L3 (T1): Introduction to the Hypothalamic-Pituitary Axis: Hormones, Assessment of function
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Questions and Answers

How many loops form the hypothalamic-pituitary axis?

  • 4 loops
  • 1 loop
  • 3 loops
  • 2 loops (correct)

    • What is the function of the anterior lobe of the pituitary gland?

  • Assessment of the hypothalamic-pituitary axis
  • Feedback loops associated with each hormone
  • Production of hormones (correct)
  • Blood supply and nervous innervation

    • Which blood vessels supply the hypothalamus and the pituitary gland?

  • Sinusoidal capillaries
  • Superior and inferior hypophysial arteries (correct)
  • Internal carotid artery
  • Long portal veins

    • Where does the blood from the primary plexus drain into?

    <p>Long portal veins</p> Signup and view all the answers

    What is the connection between the two plexuses of capillaries called?

    <p>Portal system</p> Signup and view all the answers

    Which part of the pituitary gland secretes releasing hormones?

    <p>Arcuate nucleus</p> Signup and view all the answers

    What is the target tissue for Growth Hormone (GH)?

    <p>Bone &amp; Muscle</p> Signup and view all the answers

    What hormone stimulates the adrenal glands to release cortisol?

    <p>Adrenocorticotrophic hormone (ACTH)</p> Signup and view all the answers

    Which hormone is responsible for the production of milk in the breast?

    <p>prolactin</p> Signup and view all the answers

    What is the primary function of prolactin?

    <p>Production of milk</p> Signup and view all the answers

    Which hormone is secreted by the posterior pituitary gland and triggers muscular contractions during childbirth?

    <p>oxytocin</p> Signup and view all the answers

    What is the role of antidiuretic hormone (ADH) in the kidneys?

    <p>Impairs the kidney's filtering of bodily fluids</p> Signup and view all the answers

    Which hormone promotes the secretion of insulin-like growth factor 1 (IGF-1)?

    <p>Growth hormone</p> Signup and view all the answers

    Which part of the brain secretes oxytocin and antidiuretic hormone (ADH)?

    <p>Hypothalamus</p> Signup and view all the answers

    Which hormone is responsible for the condition known as acromegaly?

    <p>Growth hormone</p> Signup and view all the answers

    Which hormone is hypersecreted in Cushing's syndrome?

    <p>Adrenocorticotrophic hormone</p> Signup and view all the answers

    What is the primary treatment for acromegaly?

    <p>Surgical removal</p> Signup and view all the answers

    What condition is caused by the hypersecretion of Growth Hormone during childhood?

    <p>Gigantism</p> Signup and view all the answers

    What is the visual defect known as bitemporal hemianopia associated with?

    <p>Pituitary tumors</p> Signup and view all the answers

    What test is used to assess the integrity of the hypothalamic-pituitary-adrenal axis?

    <p>Insulin tolerance testing</p> Signup and view all the answers

    Which region of the brain is located below the corpus callosum?

    <p>Hypothalamus</p> Signup and view all the answers

    What connects the hypothalamus to the pituitary gland?

    <p>Pituitary stalk (infundibulum)</p> Signup and view all the answers

    Which part of the pituitary gland receives direct innervation from the terminals of the paraventricular and supraoptic nuclei?

    <p>Posterior Pituitary (neurohypophysis)</p> Signup and view all the answers

    Which arteries supply blood to the Hypothalamic-Pituitary Axis?

    <p>Superior and inferior hypophysial arteries</p> Signup and view all the answers

    Which plexus of capillaries facilitates the easier movement of large molecules in the Hypothalamic-Pituitary Axis?

    <p>Sinusoidal capillaries</p> Signup and view all the answers

    Which part of the Hypothalamic-Pituitary Axis doesn't receive direct innervation?

    <p>Anterior Pituitary (adenohypophysis)</p> Signup and view all the answers

    Which part of the brain is the hypothalamus located in?

    <p>Cerebrum</p> Signup and view all the answers

    What is the primary function of the hypothalamic-pituitary axis?

    <p>To maintain homeostasis</p> Signup and view all the answers

    Which gland is divided into two lobes, the posterior and anterior lobes?

    <p>Pituitary gland</p> Signup and view all the answers

    What is the role of the posterior pituitary gland?

    <p>Control of water balance</p> Signup and view all the answers

    Which hormone is responsible for the production of milk in the breast?

    <p>Prolactin</p> Signup and view all the answers

    What hormone stimulates the adrenal glands to release cortisol?

    <p>Adrenal cortical traffic common</p> Signup and view all the answers

    What is the primary function of prolactin?

    <p>Milk production in the breast</p> Signup and view all the answers

    What hormone promotes the secretion of insulin-like growth factor 1 (IGF-1)?

    <p>Growth hormone</p> Signup and view all the answers

    Which structure is located just below the corpus callosum?

    <p>Hypothalamus</p> Signup and view all the answers

    What is the function of the hypothalamus?

    <p>All of the above</p> Signup and view all the answers

    What is the purpose of the sinusoidal nature of the capillary beds in the hypothalamic-pituitary axis?

