Hyperthyroidism: Signs, Symptoms, and Etiology

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18 Questions

What is the medical term used to describe the signs and symptoms associated with an overproduction of thyroid hormone?

Thyrotoxicosis

Which hormone is responsible for the increased metabolic rate in hyperthyroidism?

T3

What is the etiology of hyperthyroidism?

Autoimmune disorder.

Which clinical manifestation is associated with ophthalmopathy in hyperthyroidism?

Protrusion of the eyeball.

What is the primary pharmacologic therapy for diabetes insipidus (DI) mentioned in the text?

Desmopressin (DDAVP)

In mild forms of DI, which medication is used because it potentiates the action of vasopressin?

Thiazide diuretics

Which type of medication is used to treat the nephrogenic form of DI according to the text?

Prostaglandin inhibitors (ibuprofen, indomethacin, aspirin)

What should the nurse educate the patient, family, and other caregivers about, as part of nursing management for DI?

Follow-up care, prevention of complications, and emergency measures

What is a major complication of hypothyroidism?

Myxedema coma

Which condition is characterized by deficient production of vasopressin?

Diabetes insipidus

What are the clinical manifestations of Acromegaly?

Enlarged jaw, thickened tongue, enlarged and weakened hands, oily and leathery skin, and disturbance in sleep

What is the main cause of hyperpituitarism?

Benign tumor of the pituitary gland

What is the characteristic age of onset for Acromegaly?

Between the ages of 30-50 with slow development

What is the treatment for hyperpituitarism?

Surgery, medication to inhibit GH synthesis, and a salt-restricted diet

Which condition is marked by deficient secretion of the anterior pituitary hormones?

Hypopituitarism

What is a symptom of hypothyroidism?

Cold intolerance

What is a cause of diabetes insipidus?

Surgical treatment of a brain tumor

What is the management for hypothyroidism?

Monitoring vital signs, low-calorie high-fiber diet, warm environment during cold weather, pharmacological treatment with T3, T4 or thyroglobulin

Study Notes

  • Wearing dark glasses under the sun helps protect the eyes from sunlight.
  • Hypothyroidism is a condition where the thyroid gland does not produce sufficient thyroid hormones.
  • Causes of hypothyroidism include autoimmune disease, surgery, radiation therapy, antithyroid drugs, and thyroiditis.
  • Decreased metabolic rate, decreased body heat production, and hypercalcemia are three concepts related to hypothyroidism.
  • Clinical manifestations of hypothyroidism include obesity, anorexia, bradycardia, cold intolerance, constipation, slowness in physical and mental reaction, brittle nails, and irregular menstruation.
  • Management of hypothyroidism includes monitoring vital signs, a low-calorie, high-fiber diet, providing a warm environment during cold weather, and pharmacological treatment with T3, T4, or thyroglobulin.
  • Myxedema coma is a severe complication of hypothyroidism characterized by hypothermia, unconsciousness, and the need for intravenous thyroid hormone, correction of hypothermia, maintenance of vital functions, and treatment of the underlying cause.
  • Hyperpituitarism is a condition of excessive growth hormone production, also known as Acromegaly and Gigantism.
  • Acromegaly occurs after epiphyseal closure and causes thickening and transverse growth, with onset typically between the ages of 30-50 and a slow development.
  • Gigantism occurs before epiphyseal closure and affects infants and children, with abrupt development.
  • Clinical manifestations of Acromegaly include an enlarged jaw, thickened tongue, enlarged and weakened hands, oily and leathery skin, and disturbance in sleep.
  • Clinical manifestations of Gigantism include muscular hypertonia, exophthalmos, a highly arched palate, and disturbance in sleep.
  • Causes of hyperpituitarism include a benign tumor of the pituitary gland and 60% to 80% of pituitary tumors.
  • Treatment for hyperpituitarism includes surgery, medication to inhibit GH synthesis, and a salt-restricted diet.
  • Hypopituitarism is marked by deficient secretion of the anterior pituitary hormones, leading to dwarfism, metabolic dysfunction, sexual immaturity, and growth retardation.
  • Causes of hypopituitarism include tumors, congenital defects, pituitary ischemia, partial or total hypophysectomy, and radiation therapy.
  • Diabetes insipidus is a condition of deficient production of vasopressin, leading to large volumes of dilute urine and intense thirst.
  • Causes of diabetes insipidus include surgical treatment of a brain tumor, nonsurgical brain tumors, traumatic brain injury, infections of the nervous system, post-hypophysectomy, failure of renal tubules to respond to ADH, and the use of specific medications.
  • Management of diabetes insipidus includes replacing ADH, ensuring adequate fluid replacement, and identifying and correcting the underlying intracranial pathology.

Test your knowledge of hyperthyroidism with this quiz. Explore the medical term to describe the signs and symptoms associated with an overproduction of thyroid hormone, the basic concepts of increased metabolic rate, body heat production, and hypocalcemia, and the etiology and clinical manifestations of the disorder.

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