Podcast
Questions and Answers
What is the primary goal of treating hypertension?
What is the primary goal of treating hypertension?
- Preventing any reduction in blood pressure that is below normal.
- Lowering blood pressure to a specific target.
- Focusing solely on reducing systolic blood pressure.
- Reducing morbidity and mortality from cardiovascular events and kidney disease. (correct)
According to the 2017 ACC/AHA guideline, what is the recommended blood pressure goal for most patients with hypertension?
According to the 2017 ACC/AHA guideline, what is the recommended blood pressure goal for most patients with hypertension?
- Less than 130/90 mm Hg.
- Less than 120/80 mm Hg.
- Less than 140/90 mm Hg.
- Less than 130/80 mm Hg. (correct)
In what population does the Kidney Disease Improving Global Outcomes (KDIGO) guidelines recommend a systolic blood pressure (SBP) goal of less than 120 mm Hg?
In what population does the Kidney Disease Improving Global Outcomes (KDIGO) guidelines recommend a systolic blood pressure (SBP) goal of less than 120 mm Hg?
- Patients with chronic kidney disease not receiving dialysis. (correct)
- Patients with diabetes.
- Patients with ASCVD
- Older ambulatory patients.
What was the main finding of the Systolic Blood Pressure Intervention Trial (SPRINT)?
What was the main finding of the Systolic Blood Pressure Intervention Trial (SPRINT)?
What is clinical inertia in the context of hypertension management?
What is clinical inertia in the context of hypertension management?
For a patient with elevated blood pressure or stage 1 hypertension at low risk of ASCVD, what is the appropriate initial treatment strategy?
For a patient with elevated blood pressure or stage 1 hypertension at low risk of ASCVD, what is the appropriate initial treatment strategy?
When should drug therapy be initiated in low-risk patients with hypertension?
When should drug therapy be initiated in low-risk patients with hypertension?
How should blood pressure control be managed in the context of compelling indications?
How should blood pressure control be managed in the context of compelling indications?
According to the guidelines, what is the first-line antihypertensive treatment option for most patients?
According to the guidelines, what is the first-line antihypertensive treatment option for most patients?
In which situation should beta-blocker therapy be reserved?
In which situation should beta-blocker therapy be reserved?
If albuminuria is present in a patient with diabetes, how should they be treated?
If albuminuria is present in a patient with diabetes, how should they be treated?
According to the information, which diuretic is a 'thiazide-like' diuretic?
According to the information, which diuretic is a 'thiazide-like' diuretic?
Why are loop diuretics not first-line agents in most patients with hypertension?
Why are loop diuretics not first-line agents in most patients with hypertension?
Which diuretics are preferred over thiazides in patients with severe kidney dysfunction?
Which diuretics are preferred over thiazides in patients with severe kidney dysfunction?
Which class of diuretics should be reserved for patients experiencing diuretic-induced hypokalemia?
Which class of diuretics should be reserved for patients experiencing diuretic-induced hypokalemia?
Abrupt discontinuation of which drug class may cause rebound hypertension?
Abrupt discontinuation of which drug class may cause rebound hypertension?
According to the information provided, nonselective beta-blockers should be avoided in patients with which co-existing condition?
According to the information provided, nonselective beta-blockers should be avoided in patients with which co-existing condition?
Which of the following is a common characteristic of mixed alpha- and beta-blockers?
Which of the following is a common characteristic of mixed alpha- and beta-blockers?
Beta-blockers with Intrinsic Sympathomimetic Activity (ISA) are contraindicated in patients with which condition?
Beta-blockers with Intrinsic Sympathomimetic Activity (ISA) are contraindicated in patients with which condition?
What was the key finding regarding doxazosin in the ALLHAT study?
What was the key finding regarding doxazosin in the ALLHAT study?
According to the ALLHAT study, which therapy was superior in preventing one or more major forms of cardiovascular disease?
According to the ALLHAT study, which therapy was superior in preventing one or more major forms of cardiovascular disease?
