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Questions and Answers
What is the process by which excess cholesterol is eliminated from the body?
What is the process by which excess cholesterol is eliminated from the body?
- Conversion to urea for excretion
- Conversion to glucose for energy production
- Conversion to bile acids and bile salts (correct)
- Deposition in adipose tissue
What condition is indicated by excessive deposition of cholesterol under the skin and tendons?
What condition is indicated by excessive deposition of cholesterol under the skin and tendons?
- Arthritis
- Xanthomas (correct)
- Osteoporosis
- Dermatitis
What genetic disorder can cause hypercholesterolemia at a young age?
What genetic disorder can cause hypercholesterolemia at a young age?
- Hemochromatosis
- Cystic fibrosis
- Sickle cell anemia
- Familial hypercholesterolemia (correct)
Which enzyme may be insensitive to feedback regulation in individuals suffering from hypercholesterolemia due to genetic disorders?
Which enzyme may be insensitive to feedback regulation in individuals suffering from hypercholesterolemia due to genetic disorders?
What lifestyle choices are recommended to prevent hypercholesterolemia?
What lifestyle choices are recommended to prevent hypercholesterolemia?
If diet and exercise fail to reduce cholesterol levels, what may be recommended?
If diet and exercise fail to reduce cholesterol levels, what may be recommended?
What is the concentration range of plasma cholesterol in healthy individuals?
What is the concentration range of plasma cholesterol in healthy individuals?
Which fatty acid is usually attached to the OH group on C3 of the A ring in cholesterol esters?
Which fatty acid is usually attached to the OH group on C3 of the A ring in cholesterol esters?
What is the key source of dietary cholesterol?
What is the key source of dietary cholesterol?
Where does cholesterol synthesis primarily occur in the body?
Where does cholesterol synthesis primarily occur in the body?
What is the ratio of free circulating cholesterol to cholesterol esters in the blood?
What is the ratio of free circulating cholesterol to cholesterol esters in the blood?
How does cholesterol enter the circulation in the exogenous pathway?
How does cholesterol enter the circulation in the exogenous pathway?
Which form of cholesterol serves as the primary source of cholesterol for non-hepatic cells?
Which form of cholesterol serves as the primary source of cholesterol for non-hepatic cells?
How do humans primarily obtain cholesterol for non-de novo synthesis in tissues?
How do humans primarily obtain cholesterol for non-de novo synthesis in tissues?
Which process inactivates HMG-CoA reductase, a key enzyme in cholesterol synthesis?
Which process inactivates HMG-CoA reductase, a key enzyme in cholesterol synthesis?
What reducing equivalents provide carbon atoms for cholesterol synthesis?
What reducing equivalents provide carbon atoms for cholesterol synthesis?
Where does de novo synthesis of cholesterol predominantly occur in the human body?
Where does de novo synthesis of cholesterol predominantly occur in the human body?
Which lipoprotein is the main source of cholesterol for non-hepatic cells?
Which lipoprotein is the main source of cholesterol for non-hepatic cells?
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