Podcast
Questions and Answers
What is the process by which excess cholesterol is eliminated from the body?
What is the process by which excess cholesterol is eliminated from the body?
What condition is indicated by excessive deposition of cholesterol under the skin and tendons?
What condition is indicated by excessive deposition of cholesterol under the skin and tendons?
What genetic disorder can cause hypercholesterolemia at a young age?
What genetic disorder can cause hypercholesterolemia at a young age?
Which enzyme may be insensitive to feedback regulation in individuals suffering from hypercholesterolemia due to genetic disorders?
Which enzyme may be insensitive to feedback regulation in individuals suffering from hypercholesterolemia due to genetic disorders?
Signup and view all the answers
What lifestyle choices are recommended to prevent hypercholesterolemia?
What lifestyle choices are recommended to prevent hypercholesterolemia?
Signup and view all the answers
If diet and exercise fail to reduce cholesterol levels, what may be recommended?
If diet and exercise fail to reduce cholesterol levels, what may be recommended?
Signup and view all the answers
What is the concentration range of plasma cholesterol in healthy individuals?
What is the concentration range of plasma cholesterol in healthy individuals?
Signup and view all the answers
Which fatty acid is usually attached to the OH group on C3 of the A ring in cholesterol esters?
Which fatty acid is usually attached to the OH group on C3 of the A ring in cholesterol esters?
Signup and view all the answers
What is the key source of dietary cholesterol?
What is the key source of dietary cholesterol?
Signup and view all the answers
Where does cholesterol synthesis primarily occur in the body?
Where does cholesterol synthesis primarily occur in the body?
Signup and view all the answers
What is the ratio of free circulating cholesterol to cholesterol esters in the blood?
What is the ratio of free circulating cholesterol to cholesterol esters in the blood?
Signup and view all the answers
How does cholesterol enter the circulation in the exogenous pathway?
How does cholesterol enter the circulation in the exogenous pathway?
Signup and view all the answers
Which form of cholesterol serves as the primary source of cholesterol for non-hepatic cells?
Which form of cholesterol serves as the primary source of cholesterol for non-hepatic cells?
Signup and view all the answers
How do humans primarily obtain cholesterol for non-de novo synthesis in tissues?
How do humans primarily obtain cholesterol for non-de novo synthesis in tissues?
Signup and view all the answers
Which process inactivates HMG-CoA reductase, a key enzyme in cholesterol synthesis?
Which process inactivates HMG-CoA reductase, a key enzyme in cholesterol synthesis?
Signup and view all the answers
What reducing equivalents provide carbon atoms for cholesterol synthesis?
What reducing equivalents provide carbon atoms for cholesterol synthesis?
Signup and view all the answers
Where does de novo synthesis of cholesterol predominantly occur in the human body?
Where does de novo synthesis of cholesterol predominantly occur in the human body?
Signup and view all the answers
Which lipoprotein is the main source of cholesterol for non-hepatic cells?
Which lipoprotein is the main source of cholesterol for non-hepatic cells?
Signup and view all the answers
