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Questions and Answers
What is the defining characteristic of a hypertrophic scar?
What is the defining characteristic of a hypertrophic scar?
- Excessive angiogenesis with low blood flow
- Overgrowth of dermal constituents beyond the boundaries of the original wound (correct)
- High rates of expansion
- Reduced collagen deposition
What is the primary cause of hypertrophic scarring?
What is the primary cause of hypertrophic scarring?
- Decreased fibroblast activity
- Prolonged inflammatory process (correct)
- Reduced inflammatory mediators
- Excessive collagen degradation
What characterizes the collagen fiber alignment in a hypertrophic scar?
What characterizes the collagen fiber alignment in a hypertrophic scar?
- Collagen alignment in straight patterns
- Collagen alignment in whorls (correct)
- Decrease in chondroitin sulfate A
- Small bundles of collagen fiber in reticular dermis
When does hypertrophic scar (HTS) typically begin to appear post wound healing?
When does hypertrophic scar (HTS) typically begin to appear post wound healing?
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What is the average time for scar maturation in hypertrophic scarring?
What is the average time for scar maturation in hypertrophic scarring?
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Study Notes
Hypertrophic Scarring Characteristics
- The defining characteristic of a hypertrophic scar is excessive collagen production and deposition, leading to a raised, thick, and red scar.
Causes of Hypertrophic Scarring
- The primary cause of hypertrophic scarring is prolonged inflammation during the wound healing process.
Collagen Fiber Alignment
- In a hypertrophic scar, collagen fiber alignment is characterized by a whorl-like or irregular pattern, differing from the usual linear pattern found in normal scars.
Onset of Hypertrophic Scarring
- Hypertrophic scars typically begin to appear 3-6 weeks post-wound healing and may take several months to a year or more to mature.
Scar Maturation Time
- The average time for scar maturation in hypertrophic scarring is around 12-18 months, although this process can take up to 2 years or more in some cases.
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Description
Test your knowledge about hypertrophic scars, which are an overgrowth of dermal constituents within the boundaries of a wound. Learn about the imbalance of matrix degradation and collagen biosynthesis that leads to excess collagen accumulation in the wound.
