10 Questions
Which immunoglobulin is typically involved in Type I hypersensitivity reactions?
IgE
What is the term for nonparasite antigens that can trigger a Type I hypersensitivity response?
Allergens
Which enzyme allergen is found in the fecal pellets of the common dust mite and is aerosolized easily?
Der P1
What genetic trait predisposes individuals to localized anaphylaxis?
Atopy
Which of the following is NOT a candidate polymorphic gene associated with Type I hypersensitivity?
IL-6 Receptor
What is the main function of Class II MHC in relation to allergic responses?
Present peptides promoting Th2 response
What is the role of Fc epsilon receptors (FceR1) on mast cells in allergic responses?
Degranulate the mast cells
What is the immediate effect of histamine release during Type I Hypersensitivity reactions?
Constriction of smooth muscles causing wheezing
How does attachment to Fc receptors affect the lifespan of IgE?
Increases its lifespan to months compared to days in serum
What is the role of high affinity IgE Fc receptor (FceR1) during allergic responses?
Enhance cross-linking of IgE on mast cells
Test your knowledge about hypersensitivity reactions and type I hypersensitivity reactions mediated by IgE, with symptoms like anaphylaxis and conditions like hay fever, asthma, and food allergies.
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