    <p>To allow for easier movement of larger molecules</p> Signup and view all the answers

    Where does the majority of the blood supply to the pituitary gland come from?

    <p>Carotid artery</p> Signup and view all the answers

    Which hormone is secreted in response to growth hormone releasing hormone through releasing hormone right at the start?

    <p>Human growth hormone</p> Signup and view all the answers

    Which hormone is responsible for increasing the amount of energy obtained from glucose in the liver?

    <p>Human growth hormone</p> Signup and view all the answers

    What condition can occur if the regulatory pathway for growth hormone is perturbed?

    <p>Acromegaly</p> Signup and view all the answers

    Which hormone is produced in response to corticotropin-releasing hormone and eventually leads to the production of cortisol?

    <p>Adrenal traffic hormone</p> Signup and view all the answers

    Which type of capillaries are found in the pituitary gland?

    <p>Sinusoidal capillaries</p> Signup and view all the answers

    Where is the pituitary gland located in the brain?

    <p>Below the hypothalamus</p> Signup and view all the answers

    Which nuclei are responsible for projecting nerve terminals into the posterior lobe of the pituitary gland?

    <p>Ventricular and super optic nuclei</p> Signup and view all the answers

    Where are hormones secreted from in the pituitary gland?

    <p>Cell types in the anterior lobe</p> Signup and view all the answers

    Which hormone is responsible for the production of testosterone in biological males?

    <p>Luteinizing hormone (LH)</p> Signup and view all the answers

    What is the primary function of thyroid stimulating hormone (TSH)?

    <p>Increases metabolic rate</p> Signup and view all the answers

    Which hormone is responsible for the condition known as hypothyroidism?

    <p>Thyroid stimulating hormone (TSH)</p> Signup and view all the answers

    What is the effect of cortisol on the immune system?

    <p>Suppresses immune response</p> Signup and view all the answers

    Which part of the brain is NOT involved in the hypothalamic-pituitary axis?

    <p>Inferior boom</p> Signup and view all the answers

    What is the main function of the hypothalamic-pituitary axis?

    <p>To control hormone secretion</p> Signup and view all the answers

    What is the relationship between the hypothalamus and the pituitary gland?

    <p>They form the hypothalamic-pituitary axis</p> Signup and view all the answers

    What is the role of the anterior lobe of the pituitary gland?

    <p>To control hormone secretion</p> Signup and view all the answers

    What is the function of antidiuretic hormone (ADH) in the kidneys?

    <p>To decrease urine production</p> Signup and view all the answers

    What is the primary treatment for acromegaly?

    <p>Surgery</p> Signup and view all the answers

    Study Notes

    Hypothalamic-Pituitary Axis

    • The hypothalamic-pituitary axis is composed of two loops: the short portal vessel loop and the long portal vessel loop
    • The anterior lobe of the pituitary gland produces and secretes hormones that regulate various bodily functions

    Blood Supply

    • The hypothalamus and pituitary gland are supplied by the superior and interior hypophysial arteries
    • The primary plexus of capillaries drains into the portal veins, which then drain into the anterior lobe of the pituitary gland

    Hypothalamus and Pituitary Gland Connection

    • The hypothalamus and pituitary gland are connected by the pituitary stalk
    • The hypothalamus secretes releasing hormones that stimulate the anterior lobe of the pituitary gland to produce and secrete hormones

    Hormones and Functions

    • Growth Hormone (GH) targets the liver, stimulating the production of insulin-like growth factor 1 (IGF-1)
    • Adrenocorticotropic Hormone (ACTH) stimulates the adrenal glands to release cortisol
    • Prolactin is responsible for the production of milk in the breast and has a secondary function in osmoregulation
    • Oxytocin triggers muscular contractions during childbirth
    • Antidiuretic Hormone (ADH) regulates water reabsorption in the kidneys
    • Thyroid-Stimulating Hormone (TSH) regulates the production of thyroid hormones

    Pituitary Gland

    • The pituitary gland is divided into two lobes: the anterior lobe, which produces and secretes hormones, and the posterior lobe, which stores and releases hormones
    • The posterior lobe of the pituitary gland secretes oxytocin and antidiuretic hormone (ADH)
    • The anterior lobe of the pituitary gland receives direct innervation from the terminals of the paraventricular and supraoptic nuclei

    Hypothalamus

    • The hypothalamus is located in the diencephalon region of the brain
    • The primary function of the hypothalamus is to regulate body temperature, hunger, thirst, and other basic bodily functions

    Other

    • Acromegaly is caused by the hypersecretion of Growth Hormone in adults
    • Hypersecretion of Growth Hormone during childhood can cause gigantism
    • Bitemporal hemianopia is a visual defect associated with pituitary gland tumors
    • The metyrapone test is used to assess the integrity of the hypothalamic-pituitary-adrenal axis

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    Related Documents

    Introduction to the Hypothalamic-Pituitary Axis - Student Copy(1).pptx

    Description

    Test your knowledge on the anatomy and function of the hypothalamus and its associated structures. Learn about the anterior and posterior lobes, as well as the important role of the infundibulum. Explore topics such as blood supply, plexuses, and sinusoidal capillaries.

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