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Hypoglycemia in Children

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Questions and Answers

At what plasma glucose concentration does functional brain failure occur?

Lower than 54 mg/dL (correct)

At 100 mg/dL

Above 100 mg/dL

Below 70 mg/dL

What is the mean glucose production rate in children from premature infants to 6 years old?

10-12 mg/kg/min

2-4 mg/kg/min

15-18 mg/kg/min

5-8 mg/kg/min (correct)

Which enzyme is involved in the breakdown of glycogen into glucose?

Amylo-1,6-glucosidase (correct)

Phosphofructokinase

Phosphoglucomutase

Glucokinase

What happens to plasma glucose concentrations during a fast?

They decline toward hypoglycemic values Signup and view all the answers

What is the approximate mean glucose production rate in adults?

2.3 mg/kg/min Signup and view all the answers

What is the fate of the brain in prolonged and profound hypoglycemia?

It suffers permanent injury and eventually death Signup and view all the answers

What is the primary fuel source for the body during prolonged fasting?

Free fatty acids Signup and view all the answers

Which of the following hormones stimulates glycogen synthesis?

Cortisol Signup and view all the answers

What is the approximate duration of fasting before plasma glucose decreases below 70 mg/dL in most full-term infants?

15 hours Signup and view all the answers

During fasting, what is the source of glucose for the brain and other tissues?

Gluconeogenesis in the liver Signup and view all the answers

What is the byproduct of mitochondrial fatty acid oxidation in the liver during prolonged fasting?

Ketone bodies Signup and view all the answers

What is the response to decreasing plasma glucose concentrations in adults?

Decreased insulin secretion Signup and view all the answers