Podcast
Questions and Answers
What is the normal blood pressure range?
What is the normal blood pressure range?
Is isolated systolic hypertension characterized by elevated diastolic pressure?
Is isolated systolic hypertension characterized by elevated diastolic pressure?
False
What type of hypertension is most common among individuals aged 25-50?
What type of hypertension is most common among individuals aged 25-50?
Primary hypertension
A blood pressure reading of 135/74 mmHg is classified as __________ hypertension.
A blood pressure reading of 135/74 mmHg is classified as __________ hypertension.
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Match the types of hypertension with their descriptions:
Match the types of hypertension with their descriptions:
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Which statement about diastolic blood pressure is true?
Which statement about diastolic blood pressure is true?
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A blood pressure reading of 148/92 mmHg indicates Stage 2 Hypertension.
A blood pressure reading of 148/92 mmHg indicates Stage 2 Hypertension.
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What is the significance of averaging two blood pressure readings?
What is the significance of averaging two blood pressure readings?
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The primary mechanism contributing to primary hypertension includes increased activity of the __________ nervous system.
The primary mechanism contributing to primary hypertension includes increased activity of the __________ nervous system.
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What condition may cause high blood pressure readings only in a clinical setting?
What condition may cause high blood pressure readings only in a clinical setting?
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Which of the following is a common risk factor for hypertension?
Which of the following is a common risk factor for hypertension?
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Renin-Angiotensin-Aldosterone System (RAAS) decreases blood pressure by reducing blood volume.
Renin-Angiotensin-Aldosterone System (RAAS) decreases blood pressure by reducing blood volume.
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Name one endocrine cause of hypertension.
Name one endocrine cause of hypertension.
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Hypertensive _____ occurs without target organ damage.
Hypertensive _____ occurs without target organ damage.
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Match the medication to its class:
Match the medication to its class:
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What is a common complication of uncontrolled hypertension?
What is a common complication of uncontrolled hypertension?
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Cushing's Syndrome is associated with elevated blood pressure due to increased sensitivity to catecholamines.
Cushing's Syndrome is associated with elevated blood pressure due to increased sensitivity to catecholamines.
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What lifestyle change can help manage hypertension?
What lifestyle change can help manage hypertension?
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Hypertensive emergencies can lead to _____ from inadequate perfusion.
Hypertensive emergencies can lead to _____ from inadequate perfusion.
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Which of the following medications can be used for managing hypertensive emergencies?
Which of the following medications can be used for managing hypertensive emergencies?
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Which blood pressure category is defined as a systolic reading of 130-139 mmHg and a diastolic reading of 80-89 mmHg?
Which blood pressure category is defined as a systolic reading of 130-139 mmHg and a diastolic reading of 80-89 mmHg?
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Isolated diastolic hypertension is characterized by elevated systolic pressure.
Isolated diastolic hypertension is characterized by elevated systolic pressure.
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What term is used for high blood pressure readings in a clinical setting but normal outside it?
What term is used for high blood pressure readings in a clinical setting but normal outside it?
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A reading of greater than __________ mmHg is indicative of hypertension.
A reading of greater than __________ mmHg is indicative of hypertension.
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Match the types of hypertension with their definitions:
Match the types of hypertension with their definitions:
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What is a common factor contributing to primary hypertension?
What is a common factor contributing to primary hypertension?
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Masked hypertension can only be diagnosed through 24-hour ambulatory blood pressure monitoring.
Masked hypertension can only be diagnosed through 24-hour ambulatory blood pressure monitoring.
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Name a key factor that strongly indicates essential hypertension.
Name a key factor that strongly indicates essential hypertension.
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Blood pressure during ventricular contraction is called __________ blood pressure.
Blood pressure during ventricular contraction is called __________ blood pressure.
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Which statement about blood pressure is correct?
Which statement about blood pressure is correct?
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Which of the following increases peripheral resistance and raises blood pressure?
Which of the following increases peripheral resistance and raises blood pressure?
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Obesity is not considered a risk factor for hypertension.
Obesity is not considered a risk factor for hypertension.
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Name one common medication used as a first-line treatment for hypertension.
Name one common medication used as a first-line treatment for hypertension.
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The condition referred to as the 'silent killer' is __________.
The condition referred to as the 'silent killer' is __________.
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Match the hypertension complications with their potential effects:
Match the hypertension complications with their potential effects:
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Which of the following conditions is commonly associated with secondary hypertension?
Which of the following conditions is commonly associated with secondary hypertension?
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Cushing's syndrome leads to decreased sensitivity to catecholamines.
Cushing's syndrome leads to decreased sensitivity to catecholamines.
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What is one major treatment strategy for managing hypertensive emergencies?
What is one major treatment strategy for managing hypertensive emergencies?
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Hypertensive __________ occurs when blood pressure is above 180/120 with target organ damage.
Hypertensive __________ occurs when blood pressure is above 180/120 with target organ damage.
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What hormone increases sodium and water reabsorption, contributing to higher blood pressure?
What hormone increases sodium and water reabsorption, contributing to higher blood pressure?
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Which reading classifies as Stage 1 Hypertension?
Which reading classifies as Stage 1 Hypertension?
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Is isolated systolic hypertension characterized by elevated diastolic pressure?
