Hyperthyroidism and Radioiodine Treatment Quiz

<p>Hypothyroidism following treatment. (B)</p> Signup and view all the answers

<p>Corticosteroids or surgical decompression. (B)</p> Signup and view all the answers

<p>Increases the basal metabolic rate (C)</p> Signup and view all the answers

<p>Thyroid-stimulating hormone (TSH) (B)</p> Signup and view all the answers

<p>They inhibit their release (A)</p> Signup and view all the answers

<p>Increased calorigenesis (B)</p> Signup and view all the answers

<p>Releases TRH to stimulate TSH release (C)</p> Signup and view all the answers

<p>Decreases physiologic and metabolic activity (C)</p> Signup and view all the answers

<p>80% (D)</p> Signup and view all the answers

<p>Hypothyroidism (C)</p> Signup and view all the answers

<p>Exophthalmos (A)</p> Signup and view all the answers

<p>Dietary iodine deficiency (B)</p> Signup and view all the answers

<p>Lithium (A)</p> Signup and view all the answers

<p>Myxedema (B)</p> Signup and view all the answers

<p>Inhibits T4 to T3 conversion (B)</p> Signup and view all the answers

<p>Weight loss (B)</p> Signup and view all the answers

<p>Thyroid enlargement and hyperthyroidism (B)</p> Signup and view all the answers

<p>Antibodies to the TSH receptor (D)</p> Signup and view all the answers

<p>Reduce iodination of tyrosyl residues in thyroglobulin (B)</p> Signup and view all the answers

<p>Rashes (B)</p> Signup and view all the answers

<p>Blocks the absorption of radioactive iodine (C)</p> Signup and view all the answers

<p>Preparation for surgical resection of the thyroid (A)</p> Signup and view all the answers

<p>Thyroid storm (C)</p> Signup and view all the answers

<p>Several weeks (C)</p> Signup and view all the answers

<p>Hypotension (D)</p> Signup and view all the answers

<p>Complete remission of Graves disease (C)</p> Signup and view all the answers

<p>β-blockers are used to manage cardiovascular symptoms temporarily. (C)</p> Signup and view all the answers

<p>Levothyroxine (D)</p> Signup and view all the answers

<p>Interactions with dietary supplements affecting its absorption. (D)</p> Signup and view all the answers

<p>Acute emergencies such as myxoedema coma (A)</p> Signup and view all the answers

<p>Cardiac dysrhythmias and potential cardiac failure (C)</p> Signup and view all the answers

<p>They are essential for antithyroid activity due to their S–C–N group. (C)</p> Signup and view all the answers

<p>On an empty stomach, either 1 hour before or 4 hours after meals (A)</p> Signup and view all the answers

<p>They provide a long-term cure for hyperthyroidism. (D)</p> Signup and view all the answers

Tri-iodothyronine (T3) is more active than thyroxine (T4). Both are synthesized within the thyroid follicle.

The hypothalamus releases TRH (thyrotropin-releasing hormone), which stimulates the pituitary gland to release TSH (thyroid-stimulating hormone).

It plays a crucial role in regulating the basal metabolic rate by influencing the metabolism of carbohydrates, fats, and proteins.

This refers to the body's ability to produce heat, often increased by thyroid hormones.

The thyroid gland releases T3 and T4 into the bloodstream. The liver and muscles then convert T4 into the more active T3.

High levels of T3 and T4 in the bloodstream suppress the release of TRH and TSH, preventing excessive thyroid hormone production.

Hypothyroidism is characterized by low T4 levels, leading to impaired growth, decreased metabolic activity, and reduced heat production.

Hyperthyroidism is characterized by high T4 levels leading to increased metabolism, rapid heartbeat, and weight loss.

Excessive thyroid hormone production, causing hyperactivity of organ systems, increased metabolic rate, and heat production.

A condition where the thyroid gland is enlarged but functions normally, often caused by iodine deficiency.

