Hypertension: Pathophysiology & Risk Factors

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Questions and Answers

A patient presents with hypertension, and their medical history reveals long-term kidney disease. Which type of hypertension are they most likely experiencing?

  • Secondary hypertension, resulting from the kidney disease. (correct)
  • Isolated systolic hypertension, common in older adults.
  • Primary hypertension, due to the idiopathic nature of the condition.
  • Resistant hypertension, requiring multiple medications for control.

Which mechanism directly contributes to increased peripheral resistance in hypertension?

  • Atherosclerosis leading to narrowed arterial diameter. (correct)
  • Vasodilation caused by nitric oxide deficiency.
  • Increased stroke volume and reduced cardiac contractility.
  • Decreased blood viscosity and enhanced vascular compliance.

A patient with primary hypertension is advised to modify their lifestyle. Which combination of changes would be most effective in managing their blood pressure?

  • Maintain current diet and begin taking over-the-counter decongestants.
  • Start smoking to relieve stress and lower cholesterol through diet alone.
  • Increase sodium intake and reduce physical activity.
  • Reduce sodium intake, increase physical activity, and manage stress. (correct)

Which of the following conditions is least likely to be a cause of secondary hypertension?

<p>Osteoporosis (C)</p> Signup and view all the answers

How does uncontrolled hypertension increase the risk of myocardial infarction (heart attack)?

<p>By damaging blood vessels and forcing the heart to work harder, leading to potential ischemia. (C)</p> Signup and view all the answers

A patient with a family history of hypertension, obesity, and a sedentary lifestyle is diagnosed with elevated blood pressure. Which type of hypertension is the patient most likely experiencing?

<p>Primary hypertension (A)</p> Signup and view all the answers

Which of the following mechanisms is most directly responsible for the increased cardiac workload associated with long-term uncontrolled hypertension?

<p>Elevated afterload (B)</p> Signup and view all the answers

A patient's blood pressure remains elevated despite adhering to a low-sodium diet and engaging in regular exercise. Further testing reveals the presence of a previously undiagnosed endocrine disorder. Which condition is most likely contributing to the patient's hypertension?

<p>Hypothyroidism (B)</p> Signup and view all the answers

A researcher is studying the long-term effects of hypertension on cardiovascular health. Which of the following pathological changes is most directly linked to increased risk of heart failure in hypertensive patients?

<p>Left ventricular hypertrophy (D)</p> Signup and view all the answers

A patient with a history of controlled hypertension is prescribed a new medication for an unrelated condition. Shortly after starting the new medication, their blood pressure becomes significantly elevated. Which class of medications is most likely to have caused this effect?

<p>Nonsteroidal anti-inflammatory drugs (NSAIDs) (C)</p> Signup and view all the answers

Flashcards

Hypertension

High blood pressure.

Hypertension Pathophysiology

Increased peripheral resistance and/or increased cardiac output.

Atherosclerosis in Hypertension

Hardening and narrowing of the arteries, contributing to increased peripheral resistance.

Primary Hypertension

Hypertension arising spontaneously or from unknown cause; most common type.

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Secondary Hypertension

Hypertension caused by another disease or medication.

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Peripheral Resistance

Increased resistance in blood vessels, making the heart work harder.

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Cardiac Output

The amount of blood the heart pumps per minute.

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Hypertension Effects

Heart has to pump harder; can damage heart and blood vessels.

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Primary Hypertension Risk Factors

Family history, high sodium, obesity, smoking, stress, high cholesterol.

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Causes of Secondary Hypertension

Kidney disease, hypothyroidism, Cushing's syndrome, pheochromocytoma.

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Study Notes

  • Hypertension is high blood pressure
  • Hypertension pathophysiology involves increased peripheral resistance and/or increased cardiac output
  • Increased peripheral resistance may be due to atherosclerosis
  • Atherosclerosis is a contributing factor in many hypertension cases
  • Hypertension forces the heart to work harder to pump blood
  • Over time, hypertension can damage the heart and blood vessels
  • Hypertension increases the risk of myocardial infarction (heart attack) or stroke

Primary vs. Secondary Hypertension

  • Primary and secondary hypertension differ based on cause or risk factors

Risk Factors of Hypertension

  • Risk factors vary depending on whether it's primary or secondary hypertension

Primary Hypertension

  • Also called essential hypertension, it is the most common type
  • It arises spontaneously or from an unknown cause (idiopathic)
  • Primary hypertension is high blood pressure by itself, not caused by another disease
  • Risk factors include family history, high sodium intake, obesity, smoking, stress, and hyperlipidemia (high cholesterol)

Secondary Hypertension

  • Secondary hypertension is caused by a disease or a medication
  • Potential causes include kidney disease, hypothyroidism, Cushing's syndrome, and pheochromocytoma

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