Is isolated systolic hypertension characterized by elevated diastolic pressure?
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What is the primary mechanism contributing to primary hypertension?
What is the primary mechanism contributing to primary hypertension?
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Hypertension also known as the __________ killer.
Hypertension also known as the __________ killer.
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Match the following types of hypertension with their definitions:
Match the following types of hypertension with their definitions:
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What does a reading of 150/95 mmHg indicate?
What does a reading of 150/95 mmHg indicate?
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A reading of 120/80 mmHg is classified as elevated blood pressure.
A reading of 120/80 mmHg is classified as elevated blood pressure.
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What age group is most commonly associated with primary hypertension?
What age group is most commonly associated with primary hypertension?
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A blood pressure reading of 145/85 mmHg is classified as __________ hypertension.
A blood pressure reading of 145/85 mmHg is classified as __________ hypertension.
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Which monitoring technique is best for diagnosing masked hypertension?
Which monitoring technique is best for diagnosing masked hypertension?
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What is the primary role of norepinephrine in blood pressure regulation?
What is the primary role of norepinephrine in blood pressure regulation?
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Hyperparathyroidism is known to decrease vascular contraction.
Hyperparathyroidism is known to decrease vascular contraction.
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Name a common renal disorder that can cause secondary hypertension.
Name a common renal disorder that can cause secondary hypertension.
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The primary medication used in treating hypertensive emergencies is __________.
The primary medication used in treating hypertensive emergencies is __________.
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Match the endocrine causes of hypertension with their effects:
Match the endocrine causes of hypertension with their effects:
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Which of the following complications can be a result of uncontrolled hypertension?
Which of the following complications can be a result of uncontrolled hypertension?
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Hypertensive urgency occurs with target organ damage.
Hypertensive urgency occurs with target organ damage.
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What lifestyle modification is recommended for managing hypertension?
What lifestyle modification is recommended for managing hypertension?
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Increased blood pressure due to renal artery stenosis is classified as __________ hypertension.
Increased blood pressure due to renal artery stenosis is classified as __________ hypertension.
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What should be the target blood pressure reduction during the first hour of treating a hypertensive emergency?
What should be the target blood pressure reduction during the first hour of treating a hypertensive emergency?
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Which of the following is a lifestyle modification that can help manage hypertension?
Which of the following is a lifestyle modification that can help manage hypertension?
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Renal disorders are common causes of secondary hypertension.
Renal disorders are common causes of secondary hypertension.
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What is the primary purpose of the Renin-Angiotensin-Aldosterone System (RAAS) in hypertension?
What is the primary purpose of the Renin-Angiotensin-Aldosterone System (RAAS) in hypertension?
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_________ syndrome is characterized by muscle weakness and increased sensitivity to catecholamines, leading to hypertension.
_________ syndrome is characterized by muscle weakness and increased sensitivity to catecholamines, leading to hypertension.
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Match the endocrine causes of hypertension with their descriptions:
Match the endocrine causes of hypertension with their descriptions:
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Which medication is commonly used as a first-line treatment for hypertension?
Which medication is commonly used as a first-line treatment for hypertension?
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A hypertensive urgency implies that there is target organ damage.
A hypertensive urgency implies that there is target organ damage.
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Name one common neurological complication associated with uncontrolled hypertension.
Name one common neurological complication associated with uncontrolled hypertension.
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A ________ is often used as an intravenous agent for managing hypertensive emergencies.
A ________ is often used as an intravenous agent for managing hypertensive emergencies.
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Which of the following is NOT a risk factor for hypertension?
Which of the following is NOT a risk factor for hypertension?
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What defines elevated blood pressure?
What defines elevated blood pressure?
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Isolated systolic hypertension is characterized by elevated systolic pressure with normal diastolic pressure.
Isolated systolic hypertension is characterized by elevated systolic pressure with normal diastolic pressure.
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What is the significance of averaging blood pressure readings?
What is the significance of averaging blood pressure readings?
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Hypertension is often referred to as the __________ killer.
Hypertension is often referred to as the __________ killer.
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Match the types of hypertension with their definitions:
Match the types of hypertension with their definitions:
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Which factor is NOT associated with primary hypertension?
Which factor is NOT associated with primary hypertension?
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A reading of 141/89 mmHg indicates Stage 2 Hypertension.
A reading of 141/89 mmHg indicates Stage 2 Hypertension.
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Name one condition that can exhibit masked hypertension.
Name one condition that can exhibit masked hypertension.
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A reading of 130/85 mmHg is classified as __________ Hypertension.
A reading of 130/85 mmHg is classified as __________ Hypertension.
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During which phase is diastolic blood pressure measured?
During which phase is diastolic blood pressure measured?
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What reading indicates Stage 1 Hypertension?
What reading indicates Stage 1 Hypertension?
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Masked hypertension can only be diagnosed through 24-hour ambulatory blood pressure monitoring.
Masked hypertension can only be diagnosed through 24-hour ambulatory blood pressure monitoring.
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What is the systolic blood pressure during ventricular contraction called?
What is the systolic blood pressure during ventricular contraction called?
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A reading of greater than __________ mmHg is indicative of hypertension.
A reading of greater than __________ mmHg is indicative of hypertension.
