Hyperlipidemia Drugs

A 62-year-old male with a history of hypertension and type 2 diabetes mellitus has an LDL-C level of 170 mg/dL despite lifestyle modifications. His 10-year ASCVD risk score is calculated to be 12%. According to the guidelines, what is the most appropriate initial treatment?

Which of the following is the primary mechanism of action of HMG-CoA reductase inhibitors (statins)?

A 58-year-old female is started on atorvastatin for hyperlipidemia. Which laboratory value is most important to check before initiating statin therapy?

Which of the following statins is considered a high-intensity statin at commonly prescribed doses?

A patient on warfarin is prescribed gemfibrozil for hypertriglyceridemia. What potential interaction should the healthcare provider monitor for?

Which of the following is a common side effect of niacin, and what strategy can be used to mitigate it?

A 45-year-old patient with a history of premature coronary artery disease (CAD) presents with an LDL-C level of 180 mg/dL despite being on a moderate-intensity statin. What is the next best step in management?

Which lipid-lowering agent is most effective at lowering triglyceride levels?

Which of the following is a contraindication to the use of HMG-CoA reductase inhibitors (statins)?

A patient taking simvastatin reports muscle pain and weakness. What is the most appropriate initial action?

Which of the following best describes the action of omega-3 fatty acids in managing hypertriglyceridemia?

A patient with severe hypertriglyceridemia (TG > 500 mg/dL) is started on fenofibrate. What potential adverse effect should the patient be educated about?

Which of the following lipid-lowering medications is a prodrug?

A 68-year-old patient with known coronary artery disease (CAD) has an LDL-C level of 85 mg/dL despite being on a high-intensity statin. According to current guidelines, what should be considered?

Which of the following laboratory values should be monitored in patients taking niacin?

Which of the following patients would be the best candidate for bile acid sequestrants?

A patient with a history of ASCVD has been on maximally tolerated statin therapy for several years, achieving a 40% reduction in LDL-C. His LDL-C remains above target. Which of the following would be the most appropriate next step?

A patient is started on cholestyramine. To avoid drug interactions, when should other medications be administered?

Which of the following patients with hyperlipidemia would be LEAST likely to benefit from statin therapy?

Which of the following is a risk factor for myopathy and rhabdomyolysis in patients taking statins?

A 70-year-old patient has an LDL-C level of 150 mg/dL and is started on simvastatin 20 mg daily. After 6 weeks, LDL-C is 120 mg/dL. What is the next appropriate step?

A 55-year-old male with a history of hypertension and a 10-year ASCVD risk of 8% has an LDL-C of 140 mg/dL. Which of the following is the MOST appropriate recommendation, according to current guidelines?

Which of the following is a potential benefit of using a cholesterol absorption inhibitor like ezetimibe in addition to a statin?

Which of the following is considered a risk-enhancing factor that may favor the initiation of statin therapy in individuals with borderline to intermediate ASCVD risk?

Which of the following statins is a prodrug that requires hydrolysis to its active form?

Which of the following medications is most effective for lowering LDL cholesterol?

A patient with severe hypertriglyceridemia (TG > 500 mg/dL) should be started on which therapy?

Which of the following statin doses is considered high-intensity?

A 55-year-old patient with an ASCVD score of 10% and no history of cardiovascular disease should be started on which therapy?

A patient taking niacin reports significant flushing. What can help reduce this side effect?

Which drug class is the most effective at increasing HDL levels?

A 45-year-old with diabetes and an ASCVD score of 6% should be started on which therapy?

Which of the following side effects is most concerning in a patient taking a statin?

Which lab should be checked prior to initiating statin therapy?

A patient on maximally tolerated statin therapy still has high LDL. What is the next step?

Which lab test is the most important to monitor for statin-induced myopathy?

Which of the following lipid-lowering drugs increases the anticoagulant effect of warfarin?

Which lipid-lowering medication is contraindicated in pregnancy?

Which of the following patients should be started on high-intensity statin therapy?

Which medication is most effective at lowering LDL cholesterol?

Which statement about omega-3 fatty acids is correct?

Which of the following is a known adverse effect of statins?

Which of the following is NOT a major risk factor for hyperlipidemia?

Which lipid-lowering agent can increase the effect of warfarin, increasing the risk of bleeding?

Which lipid-lowering medication is absolutely contraindicated in pregnancy?

A patient on a high-intensity statin still has an elevated LDL. What is the preferred add-on therapy?

Which of the following medications is most effective for lowering triglycerides?

Which statement about PCSK9 inhibitors is correct?

What is the mechanism of action of ezetimibe?