Hyperadrenocorticism (Cushing's Syndrome) Pathophysiology
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Questions and Answers

What is the most common cause of Hyperadrenocorticism in dogs?

  • Adrenal cortical hyperplasia due to pituitary tumour
  • Iatrogenic Cushing's
  • Adrenal tumour (correct)
  • Cortisol deficiency

What is the effect of chronic cortisol production on the adrenal glands in Hyperadrenocorticism?

  • Adrenal gland necrosis
  • Adrenal gland calcification
  • Bilateral adrenal hyperplasia and hypertrophy (correct)
  • Unilateral adrenal atrophy

What is the characteristic laboratory finding in Hyperadrenocorticism?

  • Stress leukogram
  • Severe polycythaemia
  • Mild lymphocytosis
  • Mild polycythaemia (correct)

What is the purpose of the low-dose dexamethasone suppression test (LDDST) in Hyperadrenocorticism?

<p>To screen for Hyperadrenocorticism (C)</p> Signup and view all the answers

What is the gold standard diagnostic test for Hyperadrenocorticism?

<p>Endogenous ACTH measurement (C)</p> Signup and view all the answers

What is the effect of cortisol on the kidneys in Hyperadrenocorticism?

<p>Decreased ability to concentrate urine (A)</p> Signup and view all the answers

What is the characteristic clinical sign of Hyperadrenocorticism?

<p>Polyuria and polydipsia (C)</p> Signup and view all the answers

What is the result of a pituitary tumour on the adrenal glands in Hyperadrenocorticism?

<p>Bilateral adrenal hyperplasia (D)</p> Signup and view all the answers

What is the effect of long-term steroid use on the adrenal glands?

<p>Adrenal gland atrophy (D)</p> Signup and view all the answers

What is the purpose of the ACTH stimulation test in Hyperadrenocorticism?

<p>To evaluate the response of the adrenal glands to ACTH (B)</p> Signup and view all the answers

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