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Match the hypertension types with their descriptions:
Match the hypertension types with their descriptions:
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Which of the following factors is a common risk indicator for primary hypertension?
Which of the following factors is a common risk indicator for primary hypertension?
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A diastolic reading of 90 mmHg qualifies as Stage 2 Hypertension.
A diastolic reading of 90 mmHg qualifies as Stage 2 Hypertension.
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What is a term for high blood pressure readings in a clinical setting but normal outside?
What is a term for high blood pressure readings in a clinical setting but normal outside?
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By averaging two blood pressure readings, the diagnosis of __________ can be more accurate.
By averaging two blood pressure readings, the diagnosis of __________ can be more accurate.
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Match the following blood pressure categories with their ranges:
Match the following blood pressure categories with their ranges:
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What is a common cause of secondary hypertension in young women?
What is a common cause of secondary hypertension in young women?
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Hypertensive urgency is defined as a blood pressure of 180/120 without target organ damage.
Hypertensive urgency is defined as a blood pressure of 180/120 without target organ damage.
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Name one potential neurological complication of uncontrolled hypertension.
Name one potential neurological complication of uncontrolled hypertension.
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Increased reabsorption of sodium and water from the adrenal cortex leads to __________ hypertension.
Increased reabsorption of sodium and water from the adrenal cortex leads to __________ hypertension.
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Match the following types of hypertension with their characteristics:
Match the following types of hypertension with their characteristics:
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Which of the following is a first-line medication for hypertension management?
Which of the following is a first-line medication for hypertension management?
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Aldosterone antagonists are beneficial in managing heart failure.
Aldosterone antagonists are beneficial in managing heart failure.
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What is the main purpose of lifestyle modifications in managing hypertension?
What is the main purpose of lifestyle modifications in managing hypertension?
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The __________ system plays a crucial role in regulating blood pressure via renin production.
The __________ system plays a crucial role in regulating blood pressure via renin production.
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Which complication is associated with chronic hypertension?
Which complication is associated with chronic hypertension?
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Study Notes
Definition of Hypertension
- Hypertension, or high blood pressure, is defined using guidelines from organizations like the American Heart Association.
- Diagnosis should be based on the average of two readings taken on two separate visits.
Blood Pressure Measurements
- Two key parameters are considered:
- Systolic Blood Pressure: Pressure during ventricular contraction (systole).
- Diastolic Blood Pressure: Pressure during ventricular relaxation (diastole).
Blood Pressure Categories
- Normal: Less than 120/80 mmHg.
- Elevated: 120-129 systolic and 80-89 diastolic mmHg.
- Stage 1 Hypertension: 130-139 systolic and 80-89 diastolic mmHg.
- Stage 2 Hypertension: Greater than 140 systolic or greater than 90 diastolic mmHg.
Types of Hypertension
- Isolated Systolic Hypertension: Elevated systolic (e.g., 135/74), with diastolic in normal range.
- Isolated Diastolic Hypertension: Elevated diastolic (e.g., 110/92), with systolic in normal range.
Special Considerations
-
White Coat Hypertension: High blood pressure in the doctor's office but normal readings outside.
- 24-hour ambulatory blood pressure monitoring can detect true blood pressure averages.
-
Masked Hypertension: Normal blood pressure in the office but elevated outside.
- Likewise, a 24-hour ambulatory blood pressure monitor helps in diagnosing this condition.
Key Diagnostic Criteria
- A reading of greater than 140/90 mmHg, especially after averaging two separate visits, is indicative of hypertension.### Primary Hypertension
- Definition: Essential or primary hypertension constitutes about 95% of hypertension cases.
- Age Factor: Most common in individuals aged 25-50 (sometimes up to 55).
- Family History: A strong indicator for essential hypertension diagnosis.
-
Mechanisms:
- Sympathetic Nervous System Activity: Increased norepinephrine and epinephrine lead to higher heart rates, increased cardiac output, and higher blood pressure.
- Cardiac Output: Increased heart rate and stroke volume elevate blood pressure.
- Vasoconstriction: Increased norepinephrine affects alpha-1 receptors, raising peripheral resistance and blood pressure.
- Renin-Angiotensin-Aldosterone System (RAAS): Elevated renin leads to increased angiotensin II, further raising blood pressure.
- Risk Factors: Obesity, high sodium intake, stress, smoking, high lipids, and sedentary lifestyle.
Secondary Hypertension
- Definition: Accounts for about 5% of hypertension, often seen in younger patients with sudden, severe refractory hypertension.
-
Common Causes:
- Renal Disorders: Including renal artery stenosis and fibromuscular dysplasia, particularly in young women.
- Diabetic Nephropathy: Associated with low glomerular filtration rates and elevated renin levels.
- Medication Review: Consider drugs such as sympathomimetics (cocaine, amphetamines) and oral contraceptives containing estrogen.
Endocrine Causes of Hypertension
-
Adrenal Issues:
- Hyperaldosteronism: Increased sodium and water reabsorption leads to higher blood volume and blood pressure.
- Cushing's Syndrome: Muscle weakness, "moon face," and increased sensitivity to catecholamines resulting in elevated blood pressure.
- Pheochromocytoma: Adrenal tumor secreting epinephrine and norepinephrine, leading to paroxysmal hypertension.
