which factors may limit the use of the vaginal approach for hysterectomy?

  • Patient age and previous surgeries
  • Cost of the procedure
  • Surgeon's preference and training
  • Uterine size and pelvic adhesions (correct)
  • What distinguishes a radical hysterectomy from a total hysterectomy?

  • Only performed on younger patients
  • Involves removal of surrounding parametrial tissues (correct)
  • Removal of only the uterine cervix
  • Presence of fallopian tubes is crucial
  • Which surgical technique includes both laparoscopic and vaginal approaches?

    <p>Laparoscopic-assisted vaginal hysterectomy (LAVH)</p> Signup and view all the answers

    What is the main reason for preferring a total hysterectomy over a subtotal hysterectomy?

    <p>Decreased possibility of cervical cancer</p> Signup and view all the answers

    In what position is the patient placed for a vaginal hysterectomy?

    <p>Dorsal lithotomy with head-down tilt</p> Signup and view all the answers

    Which characteristic of the abdominal approach for hysterectomy is accurate?

    <p>Performed with the patient in a supine position</p> Signup and view all the answers

    What surgical approaches can be categorized under abdominal hysterectomy?

    <p>Total, subtotal, and radical</p> Signup and view all the answers

    Which of the following is a common emotional response patients may experience before gynecologic procedures?

    <p>Fear</p> Signup and view all the answers

    What physiologic change is caused by the creation of pneumoperitoneum using carbon dioxide during laparoscopic procedures?

    <p>Impaired cardiac function</p> Signup and view all the answers

    Which of the following complications is NOT typically associated with laparoscopic hysterectomy?

    <p>Postoperative infection</p> Signup and view all the answers

    What is one of the most common symptoms associated with uterine fibroids?

    <p>Menorrhagia</p> Signup and view all the answers

    What is the typical age threshold at which a bilateral salpingooophorectomy (BSO) is performed alongside hysterectomy to reduce ovarian cancer risk?

    <p>45 years</p> Signup and view all the answers

    In which uterine location do fibroids NOT develop?

    <p>Extraglandular</p> Signup and view all the answers

    What is a potential consequence of nerve injuries during a hysterectomy?

    <p>Chronic pain</p> Signup and view all the answers

    Which hormone is speculated to play a role in the growth of uterine fibroids?

    <p>Estrogen</p> Signup and view all the answers

    What is the primary reason for using neuromuscular blockade during a laparoscopic hysterectomy?

    <p>To allow for greater abdominal insufflation</p> Signup and view all the answers

    Which disadvantage is primarily associated with the use of nitrous oxide during laparoscopic hysterectomy?

    <p>Potential bowel distension leading to reduced surgical access</p> Signup and view all the answers

    Why is there controversy surrounding the use of nitrous oxide in laparoscopic surgeries?

    <p>Scientific data linking it to specific intraoperative complications is limited</p> Signup and view all the answers

    What is a key factor contributing to improved surgical visualization during laparoscopic hysterectomy?

    <p>Neuromuscular blockade that reduces intraabdominal pressures</p> Signup and view all the answers

    Which statement best describes the role of the anesthesia provider in determining the use of nitrous oxide during laparoscopic hysterectomy?

    <p>The choice to include or omit nitrous oxide depends on the individual provider's judgment.</p> Signup and view all the answers

    What psychological factors may affect a patient undergoing hysterectomy?

    <p>Concerns about postoperative pain management and disfigurement</p> Signup and view all the answers

    Which of the following is a primary advantage of regional anesthesia over general anesthesia in hysterectomy?

    <p>Quicker recovery time and decreased incidence of PONV</p> Signup and view all the answers

    What is a significant concern when using spinal anesthesia in younger patients prior to hysterectomy?

    <p>Increased propensity for post dural puncture headache (PDPH)</p> Signup and view all the answers

    Which sensory dermatome level is recommended to block for adequate anesthesia during uterine procedures?

    <p>T4-T6</p> Signup and view all the answers

    Which factor may limit the use of regional anesthesia in hysterectomy patients?

    <p>Nature of the surgical procedure being performed</p> Signup and view all the answers

    What is a potential emotional response related to a patient's cultural background impacting their hysterectomy experience?

    <p>Guilt and shame regarding reproductive decisions</p> Signup and view all the answers

    Why might a provider opt for a combined spinal-epidural (CSE) anesthesia technique?

    <p>To achieve a faster onset of pain relief while maintaining flexibility</p> Signup and view all the answers

    Which statement correctly identifies a psychological concern that may arise in female patients regarding hysterectomy?

