Hypersensitivity and Type I Hypersensitivity Quiz
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Questions and Answers

Which immunoglobulin is typically involved in Type I hypersensitivity reactions?

  • IgG
  • IgM
  • IgA
  • IgE (correct)
  • What is the term for nonparasite antigens that can trigger a Type I hypersensitivity response?

  • Toxins
  • Allergens (correct)
  • Antibodies
  • Pathogens
  • Which enzyme allergen is found in the fecal pellets of the common dust mite and is aerosolized easily?

  • Der P4
  • Der P3
  • Der P2
  • Der P1 (correct)
  • What genetic trait predisposes individuals to localized anaphylaxis?

    <p>Atopy</p> Signup and view all the answers

    Which of the following is NOT a candidate polymorphic gene associated with Type I hypersensitivity?

    <p>IL-6 Receptor</p> Signup and view all the answers

    What is the main function of Class II MHC in relation to allergic responses?

    <p>Present peptides promoting Th2 response</p> Signup and view all the answers

    What is the role of Fc epsilon receptors (FceR1) on mast cells in allergic responses?

    <p>Degranulate the mast cells</p> Signup and view all the answers

    What is the immediate effect of histamine release during Type I Hypersensitivity reactions?

    <p>Constriction of smooth muscles causing wheezing</p> Signup and view all the answers

    How does attachment to Fc receptors affect the lifespan of IgE?

    <p>Increases its lifespan to months compared to days in serum</p> Signup and view all the answers

    What is the role of high affinity IgE Fc receptor (FceR1) during allergic responses?

    <p>Enhance cross-linking of IgE on mast cells</p> Signup and view all the answers

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