-
Thyroid Issues:
- Hyperthyroidism: Increases heart rate and output while decreasing vessel tone.
- Hypothyroidism: Increases vessel tone, raising peripheral resistance and blood pressure.
- Hyperparathyroidism: Elevated calcium levels in smooth muscles increase vascular contraction and blood pressure.
Cardiac Causes
- Coarctation of the Aorta: Results in high blood pressure in the upper body and low blood pressure in the lower body, often diagnosed through a discrepancy in pulses and blood pressures.
Complications of Hypertension
- Neurological: Increases risk of strokes, aneurysms, and hemorrhagic events due to vessel stress.
- Retinal Damage: Signs include AV nicking, cotton wool spots, and papilledema, indicating hypertensive retinopathy.
- Cardiac Complications: Risk of ischemic heart disease, left ventricular hypertrophy leading to heart failure, and arrhythmias (e.g., atrial fibrillation).
- Renal Complications: Chronic damage causing ischemia leading to renal failure, hematuria, and proteinuria (albuminuria).
Treatment of Hypertension
- Lifestyle Modifications: Weight loss, regular exercise, DASH diet, reduced sodium intake, and smoking cessation.
-
First-Line Medications:
- ACE Inhibitors (e.g., lisinopril): Beneficial for diabetes and chronic kidney disease patients but watch for cough and angioedema.
- ARBs (e.g., losartan): Similar benefits to ACE inhibitors, less cough risk.
- Dihydropyridine Calcium Channel Blockers (e.g., amlodipine): Useful for patients with low renin hypertension.
- Thiazide Diuretics (e.g., hydrochlorothiazide): Helpful for sodium retention, caution in gout patients.
-
Second-Line Medications:
- Beta Blockers: Indicated for coronary artery disease and heart failure; caution in asthma and hypotension.
- Aldosterone Antagonists (e.g., spironolactone): Beneficial in heart failure, monitor for hyperkalemia.
Hypertensive Crises
-
Definitions:
- Hypertensive Urgency: BP >180/120 without target organ damage.
- Hypertensive Emergency: BP >180/120 with target organ damage requiring immediate treatment.
- Management: IV antihypertensives; gradual BP reduction targeting 25% in the first hour, followed by less than 160/100 within 2-6 hours.
Work-Up for Secondary Hypertension
- Renal Evaluation: Ultrasound for renal artery stenosis or blood flow reduction.
- Cardiovascular Assessment: Check for coarctation signs and imaging.
- Endocrine Testing: Evaluate aldosterone, cortisol levels, and urinary metanephrines.
- Thyroid Assessment: TSH levels reflect hypo/hyperthyroidism.
- Pregnancy Considerations: Proteinuria testing for preeclampsia/eclampsia.
This structured overview encapsulates essential aspects of hypertension, its causes, complications, and management strategies.### Hypertensive Emergencies
- Rapid reduction of blood pressure from dangerously high levels (e.g., 220/140 mmHg to 120/80 mmHg) can lead to serious complications.
- Abrupt drops in blood pressure may result in ischemic events due to inadequate perfusion, leading to:
- Stroke from insufficient brain perfusion.
- Myocardial infarction (MI) from compromised coronary perfusion.
- Acute kidney injury from decreased renal perfusion.
Safe Blood Pressure Reduction
- It's critical to lower blood pressure slowly to mitigate risks associated with rapid changes.
- Common intravenous (IV) agents for controlled blood pressure management include:
- Nicardipine: A calcium channel blocker, widely used for hypertensive emergencies.
- Labetalol: A mixed alpha/beta-blocker, also frequently used.
Other IV Agents
- Additional medications that may be employed:
- Hydralazine: A vasodilator that can help lower blood pressure.
- Esmolol: A short-acting beta-blocker, beneficial in specific cases (e.g., aortic dissection).
- Nitroprusside: Although effective, it's not commonly used due to potential toxicity.
- Nitroglycerin: Useful in patients with left heart failure and pulmonary edema.
Importance of Hypertension Awareness
- Hypertension is a prevalent condition and often referred to as the "silent killer" due to its lack of symptoms.
- Understanding and recognizing hypertensive emergencies is crucial for preventing severe health consequences.
Definition of Hypertension
- Hypertension is defined as high blood pressure, following guidelines from the American Heart Association.
- Diagnoses rely on the average of two readings taken at separate visits.
Blood Pressure Measurements
- Systolic Blood Pressure: Measures pressure during heart ventricular contraction.
- Diastolic Blood Pressure: Measures pressure during heart ventricular relaxation.
Blood Pressure Categories
- Normal: Below 120/80 mmHg.
- Elevated: Systolic 120-129 and diastolic 80-89 mmHg.
- Stage 1 Hypertension: Systolic 130-139 and diastolic 80-89 mmHg.
- Stage 2 Hypertension: Systolic above 140 or diastolic above 90 mmHg.
Types of Hypertension
- Isolated Systolic Hypertension: Elevated systolic with normal diastolic levels.
- Isolated Diastolic Hypertension: Elevated diastolic with normal systolic levels.
Special Considerations
- White Coat Hypertension: High readings in the doctor's office but normal elsewhere.
- Masked Hypertension: Normal readings in the office but elevated outside.
