Hyperlipidemia: Lipids and Lipoproteins

Which lipoprotein is secreted from the liver to carry endogenous triglycerides into the blood circulation?

Which lipoprotein carries cholesterol from peripheral tissues and blood circulation to the liver for metabolism and/or secretion?

Which lipoprotein is secreted from the liver to carry endogenous cholesterol into the blood circulation?

What is correlated with coronary heart disease?

Which lipoprotein is listed as the most atherogenic?

What consists mostly of lipoproteins?

Which combination is a lipoprotein?

Which type of cholesterol is commonly referred to as 'bad' cholesterol?

Which type of lipoprotein removes cholesterol from the bloodstream?

Which lipoprotein carries cholesterol from peripheral tissues and blood circulation to the liver for metabolism and/or secretion?

Which type of lipoprotein is secreted from the liver to carry endogenous triglycerides into the blood circulation?

What is the primary mechanism of action of HMG CoA reductase inhibitors such as statins?

Which of the following is NOT a commonly known statin?

What effect do HMG CoA reductase inhibitors have on triglyceride levels?

What is the primary function of cell surface LDL receptors in the context of HMG CoA reductase inhibitors?

What is the recommended time of day for giving statins?

What adverse effect is associated with statins?

What is the effect of statins on pregnancy?

What potential interaction may occur when using statins?

Statins are the primary treatment option for hypercholesterolemia.

Statins should be given in the morning because major cholesterol synthesis happens at that time.

Pregnant and lactating women can safely take statins.

Elevated liver enzymes and myopathy are adverse effects associated with statins.

What is the most effective effect of niacin on lipoproteins?

Which adverse effect is commonly associated with the use of niacin?

What is the mechanism of action of niacin?

What is the recommended action to prevent the intense cutaneous flush associated with niacin use?

In what condition should niacin be avoided or given with caution when used in combination with statins?

What is the therapeutic use of niacin in the treatment of familial hyperlipidemias?

Niacin reduces LDL C by 20%.

Niacin lowers triglycerides by 35%.

Niacin is the most effective agent for increasing HDL C.

Niacin inhibits lipolysis in adipose tissue, reducing production of free fatty acids.

Niacin is useful in the treatment of familial hyperlipidemias.

Niacin should be avoided in hepatic disease and used with caution with statins.

What is the mechanism of action of fenofibrate and gemfibrozil in regulating lipid metabolism?

Which medication is most efficacious in lowering triglycerides?

What is the primary therapeutic use of fibrates like fenofibrate and gemfibrozil?

What effect do fibrates like fenofibrate and gemfibrozil have on triglyceride concentrations?

What is the most common adverse effect associated with fibrate use?

Which adverse effect may occur in patients taking gemfibrozil and statins together?

What is the primary therapeutic use of niacin?

What is the mechanism of action of fenofibrate and gemfibrozil in regulating lipid metabolism?

What is the mechanism of action of bile acid binding resins?

What is the primary effect of bile acid binding resins on intracellular cholesterol concentrations?

What is the primary benefit observed with bile acid binding resins in terms of lipid management?

Which process is directly affected by the formation of a resin/bile acid complex with bile acid binding resins?

What is the primary mechanism of action of bile acid binding resins?

What is the most common side effect associated with the use of bile acid binding resins?

What is the primary therapeutic use of bile acid binding resins?

What effect do bile acid binding resins have on triglyceride levels?

Bile acid binding resins are often used in combination with diet or niacin for treating type IIA and type IIB hyperlipidemias.

Bile acid sequestrants are absorbed and metabolically altered by the intestine after oral administration.

The most common side effects of bile acid binding resins include constipation, nausea, and flatulence.

Bile acid binding resins may impair the absorption of fat soluble vitamins and interfere with the absorption of many drugs.

Bile acid binding resins are absorbed and metabolically altered by the intestine after oral administration.

Niacin is indicated for type 2 diabetes due to its glucose lowering effects.

Bile acid binding resins may raise triglyceride levels and are contraindicated in patients with significant hypertriglyceridemia.

The most common side effects of bile acid binding resins include impaired absorption of fat-soluble vitamins (A, D, E, and K).

Ezetimibe selectively inhibits absorption of dietary and biliary cholesterol in the small intestine.

Niacin inhibits lipolysis in adipose tissue, reducing production of free fatty acids.

Bile acid binding resins are absorbed and metabolically altered by the intestine after oral administration.

Niacin is indicated for type 2 diabetes due to its glucose-lowering effects.

Omega 3 fatty acids are essential fatty acids used for triglyceride lowering.

The most common side effects of omega 3 PUFAs include constipation, nausea, and flatulence.

Bleeding risk can be increased in individuals concomitantly taking anticoagulants or antiplatelets with omega 3 PUFAs.

Niacin is contraindicated in hepatic disease and should be used with caution with statins.