Huntington's Disease Overview

What generally triggers the symptoms of Huntington's disease to appear?

Which of the following is a common physical effect of Huntington's disease?

What is the genetic mutation associated with Huntington's disease?

Which factor notably contributes to the risk of inheriting Huntington's disease?

What type of evaluation is used to diagnose Huntington's disease?

Huntington's Disease

Incurable, hereditary brain disorder
Characterized by degeneration of brain cells
Affects motor functions, thinking ability, and behavior
Impacts approximately 1 in 10,000 people
Symptoms typically appear between ages 30-40, but can sometimes remain dormant longer
Affects males and females equally
Genetic mutation (CAG) over-production in the genetic sequence.
A 50/50 chance of inheriting the HD gene from one parent.

Physical Effects

Movement: Jerky, uncontrolled movements, slow eye movements, difficulty with speech and swallowing, cognitive issues, repetitive thoughts, focusing issues.

Psychiatric Effects

Mental Health: Depression, aggression, anxiety, sadness, and increased suicide/alcoholism risk.

Cognitive Effects

Difficulty with information processing
Organization problems
Disorientation
Problems with concentration and memory

Diagnosis and Treatment

Diagnosis: Physical and psychological evaluations to determine symptom onset. Rating scales assess motor and cognitive/behavioral function.
Treatment: Currently incurable, but some medications can help lessen symptoms.

Explore the complexities of Huntington's Disease, an incurable hereditary condition that profoundly impacts motor functions and mental health. This quiz covers the symptoms, genetic causes, and effects on cognition and behavior, as well as diagnostic approaches. Understand the challenges faced by individuals affected by this disorder.