- Both conditions can be evaluated with 24-hour ambulatory blood pressure monitoring.
Key Diagnostic Criteria
- Hypertension is indicated by readings above 140/90 mmHg, averaged over two visits.
Primary Hypertension
- Accounts for approximately 95% of all hypertension cases and is most common in individuals aged 25-55.
- Strongly linked to family history as a risk factor.
- Mechanisms include increased sympathetic nervous system activity, cardiac output, vasoconstriction, and the Renin-Angiotensin-Aldosterone System (RAAS).
- Risk factors: obesity, high sodium intake, stress, smoking, elevated lipids, and a sedentary lifestyle.
Secondary Hypertension
- Represents around 5% of cases, often presenting as sudden and severe hypertension.
- Common causes include renal disorders (renal artery stenosis, fibromuscular dysplasia), diabetic nephropathy, and certain medications.
Endocrine Causes of Hypertension
- Hyperaldosteronism: Increases blood volume due to sodium and water reabsorption.
- Cushing's Syndrome: Symptoms include muscle weakness and moon facies, leading to elevated blood pressure.
- Pheochromocytoma: An adrenal tumor increasing epinephrine and norepinephrine.
-
Thyroid Disorders:
- Hyperthyroidism: Heightened heart rate and lowered vessel tone.
- Hypothyroidism: Increased vessel tone leading to higher resistance.
- Hyperparathyroidism: Elevated calcium levels increase vascular contraction.
Cardiac Causes
- Coarctation of the Aorta: Presents with high upper body blood pressure and low lower body pressure, identified through pulse discrepancy.
Complications of Hypertension
- Neurological Risks: Higher chances of strokes, aneurysms, and hemorrhagic events.
- Retinal Damage: Indicators include AV nicking and cotton wool spots.
- Cardiac Complications: Increased risk of ischemic heart disease and heart failure.
- Renal Complications: Can lead to chronic renal failure and related symptoms.
Treatment of Hypertension
- Lifestyle Modifications: Focus on weight loss, exercise, DASH diet, reduced sodium, and quitting smoking.
-
First-Line Medications:
- ACE Inhibitors: Effective for diabetes patients but may cause cough.
- ARBs: Similar to ACE inhibitors, less cough risk.
- Calcium Channel Blockers: Effective for specific hypertension types.
- Thiazide Diuretics: Caution advised in gout patients.
-
Second-Line Medications:
- Beta Blockers: Useful for coronary artery disease.
- Aldosterone Antagonists: Watch for hyperkalemia risks.
Hypertensive Crises
- Definitions:
- Hypertensive Urgency: Blood pressure above 180/120 without organ damage.
- Hypertensive Emergency: Blood pressure above 180/120 with organ damage.
- Management involves gradual blood pressure reduction using IV antihypertensives, targeting 25% reduction in the first hour.
Work-Up for Secondary Hypertension
- Renal Assessment: Ultrasound to check for disorders like renal artery stenosis.
- Cardiovascular Evaluation: Check for signs of coarctation.
- Endocrine Testing: Assess hormone levels such as aldosterone and cortisol.
- Thyroid Assessment: Measure TSH levels.
- Consider testing for preeclampsia during pregnancy.
Importance of Hypertension Awareness
- Recognized as the "silent killer" for its asymptomatic nature; understanding emergencies is crucial for health outcomes.
Definition of Hypertension
- Hypertension is defined as high blood pressure, following guidelines from the American Heart Association.
- Diagnoses rely on the average of two readings taken at separate visits.
Blood Pressure Measurements
- Systolic Blood Pressure: Measures pressure during heart ventricular contraction.
- Diastolic Blood Pressure: Measures pressure during heart ventricular relaxation.
Blood Pressure Categories
- Normal: Below 120/80 mmHg.
- Elevated: Systolic 120-129 and diastolic 80-89 mmHg.
- Stage 1 Hypertension: Systolic 130-139 and diastolic 80-89 mmHg.
- Stage 2 Hypertension: Systolic above 140 or diastolic above 90 mmHg.
Types of Hypertension
- Isolated Systolic Hypertension: Elevated systolic with normal diastolic levels.
- Isolated Diastolic Hypertension: Elevated diastolic with normal systolic levels.
Special Considerations
- White Coat Hypertension: High readings in the doctor's office but normal elsewhere.
- Masked Hypertension: Normal readings in the office but elevated outside.
- Both conditions can be evaluated with 24-hour ambulatory blood pressure monitoring.
Key Diagnostic Criteria
- Hypertension is indicated by readings above 140/90 mmHg, averaged over two visits.
Primary Hypertension
- Accounts for approximately 95% of all hypertension cases and is most common in individuals aged 25-55.
- Strongly linked to family history as a risk factor.
- Mechanisms include increased sympathetic nervous system activity, cardiac output, vasoconstriction, and the Renin-Angiotensin-Aldosterone System (RAAS).
- Risk factors: obesity, high sodium intake, stress, smoking, elevated lipids, and a sedentary lifestyle.
Secondary Hypertension
- Represents around 5% of cases, often presenting as sudden and severe hypertension.
- Common causes include renal disorders (renal artery stenosis, fibromuscular dysplasia), diabetic nephropathy, and certain medications.