Which of the following is not an established benefit of ACE inhibitors?
Which of the following is not an established benefit of ACE inhibitors?
Which statement is true regarding ACE inhibitor-induced cough?
Which statement is true regarding ACE inhibitor-induced cough?
What is the primary action of Angiotensin Receptor Blockers (ARBs) in reducing blood pressure?
What is the primary action of Angiotensin Receptor Blockers (ARBs) in reducing blood pressure?
What condition is a contraindication for the use of an ACEI, ARB, or direct renin inhibitor?
What condition is a contraindication for the use of an ACEI, ARB, or direct renin inhibitor?
What should patients be monitored for within 4 weeks of starting or increasing the dose of their ACE inhibitor, to mitigate serious adverse events?
What should patients be monitored for within 4 weeks of starting or increasing the dose of their ACE inhibitor, to mitigate serious adverse events?
Amlodipine lowers blood pressure by:
Amlodipine lowers blood pressure by:
For patients with a history of gout, which class of diuretics should be used with caution?
For patients with a history of gout, which class of diuretics should be used with caution?
When is chronotherapy indicated as a treatment for hypertension?
When is chronotherapy indicated as a treatment for hypertension?
What is the American Society of Hypertension recommendation for the ideal combination therapy?
What is the American Society of Hypertension recommendation for the ideal combination therapy?
What consideration should be kept in mind about increasing antihypertensive medications?
What consideration should be kept in mind about increasing antihypertensive medications?
If a patient taking hydralazine or minoxidil begins showing compensatory baroreceptor responses, what medication should also be prescribed?
If a patient taking hydralazine or minoxidil begins showing compensatory baroreceptor responses, what medication should also be prescribed?
What is a consideration to keep in mind regarding potassium-sparing diuretics and aldosterone?
What is a consideration to keep in mind regarding potassium-sparing diuretics and aldosterone?
Flashcards
Overall Goal of Hypertension Treatment
Overall Goal of Hypertension Treatment
Reduce morbidity and mortality from CV events and kidney disease.
Goal BP for most hypertensive patients
Goal BP for most hypertensive patients
A BP of <130/80 mm Hg.
Clinical Inertia in Hypertension
Clinical Inertia in Hypertension
Office visit where no therapeutic action is taken to lower BP in a patient with uncontrolled hypertension.
DASH Diet
DASH Diet
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Preferred Initial Antihypertensive Agents
Preferred Initial Antihypertensive Agents
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Nondihydropyridine CCBs Use
Nondihydropyridine CCBs Use
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Thiazide Diuretics
Thiazide Diuretics
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Hypertension in Older People
Hypertension in Older People
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Orthostatic Hypotension
Orthostatic Hypotension
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Hypertension in Children
Hypertension in Children
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Aliskiren
Aliskiren
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Direct arterial vasodilator
Direct arterial vasodilator
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Prazosin and terazosin
Prazosin and terazosin
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ALLHAT Trial
ALLHAT Trial
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Beta Blockers and CVD
Beta Blockers and CVD
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Compelling Indications
Compelling Indications
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Amiloride and Triamterene
Amiloride and Triamterene
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Self-monitoring device
Self-monitoring device
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What is Aliskiren
What is Aliskiren
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What does Methyldopa do
What does Methyldopa do
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Clonidine, guanfacine, and methyldopa function
Clonidine, guanfacine, and methyldopa function
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Study Notes
- Reducing morbidity and mortality from cardiovascular events and kidney disease is the overall goal for treating hypertension.
- Select antihypertensive drug therapy based on evidence that demonstrates a reduction in morbidity and mortality, and not merely a reduction in blood pressure.
- A surrogate goal of therapy is achieved by treating patients with hypertension to achieve a desired goal blood pressure.
- Reducing blood pressure to a goal does not guarantee the prevention of hypertension-associated complications but it does significantly lower the risk.
- Targeting a goal blood pressure is the standard of care for how clinicians evaluate response to therapy.
- It is the primary method used to determine the need for titration and regimen modification.
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