Cushing's Syndrome Causes

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Questions and Answers

What is the primary goal of medications like ketoconazole, osilodrostat, mitotane, levoketoconazole, and metyrapone in treating Cushing syndrome?

  • To treat type 2 diabetes or high blood sugar
  • To lower the amount of ACTH from the tumor
  • To block the effect of cortisol on tissues
  • To control cortisol production at the adrenal gland (correct)

What is the mechanism of action of mifepristone in treating Cushing syndrome?

  • It lowers cortisol production at the adrenal gland
  • It replaces corticosteroids in the body
  • It increases the amount of ACTH from the tumor
  • It blocks the effect of cortisol on tissues (correct)

What is the primary function of pasireotide in treating Cushing syndrome?

  • To lower the amount of ACTH from the tumor (correct)
  • To lower cortisol production at the adrenal gland
  • To replace corticosteroids in the body
  • To block the effect of cortisol on tissues

What is the importance of monitoring 24-hour UFC and serum cortisol in patients with Cushing syndrome?

<p>To identify adrenal insufficiency (B)</p> Signup and view all the answers

What is the exception to monitoring steroid secretion in patients with Cushing syndrome?

<p>Mifepristone (A)</p> Signup and view all the answers

What is the primary goal of corticosteroid replacement therapy in patients with Cushing syndrome?

<p>To prevent adrenal insufficiency (B)</p> Signup and view all the answers

What is the name of the medication approved for people with Cushing syndrome who have type 2 diabetes or high blood sugar?

<p>Mifepristone (C)</p> Signup and view all the answers

What is the name of the medication given as a shot two times a day to lower cortisol levels in patients with Cushing syndrome?

<p>Pasireotide (C)</p> Signup and view all the answers

What is the term for the insufficient production of cortisol by the adrenal glands?

<p>Adrenal insufficiency (B)</p> Signup and view all the answers

What is the primary difference between primary and secondary adrenal insufficiency?

<p>The cause of cortisol deficiency (D)</p> Signup and view all the answers

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