Endocrine Causes of Hypertension
- Hyperaldosteronism: Increases blood volume due to sodium and water reabsorption.
- Cushing's Syndrome: Symptoms include muscle weakness and moon facies, leading to elevated blood pressure.
- Pheochromocytoma: An adrenal tumor increasing epinephrine and norepinephrine.
-
Thyroid Disorders:
- Hyperthyroidism: Heightened heart rate and lowered vessel tone.
- Hypothyroidism: Increased vessel tone leading to higher resistance.
- Hyperparathyroidism: Elevated calcium levels increase vascular contraction.
Cardiac Causes
- Coarctation of the Aorta: Presents with high upper body blood pressure and low lower body pressure, identified through pulse discrepancy.
Complications of Hypertension
- Neurological Risks: Higher chances of strokes, aneurysms, and hemorrhagic events.
- Retinal Damage: Indicators include AV nicking and cotton wool spots.
- Cardiac Complications: Increased risk of ischemic heart disease and heart failure.
- Renal Complications: Can lead to chronic renal failure and related symptoms.
Treatment of Hypertension
- Lifestyle Modifications: Focus on weight loss, exercise, DASH diet, reduced sodium, and quitting smoking.
-
First-Line Medications:
- ACE Inhibitors: Effective for diabetes patients but may cause cough.
- ARBs: Similar to ACE inhibitors, less cough risk.
- Calcium Channel Blockers: Effective for specific hypertension types.
- Thiazide Diuretics: Caution advised in gout patients.
-
Second-Line Medications:
- Beta Blockers: Useful for coronary artery disease.
- Aldosterone Antagonists: Watch for hyperkalemia risks.
Hypertensive Crises
- Definitions:
- Hypertensive Urgency: Blood pressure above 180/120 without organ damage.
- Hypertensive Emergency: Blood pressure above 180/120 with organ damage.
- Management involves gradual blood pressure reduction using IV antihypertensives, targeting 25% reduction in the first hour.
Work-Up for Secondary Hypertension
- Renal Assessment: Ultrasound to check for disorders like renal artery stenosis.
- Cardiovascular Evaluation: Check for signs of coarctation.
- Endocrine Testing: Assess hormone levels such as aldosterone and cortisol.
- Thyroid Assessment: Measure TSH levels.
- Consider testing for preeclampsia during pregnancy.
Importance of Hypertension Awareness
- Recognized as the "silent killer" for its asymptomatic nature; understanding emergencies is crucial for health outcomes.
Definition of Hypertension
- Hypertension is defined as high blood pressure, following guidelines from the American Heart Association.
- Diagnoses rely on the average of two readings taken at separate visits.
Blood Pressure Measurements
- Systolic Blood Pressure: Measures pressure during heart ventricular contraction.
- Diastolic Blood Pressure: Measures pressure during heart ventricular relaxation.
Blood Pressure Categories
- Normal: Below 120/80 mmHg.
- Elevated: Systolic 120-129 and diastolic 80-89 mmHg.
- Stage 1 Hypertension: Systolic 130-139 and diastolic 80-89 mmHg.
- Stage 2 Hypertension: Systolic above 140 or diastolic above 90 mmHg.
Types of Hypertension
- Isolated Systolic Hypertension: Elevated systolic with normal diastolic levels.
- Isolated Diastolic Hypertension: Elevated diastolic with normal systolic levels.
Special Considerations
- White Coat Hypertension: High readings in the doctor's office but normal elsewhere.
- Masked Hypertension: Normal readings in the office but elevated outside.
- Both conditions can be evaluated with 24-hour ambulatory blood pressure monitoring.
Key Diagnostic Criteria
- Hypertension is indicated by readings above 140/90 mmHg, averaged over two visits.
Primary Hypertension
- Accounts for approximately 95% of all hypertension cases and is most common in individuals aged 25-55.
- Strongly linked to family history as a risk factor.
- Mechanisms include increased sympathetic nervous system activity, cardiac output, vasoconstriction, and the Renin-Angiotensin-Aldosterone System (RAAS).
- Risk factors: obesity, high sodium intake, stress, smoking, elevated lipids, and a sedentary lifestyle.
Secondary Hypertension
- Represents around 5% of cases, often presenting as sudden and severe hypertension.
- Common causes include renal disorders (renal artery stenosis, fibromuscular dysplasia), diabetic nephropathy, and certain medications.
Endocrine Causes of Hypertension
- Hyperaldosteronism: Increases blood volume due to sodium and water reabsorption.
- Cushing's Syndrome: Symptoms include muscle weakness and moon facies, leading to elevated blood pressure.
- Pheochromocytoma: An adrenal tumor increasing epinephrine and norepinephrine.
-
Thyroid Disorders:
- Hyperthyroidism: Heightened heart rate and lowered vessel tone.
- Hypothyroidism: Increased vessel tone leading to higher resistance.
- Hyperparathyroidism: Elevated calcium levels increase vascular contraction.
Cardiac Causes
- Coarctation of the Aorta: Presents with high upper body blood pressure and low lower body pressure, identified through pulse discrepancy.
Complications of Hypertension
- Neurological Risks: Higher chances of strokes, aneurysms, and hemorrhagic events.
- Retinal Damage: Indicators include AV nicking and cotton wool spots.