    <p>Concerns about the potential impact on sexual function and desirability</p> Signup and view all the answers

    What is a potential risk for patients with peripheral vascular insufficiency when positioned in lithotomy?

    <p>Development of venous stasis</p> Signup and view all the answers

    Which physiological change is likely to occur when a patient is in the lithotomy position during surgery?

    <p>Elevated pulmonary artery pressure</p> Signup and view all the answers

    What complication may arise for obese patients in the lithotomy position combined with Trendelenburg?

    <p>Atelectasis due to V/Q mismatching</p> Signup and view all the answers

    How does lowering the legs from the lithotomy position to supine typically affect blood volume distribution?

    <p>Blood volume is redistributed leading to hypotension</p> Signup and view all the answers

    What is commonly the main cause of nerve injuries during laparoscopy?

    <p>Direct pressure on peripheral nerves</p> Signup and view all the answers

    Which statement correctly describes a risk associated with the lithotomy position for patients with specific conditions?

    <p>It can exacerbate gastroesophageal reflux in susceptible patients.</p> Signup and view all the answers

    What effect does the lithotomy position have on the functional residual capacity (FRC) when combined with Trendelenburg?

    <p>FRC is decreased</p> Signup and view all the answers

    Which patient profile may struggle the most with hypertension when placed in the lithotomy position?

    <p>Patients with acute cardiovascular conditions</p> Signup and view all the answers

    What is the most commonly reported peripheral nerve injury related to positioning during surgeries?

    <p>Brachial plexus injury</p> Signup and view all the answers

    How does the use of 'boot-type' stirrups impact the risk of femoral nerve injury?

    <p>It decreases the risk by providing better leg support</p> Signup and view all the answers

    At what intra-abdominal pressure (IAP) does cardiac output begin to decrease?

    <p>Above 15 mm Hg</p> Signup and view all the answers

    What is the consequence of excessive abduction and external rotation of the hip during surgery?

    <p>Injury to the sciatic nerve</p> Signup and view all the answers

    What type of sensory deficits result from femoral nerve injury?

    <p>Loss of sensation over the anterior thigh and medial lower leg</p> Signup and view all the answers

    Which physiological change is commonly associated with the creation of a pneumoperitoneum?

    <p>Increase in mean arterial pressure</p> Signup and view all the answers

    Which nerve is primarily affected by prolonged hip flexion during lithotomy positioning?

    <p>Femoral nerve</p> Signup and view all the answers

    What contributes to bradyarrhythmias during laparoscopic procedures?

    <p>Vagal stimulation due to peritoneal stretch</p> Signup and view all the answers

    What is the primary function of the lateral femoral cutaneous nerve?

    <p>Sensory only to the proximal-lateral thigh</p> Signup and view all the answers

    Why are slender patients with a BMI of less than 20 kg/m considered at risk for nerve injuries?

    <p>Due to lack of subcutaneous tissue padding</p> Signup and view all the answers

    Which type of nerve injury is least likely to result in loss of motor function?

    <p>Lateral femoral cutaneous nerve injury</p> Signup and view all the answers

    What kind of abnormality may occur due to common peroneal nerve injury?

    <p>Foot drop</p> Signup and view all the answers

    Which condition may lead to hypotension during laparoscopic surgery?

    <p>Decreased cardiac output from excessive IAP</p> Signup and view all the answers

    What type of sensory deficits can result from obturator nerve injury?

    <p>Loss of sensation in the medial aspect of the thigh</p> Signup and view all the answers

    Which physiological change is NOT typically associated with pneumoperitoneum?

    <p>Increase in cardiac output</p> Signup and view all the answers

    What should be the immediate action if extraperitoneal insufflation is suspected?

    <p>Notify the surgeon and exsufflation.</p> Signup and view all the answers

    In the case of CO2 gas embolism, what is the primary consequence of the gas entering the venous system?

    <p>Creation of an air lock disrupting blood flow.</p> Signup and view all the answers

    Which of the following indicates a pneumothorax rather than other respiratory complications?

    <p>Absence of breath sounds over the affected lung.</p> Signup and view all the answers

    What is a crucial element in treating a carbon dioxide gas embolism?

    <p>Discontinuing anesthetic agents.</p> Signup and view all the answers

    Which symptom is NOT typically associated with a pneumothorax?

    <p>Severe abdominal pain.</p> Signup and view all the answers

    What complication may arise from the presence of subcutaneous emphysema during ventilation?

