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Hyperadrenocorticism (Cushing's Syndrome) Pathophysiology

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Hyperadrenocorticism (Cushing's Syndrome) Pathophysiology

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Questions and Answers

What is the most common cause of Hyperadrenocorticism in dogs?

Adrenal cortical hyperplasia due to pituitary tumour

Iatrogenic Cushing's

Adrenal tumour (correct)

Cortisol deficiency

What is the effect of chronic cortisol production on the adrenal glands in Hyperadrenocorticism?

Adrenal gland necrosis

Adrenal gland calcification

Bilateral adrenal hyperplasia and hypertrophy (correct)

Unilateral adrenal atrophy

What is the characteristic laboratory finding in Hyperadrenocorticism?

Stress leukogram

Severe polycythaemia

Mild lymphocytosis

Mild polycythaemia (correct)

What is the purpose of the low-dose dexamethasone suppression test (LDDST) in Hyperadrenocorticism?

To screen for Hyperadrenocorticism Signup and view all the answers

What is the gold standard diagnostic test for Hyperadrenocorticism?

Endogenous ACTH measurement Signup and view all the answers

What is the effect of cortisol on the kidneys in Hyperadrenocorticism?

Decreased ability to concentrate urine Signup and view all the answers

What is the characteristic clinical sign of Hyperadrenocorticism?

Polyuria and polydipsia Signup and view all the answers

What is the result of a pituitary tumour on the adrenal glands in Hyperadrenocorticism?

Bilateral adrenal hyperplasia Signup and view all the answers

What is the effect of long-term steroid use on the adrenal glands?

Adrenal gland atrophy Signup and view all the answers

What is the purpose of the ACTH stimulation test in Hyperadrenocorticism?

To evaluate the response of the adrenal glands to ACTH Signup and view all the answers