- Cardiac Complications: Increased risk of ischemic heart disease and heart failure.
- Renal Complications: Can lead to chronic renal failure and related symptoms.
Treatment of Hypertension
- Lifestyle Modifications: Focus on weight loss, exercise, DASH diet, reduced sodium, and quitting smoking.
-
First-Line Medications:
- ACE Inhibitors: Effective for diabetes patients but may cause cough.
- ARBs: Similar to ACE inhibitors, less cough risk.
- Calcium Channel Blockers: Effective for specific hypertension types.
- Thiazide Diuretics: Caution advised in gout patients.
-
Second-Line Medications:
- Beta Blockers: Useful for coronary artery disease.
- Aldosterone Antagonists: Watch for hyperkalemia risks.
Hypertensive Crises
- Definitions:
- Hypertensive Urgency: Blood pressure above 180/120 without organ damage.
- Hypertensive Emergency: Blood pressure above 180/120 with organ damage.
- Management involves gradual blood pressure reduction using IV antihypertensives, targeting 25% reduction in the first hour.
Work-Up for Secondary Hypertension
- Renal Assessment: Ultrasound to check for disorders like renal artery stenosis.
- Cardiovascular Evaluation: Check for signs of coarctation.
- Endocrine Testing: Assess hormone levels such as aldosterone and cortisol.
- Thyroid Assessment: Measure TSH levels.
- Consider testing for preeclampsia during pregnancy.
Importance of Hypertension Awareness
- Recognized as the "silent killer" for its asymptomatic nature; understanding emergencies is crucial for health outcomes.
Definition of Hypertension
- Hypertension is defined as high blood pressure, following guidelines from the American Heart Association.
- Diagnoses rely on the average of two readings taken at separate visits.
Blood Pressure Measurements
- Systolic Blood Pressure: Measures pressure during heart ventricular contraction.
- Diastolic Blood Pressure: Measures pressure during heart ventricular relaxation.
Blood Pressure Categories
- Normal: Below 120/80 mmHg.
- Elevated: Systolic 120-129 and diastolic 80-89 mmHg.
- Stage 1 Hypertension: Systolic 130-139 and diastolic 80-89 mmHg.
- Stage 2 Hypertension: Systolic above 140 or diastolic above 90 mmHg.
Types of Hypertension
- Isolated Systolic Hypertension: Elevated systolic with normal diastolic levels.
- Isolated Diastolic Hypertension: Elevated diastolic with normal systolic levels.
Special Considerations
- White Coat Hypertension: High readings in the doctor's office but normal elsewhere.
- Masked Hypertension: Normal readings in the office but elevated outside.
- Both conditions can be evaluated with 24-hour ambulatory blood pressure monitoring.
Key Diagnostic Criteria
- Hypertension is indicated by readings above 140/90 mmHg, averaged over two visits.
Primary Hypertension
- Accounts for approximately 95% of all hypertension cases and is most common in individuals aged 25-55.
- Strongly linked to family history as a risk factor.
- Mechanisms include increased sympathetic nervous system activity, cardiac output, vasoconstriction, and the Renin-Angiotensin-Aldosterone System (RAAS).
- Risk factors: obesity, high sodium intake, stress, smoking, elevated lipids, and a sedentary lifestyle.
Secondary Hypertension
- Represents around 5% of cases, often presenting as sudden and severe hypertension.
- Common causes include renal disorders (renal artery stenosis, fibromuscular dysplasia), diabetic nephropathy, and certain medications.
Endocrine Causes of Hypertension
- Hyperaldosteronism: Increases blood volume due to sodium and water reabsorption.
- Cushing's Syndrome: Symptoms include muscle weakness and moon facies, leading to elevated blood pressure.
- Pheochromocytoma: An adrenal tumor increasing epinephrine and norepinephrine.
-
Thyroid Disorders:
- Hyperthyroidism: Heightened heart rate and lowered vessel tone.
- Hypothyroidism: Increased vessel tone leading to higher resistance.
- Hyperparathyroidism: Elevated calcium levels increase vascular contraction.
Cardiac Causes
- Coarctation of the Aorta: Presents with high upper body blood pressure and low lower body pressure, identified through pulse discrepancy.
Complications of Hypertension
- Neurological Risks: Higher chances of strokes, aneurysms, and hemorrhagic events.
- Retinal Damage: Indicators include AV nicking and cotton wool spots.
- Cardiac Complications: Increased risk of ischemic heart disease and heart failure.
- Renal Complications: Can lead to chronic renal failure and related symptoms.
Treatment of Hypertension
- Lifestyle Modifications: Focus on weight loss, exercise, DASH diet, reduced sodium, and quitting smoking.
-
First-Line Medications:
- ACE Inhibitors: Effective for diabetes patients but may cause cough.
- ARBs: Similar to ACE inhibitors, less cough risk.
- Calcium Channel Blockers: Effective for specific hypertension types.
- Thiazide Diuretics: Caution advised in gout patients.
-
Second-Line Medications:
- Beta Blockers: Useful for coronary artery disease.
- Aldosterone Antagonists: Watch for hyperkalemia risks.
Hypertensive Crises
- Definitions:
- Hypertensive Urgency: Blood pressure above 180/120 without organ damage.