    <p>Inability to achieve adequate ventilation.</p> Signup and view all the answers

    Which positioning strategy is most effective for managing venous air embolism?

    <p>Left lateral position with head down.</p> Signup and view all the answers

    What is the definitive treatment for a pneumothorax that leads to physiological compromise?

    <p>Immediate thoracentesis.</p> Signup and view all the answers

    What is the primary respiratory change that occurs during laparoscopic surgery due to increased intra-abdominal pressure (IAP)?

    <p>Decreased functional residual capacity (FRC)</p> Signup and view all the answers

    What is a significant disadvantage associated with CO2 usage for the creation of pneumoperitoneum?

    <p>Increased risk of hypercarbia and respiratory acidosis</p> Signup and view all the answers

    Which respiratory complication may arise due to the cephalad displacement of the diaphragm during pneumoperitoneum?

    <p>Atelectasis and endobronchial intubation</p> Signup and view all the answers

    How does pneumoperitoneum typically affect peak airway pressures during laparoscopic surgery?

    <p>Increases due to reduced lung volume and compliance</p> Signup and view all the answers

    What is a potential result of preferential ventilation of nondependent lung portions during laparoscopic surgery?

    <p>Decreased arterial oxygen saturation</p> Signup and view all the answers

    What type of irritation is theorized to occur due to CO2 usage during pneumoperitoneum, and what is its potential consequence?

    <p>Diaphragmatic irritation causing increased postoperative pain</p> Signup and view all the answers

    What physiological effect does an elevated intra-abdominal pressure have on the diaphragm during pneumoperitoneum?

    <p>It decreases diaphragmatic excursion</p> Signup and view all the answers

    Which of the following gases poses a higher risk than CO2 for creating a pneumoperitoneum?

    <p>Helium due to low solubility in blood</p> Signup and view all the answers

    What is a primary reason for administering dexamethasone early in the perioperative phase?

    <p>It has a long half-life, extending the effects.</p> Signup and view all the answers

    Which of the following describes the mechanism of pain following laparoscopic surgery?

    <p>It results from pneumoperitoneum distension and irritation of the phrenic nerve.</p> Signup and view all the answers

    What is a common side effect associated with butyrophenones like haloperidol?

    <p>Neuroleptic malignant syndrome.</p> Signup and view all the answers

    How does carbon dioxide used during laparoscopic surgery contribute to postoperative shoulder pain?

    <p>By lowering the pH and irritating the phrenic nerve.</p> Signup and view all the answers

    What aspect of hydroxytryptamine type 3 receptor antagonists (SHT3) is true regarding their administration?

    <p>They are best administered towards the end of the surgery.</p> Signup and view all the answers

    What is a potential consequence of not monitoring ECG after droperidol administration?

    <p>Undetected arrhythmias that could be life-threatening.</p> Signup and view all the answers

    In what circumstance is dolasetron's timing not significant for preventing PONV?

    <p>When administered at the end of surgery.</p> Signup and view all the answers

    Which of the following describes a key characteristic of butyrophenones like droperidol?

    <p>They should be administered in the lowest effective dose.</p> Signup and view all the answers

    Which drug is contraindicated in patients with intestinal obstruction?

    <p>Metoclopramide</p> Signup and view all the answers

    What significant risk is associated with the use of droperidol in antiemetic therapy?

    <p>QTc prolongation</p> Signup and view all the answers

    Which of the following is a characteristic of metoclopramide?

    <p>It can cause dystonia upon rapid IV administration.</p> Signup and view all the answers

    What is the primary mechanism by which benzamide drugs like metoclopramide function?

    <p>Blocking dopamine receptors</p> Signup and view all the answers

    Which antiemetic class includes drugs that act specifically as dopamine receptor antagonists in the chemoreceptor trigger zone?

    <p>Butyrophenones</p> Signup and view all the answers

    Which of the following conditions may require monitoring the QTc interval prior to droperidol administration?

    <p>Bradycardia</p> Signup and view all the answers

    What is one of the significant complications associated with droperidol use?

    <p>Extrapyramidal reactions</p> Signup and view all the answers

    Which of these is NOT typically used to prevent postoperative nausea and vomiting (PONV)?

    <p>Fentanyl</p> Signup and view all the answers

    Study Notes

    Emotional Aspects of Gynecologic Procedures

    • Patients may experience fear, shame, anxiety, guilt, and embarrassment related to gynecologic surgeries.

    Postoperative Considerations

    • High risk of postoperative nausea and vomiting (PONV) following hysterectomy.
    • Nerve injuries may result from positioning during both open and laparoscopic hysterectomies.