A condition where the thyroid gland is underactive, leading to slowed metabolism, fatigue, and weight gain.

A condition characterized by protruding eyeballs, often associated with hyperthyroidism.

An autoimmune disease causing hypothyroidism, where the body attacks its own thyroid gland.

A condition characterized by hyperthyroidism, goiter, and exophthalmos, caused by antibodies stimulating the thyroid gland.

A medication that can cause both hypothyroidism and hyperthyroidism, commonly inhibiting the conversion of T4 to T3.

A medication that can inhibit the release of thyroid hormones, potentially leading to hypothyroidism.

A medication that increases the synthesis of thyroid hormones.

A medication used for the treatment of hypothyroidism due to its faster onset of action and shorter duration of action.

The medication should be taken on an empty stomach to prevent the food from interfering with its absorption.

Certain medications or substances can impair levothyroxine absorption, so they should be taken at different times.

Antithyroid medications suppress thyroid hormone production, but they don't address the underlying autoimmune cause.

Carbamazepine and propylthiouracil are used in hyperthyroidism treatment.

The S–C–N group is essential for the antithyroid action of thioureylenes.

Radioactive iodine treatment is used in cases of hyperthyroidism when other treatments are not effective or when the condition recurs.

Radioactive iodine (RAI) is a common treatment for hyperthyroidism and thyroid cancer. Its beta radiation targets and destroys thyroid cells.

While effective, RAI can cause hypothyroidism later on, especially in patients with Graves' disease. This is because the treatment destroys thyroid tissue.

Beta-blockers are helpful in managing many symptoms of hyperthyroidism, such as rapid heartbeat, shaky hands, and anxiety. They are used temporarily while other treatments take effect or during preparation for surgery.

Guanethidine, an eye drop, can help reduce exophthalmos (protruding eyes) in hyperthyroidism. It works by inhibiting nerves that contribute to the condition.

In cases of severe exophthalmos, treatment may involve corticosteroids (anti-inflammatory drugs) or surgical decompression of the eye socket.

Carbimazole and propylthiouracil are medications used to treat hyperthyroidism by reducing the production of thyroid hormones. They achieve this by inhibiting the enzyme thyroid peroxidase, which is crucial for the synthesis of thyroid hormones. These medications work within the thyroid gland itself, affecting the iodination of tyrosine residues, a critical step in thyroid hormone formation.

While thioureylenes are generally safe during pregnancy, they can cross the placenta and may impact the fetal thyroid gland. Therefore, careful monitoring and consideration of potential risks are essential.

Iodine, when converted to iodide (I−), can reduce thyroid hormone release from the thyroid gland. This effect, however, is temporary, lasting only a few weeks. Iodine/iodide is administered orally in solutions containing potassium iodide.

Iodine/iodide is often used to prepare hyperthyroid patients for surgery. It helps to reduce thyroid hormone levels, making surgery safer. It can also help in managing thyroid storm, a severe form of hyperthyroidism, as it helps reduce the symptoms.

After a nuclear reactor accident, administering potassium iodide is crucial. It helps block the thyroid's uptake of radioactive iodine, which can damage thyroid tissue. This significantly lowers the risk of thyroid cancer and other radiation-related thyroid conditions.

Thyroid storm is a life-threatening condition with dangerously high thyroid hormone levels. It results in a hypermetabolic state, affecting various organs. Improved preoperative management with potassium iodide has significantly reduced instances of thyroid storm during thyroid surgery.

Thyroid hormones are naturally absorbed by the thyroid gland. However, in case of a nuclear disaster, the radioactive iodine isotope ¹³¹I can damage thyroid tissue. Potassium iodide helps prevent the thyroid from absorbing this harmful isotope, lowering the risk of thyroid cancer and other radiation-related conditions.

In cases of a nuclear reactor accident, potassium iodide is administered to protect the thyroid from absorbing harmful radioactive iodine isotopes. This strategy effectively minimizes the risk of thyroid cancer and other radiation-related thyroid problems.