- Hypertensive Emergency: Blood pressure above 180/120 with organ damage.
- Management involves gradual blood pressure reduction using IV antihypertensives, targeting 25% reduction in the first hour.
Work-Up for Secondary Hypertension
- Renal Assessment: Ultrasound to check for disorders like renal artery stenosis.
- Cardiovascular Evaluation: Check for signs of coarctation.
- Endocrine Testing: Assess hormone levels such as aldosterone and cortisol.
- Thyroid Assessment: Measure TSH levels.
- Consider testing for preeclampsia during pregnancy.
Importance of Hypertension Awareness
- Recognized as the "silent killer" for its asymptomatic nature; understanding emergencies is crucial for health outcomes.
Definition of Hypertension
- Hypertension is defined as high blood pressure, following guidelines from the American Heart Association.
- Diagnoses rely on the average of two readings taken at separate visits.
Blood Pressure Measurements
- Systolic Blood Pressure: Measures pressure during heart ventricular contraction.
- Diastolic Blood Pressure: Measures pressure during heart ventricular relaxation.
Blood Pressure Categories
- Normal: Below 120/80 mmHg.
- Elevated: Systolic 120-129 and diastolic 80-89 mmHg.
- Stage 1 Hypertension: Systolic 130-139 and diastolic 80-89 mmHg.
- Stage 2 Hypertension: Systolic above 140 or diastolic above 90 mmHg.
Types of Hypertension
- Isolated Systolic Hypertension: Elevated systolic with normal diastolic levels.
- Isolated Diastolic Hypertension: Elevated diastolic with normal systolic levels.
Special Considerations
- White Coat Hypertension: High readings in the doctor's office but normal elsewhere.
- Masked Hypertension: Normal readings in the office but elevated outside.
- Both conditions can be evaluated with 24-hour ambulatory blood pressure monitoring.
Key Diagnostic Criteria
- Hypertension is indicated by readings above 140/90 mmHg, averaged over two visits.
Primary Hypertension
- Accounts for approximately 95% of all hypertension cases and is most common in individuals aged 25-55.
- Strongly linked to family history as a risk factor.
- Mechanisms include increased sympathetic nervous system activity, cardiac output, vasoconstriction, and the Renin-Angiotensin-Aldosterone System (RAAS).
- Risk factors: obesity, high sodium intake, stress, smoking, elevated lipids, and a sedentary lifestyle.
Secondary Hypertension
- Represents around 5% of cases, often presenting as sudden and severe hypertension.
- Common causes include renal disorders (renal artery stenosis, fibromuscular dysplasia), diabetic nephropathy, and certain medications.
Endocrine Causes of Hypertension
- Hyperaldosteronism: Increases blood volume due to sodium and water reabsorption.
- Cushing's Syndrome: Symptoms include muscle weakness and moon facies, leading to elevated blood pressure.
- Pheochromocytoma: An adrenal tumor increasing epinephrine and norepinephrine.
-
Thyroid Disorders:
- Hyperthyroidism: Heightened heart rate and lowered vessel tone.
- Hypothyroidism: Increased vessel tone leading to higher resistance.
- Hyperparathyroidism: Elevated calcium levels increase vascular contraction.
Cardiac Causes
- Coarctation of the Aorta: Presents with high upper body blood pressure and low lower body pressure, identified through pulse discrepancy.
Complications of Hypertension
- Neurological Risks: Higher chances of strokes, aneurysms, and hemorrhagic events.
- Retinal Damage: Indicators include AV nicking and cotton wool spots.
- Cardiac Complications: Increased risk of ischemic heart disease and heart failure.
- Renal Complications: Can lead to chronic renal failure and related symptoms.
Treatment of Hypertension
- Lifestyle Modifications: Focus on weight loss, exercise, DASH diet, reduced sodium, and quitting smoking.
-
First-Line Medications:
- ACE Inhibitors: Effective for diabetes patients but may cause cough.
- ARBs: Similar to ACE inhibitors, less cough risk.
- Calcium Channel Blockers: Effective for specific hypertension types.
- Thiazide Diuretics: Caution advised in gout patients.
-
Second-Line Medications:
- Beta Blockers: Useful for coronary artery disease.
- Aldosterone Antagonists: Watch for hyperkalemia risks.
Hypertensive Crises
- Definitions:
- Hypertensive Urgency: Blood pressure above 180/120 without organ damage.
- Hypertensive Emergency: Blood pressure above 180/120 with organ damage.
- Management involves gradual blood pressure reduction using IV antihypertensives, targeting 25% reduction in the first hour.
Work-Up for Secondary Hypertension
- Renal Assessment: Ultrasound to check for disorders like renal artery stenosis.
- Cardiovascular Evaluation: Check for signs of coarctation.
- Endocrine Testing: Assess hormone levels such as aldosterone and cortisol.
- Thyroid Assessment: Measure TSH levels.
- Consider testing for preeclampsia during pregnancy.
Importance of Hypertension Awareness
- Recognized as the "silent killer" for its asymptomatic nature; understanding emergencies is crucial for health outcomes.
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Description
This quiz provides insights into the definition and measurement of hypertension. It covers key parameters, categories, and types of high blood pressure according to guidelines by health organizations. Test your knowledge on systolic and diastolic pressure readings along with their classifications.