    Physiological Changes and Complications

    • Creation of pneumoperitoneum with carbon dioxide (CO2) can lead to decreased respiratory compliance, increased airway pressure, and impaired cardiac function.
    • Possible laparoscopic complications include venous gas embolism (VGE), endobronchial intubation, extraperitoneal insufflation, and pneumothorax.

    Uterine Leiomyomas (Fibroids)

    • Most common benign tumors in women; growth may be rapid, especially in perimenopausal women.
    • Can cause symptoms such as menorrhagia, pelvic pain, abdominal pressure, and complications like uterine enlargement and ureteral obstruction.
    • Fibroids can occur in submucosal, intramural, or subserosal locations.
    • Potential contributors to fibroid growth include genetics and hormonal influences (estrogen and progesterone).
    • Bilateral salpingooophorectomy (BSO) is often performed in women over 45 during hysterectomy to reduce ovarian cancer risk.

    Surgical Approaches to Hysterectomy

    • Two main approaches: vaginal and abdominal, with variations based on disease, anatomy, and surgeon preference.

    Vaginal Hysterectomy

    • Conducted with the patient in dorsal lithotomy position and steep head-down tilt (Trendelenburg).
    • Advantages include better visibility, fewer complications, faster recovery, and decreased morbidity and mortality.
    • Limitations include uterine size, pelvic adhesions, and presence of gynecologic cancers requiring an abdominal approach.

    Laparoscopic-Assisted Vaginal Hysterectomy (LAVH)

    • Combines laparoscopic technique for initial surgery with vaginal approach for the remainder of the procedure.

    Abdominal Hysterectomy

    • Performed with the patient in supine position; approach determined by uterine size and need for lymph node dissection.
    • Techniques include Pfannenstiel or low midline incisions.

    Types of Abdominal Hysterectomy

    • Subtotal (Supracervical): Removal of part or all of the uterine fundus while preserving the cervix.
    • Total Hysterectomy: Removal of uterus and cervix, preserving fallopian tubes and ovaries; preferred to mitigate future cervical cancer risk.
    • Radical Hysterectomy: Performed when cancer is present, removing uterus, upper vagina, and surrounding tissues to the pelvic wall.

    Psychological Considerations for Hysterectomy Patients

    • Patients may experience fear, anxiety, embarrassment, shame, and guilt related to gynecologic surgery.
    • Chronic pain sufferers may worry about postoperative pain management.
    • Urinary incontinence may cause embarrassment; pelvic mass can induce anxiety over disfigurement and loss of sexual function.
    • Factors influencing patient feelings include religion, ethnicity, family dynamics, educational level, gender identity, and views on reproductive ability.
    • Acknowledging and managing psychological ramifications is crucial for patient care.

    Anesthetic Techniques for Hysterectomy

    • General anesthesia is the most common approach for hysterectomies.
    • Regional anesthesia provides benefits like rapid recovery, reduced postoperative nausea and vomiting (PONV), effective pain management, shorter hospital stay, and cost-efficiency.
    • Limitations of regional techniques can arise from surgical requirements and preferences of the patient or surgeon.
    • Spinal, epidural, or combined spinal-epidural anesthesia is suitable for simple hysterectomies via Pfannenstiel incision or vaginal approach.
    • Younger patients may find spinal anesthesia less desirable due to a higher risk of post dural puncture headache (PDPH).
    • Use of a pencil-point needle can decrease PDPH incidence.
    • Adequate anesthesia for uterine procedures requires a blockade at the T4-6 sensory dermatome level.

    General Anesthesia in Laparoscopic Hysterectomy

    • General anesthesia with neuromuscular blockade is standard for laparoscopic hysterectomy.
    • Airway protection is maintained through endotracheal intubation.
    • Neuromuscular blockade facilitates optimal abdominal insufflation during pneumoperitoneum, lowering intraabdominal pressures and improving surgical access and visualization.

    Disadvantages of Nitrous Oxide in Laparoscopic Hysterectomy

    • The use of nitrous oxide (N2O) is controversial in laparoscopic settings.
    • Concerns include potential bowel distension affecting surgical visibility and access, along with an increased risk of PONV.
    • Limited scientific evidence definitively supports these concerns regarding nitrous oxide.
    • Decisions about the inclusion of N2O in general anesthesia should be made by the anesthesia provider, considering individual circumstances.

    Intraoperative Physiologic Changes in Lithotomy Position

    • The lithotomy position involves elevating the legs, often combined with Trendelenburg, to enhance surgical visibility and access during hysterectomy.
    • Elevating the legs increases venous return, consequently raising mean arterial blood pressure (MAP), central venous pressure (CVP), and pulmonary artery pressure (PAP).
    • Patients with normal cardiovascular function can typically adapt to transient increases in filling pressures; those with cardiovascular disease may struggle.
    • Peripheral vascular insufficiency in patients can lead to venous stasis and ischemia in the lithotomy position.
    • Patients with hiatal hernia, gastroesophageal reflux disease (GERD), or obesity may experience decreased lower esophageal sphincter tone, raising regurgitation and aspiration risks.
    • Acute hypovolemia may not be detected due to increased venous return during the lithotomy position.
    • Transitioning the legs to the supine position redistributes blood volume, potentially causing severe hypotension.
    • While pulmonary effects are minimal in lithotomy, adding Trendelenburg can reduce functional residual capacity (FRC).
    • Obese patients and those under general anesthesia may face ventilation-perfusion (V/Q) mismatching and atelectasis, leading to compromised lung aeration.

    Risk Factors for Nerve Injury During Laparoscopic Hysterectomy

    • Nerve injuries often arise from direct pressure on peripheral nerves during surgery, particularly in the lithotomy position.
    • Length of the surgery, type of leg support, and preexisting diseases (like diabetes) influence risk from nerve pressure or stretching.
    • The "candy cane" stirrup provides limited hip and leg positioning control and is linked to a higher incidence of lower extremity nerve injuries, especially to the common peroneal nerve.
    • Use of "boot-type" stirrups that support the entire posterior leg is currently preferred to reduce injury risk.
    • Patients with a body mass index (BMI) less than 20 kg/m² may face increased risks due to insufficient subcutaneous tissue.

    Types of Nerve Injuries Associated with Hysterectomy

    • Brachial plexus injuries are common due to positioning, particularly with arms outstretched or steep Trendelenburg; these injuries lead to sensory deficits in the arm and hand.
    • Femoral nerve injury is prevalent post-gynecologic surgery, typically from retraction pressure on the nerve during open procedures or prolonged hip flexion during laparoscopy, resulting in anterior thigh sensation loss and quadriceps weakness.
    • Lateral femoral cutaneous nerve injury leads to numbness or pain in the proximal-lateral thigh; it solely carries sensory function.
    • Obturator nerve injury, stemming from prolonged hip flexion, may cause sensory loss in the medial thigh and, in rare cases, weakness of the adductor muscles.
    • Sciatic nerve injury can result from excessive hip abduction or knee flexion, causing calf sensation loss and possible foot drop owing to weakness in related muscles.
    • Common peroneal nerve injury can occur from direct pressure or overstretching; this injury presents with sensory loss in the lower leg and can lead to serious functional issues like foot drop.

    Cardiovascular Effects Associated with Pneumoperitoneum

    • Abdominal insufflation (pneumoperitoneum) affects mean arterial pressure (MAP) and heart rate (HR), with changes dependent on intraperitoneal pressure (IAP), cardiac output absorption, and ventilation mode.
    • At IAP levels below 15 mm Hg, cardiac output increases due to enhanced venous return and filling pressures.
    • IAP above 15 mm Hg decreases venous return, potentially leading to a drop in cardiac output and hypotension.
    • Pneumoperitoneum is associated with increases in systemic vascular resistance (SVR), MAP, CVP, and mean pulmonary artery pressure (PAP).
    • Vagal stimulation can cause bradyarrhythmias like bradycardia or asystole during pneumoperitoneum due to the celiac reflex or abdominal traction.
    • Tachyarrhythmias may arise from increased carbon dioxide concentrations or catecholamine release during procedures.

    Respiratory Effects of Pneumoperitoneum

    • Pneumoperitoneum during laparoscopic surgery leads to reduced lung volume and increased peak airway pressures.
    • Increased intra-abdominal pressure (IAP) decreases pulmonary compliance and diaphragmatic excursion.
    • The diaphragm shifts upward, causing early closure of smaller airways, resulting in atelectasis and decreased Functional Residual Capacity (FRC).
    • This upward shift preferentially ventilates nondependent lung areas, leading to ventilation/perfusion (V/Q) mismatch and increased intrapulmonary shunting.

    Use of CO2 in Pneumoperitoneum

    • Carbon dioxide (CO2) is favored for creating pneumoperitoneum due to its nonflammability, rapid absorption, and easy excretion via the respiratory system.
    • CO2 is readily available and cost-effective compared to other gases.
    • Disadvantages of CO2 include a higher risk of hypercarbia, potentially causing respiratory acidosis.
    • CO2 can irritate the peritoneum and diaphragm, contributing to postoperative shoulder pain.
    • Alternatives such as air, oxygen, nitrogen, argon, and helium have been studied; however, they present greater risks due to their flammability or low solubility.

    Respiratory Complications of Pneumoperitoneum

    • Endobronchial Intubation

      • Cephalad diaphragm and carina displacement can result in endobronchial intubation during pneumoperitoneum.
      • May cause decreased oxygen saturation, increased peak airway pressure, and bronchospasm.
      • Treatment involves manual ventilation with 100% oxygen and repositioning the endotracheal tube (ETT).
    • Extraperitoneal Insufflation

      • Diagnosed by a dramatic increase in end-tidal carbon dioxide (ETCO2) and subcutaneous emphysema.
      • Requires immediate surgical notification and exsufflation to eliminate CO2.
      • Typically resolves quickly after surgery, but careful assessment is needed for neck subcutaneous emphysema.
    • CO2 Gas Embolism

      • This rare but serious complication may lead to death due to CO2 entering the venous system.
      • Can occur with trocar placement into a vein or organ, creating an "air lock" in blood flow.
      • Symptoms include sudden loss of ETCO2, tachycardia, arrhythmias, hypotension, hypoxia, and cardiovascular collapse.
      • Treatment includes exsufflation, ventilation with 100% oxygen, hydration, vasopressors, aspiration from a central venous pressure (CVP) line, and positioning the patient in a head-down left lateral position.
    • Pneumothorax

      • Possible due to trauma to the diaphragm or pleura, or defects in the aortic or esophageal hiatus.
      • Symptoms may include increased airway pressure, absence of breath sounds, rapid oxygen desaturation, and hemodynamic instability.
      • Definitive treatment for a physiologically compromising pneumothorax is immediate thoracentesis.

    Postoperative Nausea and Vomiting (PONV)

    • Pharmacologic interventions for PONV include traditional antiemetic drugs:

      • Anticholinergics: Atropine, scopolamine
      • Antihistamines: Cyclizine, diphenhydramine
      • Steroids: Dexamethasone
      • Phenothiazines: Promethazine, prochlorperazine
    • Other antiemetics:

      • Metoclopramide:

        • Centrally blocks dopamine receptors in the vomiting center and chemoreceptor trigger zone (CTZ)
        • Increases gastric emptying and lower esophageal sphincter tone
        • Contraindicated in intestinal obstruction and Parkinson disease
        • Rapid IV administration may cause cramping and extrapyramidal reactions
      • Butyrophenones (Droperidol, Haloperidol):

        • Dopamine receptor antagonists within the CTZ

        • Droperidol:

          • Onset: 30-60 minutes; Duration: 4-24 hours
          • FDA black box warning due to QTc prolongation risk
          • Require ECG monitoring before and after administration
        • Haloperidol:

          • Onset: 30 minutes; Duration: ~4 hours
          • Adverse effects include extra-pyramidal symptoms and neuroleptic malignant syndrome
    • Dexamethasone:

      • Synthetic steroid used prophylactically against PONV
      • Slow onset (2 hours), long half-life (46-72 hours)
      • Efficacy increases when administered early, ideally within 1 hour before induction
    • Hydroxytryptamine type 3 receptor antagonists (5-HT3):

      • Ondansetron, dolasetron, granisetron commonly used for PONV
      • Ondansetron has a half-life of 3-4 hours; best given towards surgery completion
      • Side effects include headache, abdominal pain, and possible QT prolongation

    Shoulder Pain After Laparoscopic Surgery

    • Commonly experienced on the first postoperative day

    • Caused primarily by pneumoperitoneum, resulting in:

      • Distension of the peritoneum and abdominal wall
      • Traction on nerves and potential blood vessel injury
    • Carbon dioxide used in pneumoperitoneum decreases intraperitoneal pH, leading to acidosis

    • Inflammation irritates the phrenic nerve, perceived as shoulder pain

    • Ketorolac (Toradol) is an effective treatment for managing shoulder pain post-surgery

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    Description

    Explore the key points surrounding open and laparoscopic hysterectomies. This quiz covers the psychological impacts on patients, risks of postoperative nausea and vomiting, and potential nerve injuries associated with these surgical procedures. Test your knowledge of these gynecologic approaches and their implications.

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