10 Questions
Which pathway is lost first in Huntington's Disease leading to an increased UMN excitability?
Striatopallidal
What is the characteristic movement disorder seen in Huntington's Disease?
Chorea
What type of inheritance pattern is observed in Huntington's Disease?
Autosomal dominant
Which region undergoes structural loss in Huntington's Disease, leading to enlargement of the lateral ventricle?
Putamen
What mutation leads to Huntington's Disease, characterized by the expansion of which triplet within the coding region of the huntingtin gene?
CAG
What is the main cause of neuronal loss in Huntington's disease?
Mutated huntingtin protein expression
Which type of neurons are spared in Huntington's disease?
ACh neurons
What treatment can be used to alleviate symptoms of Huntington's disease?
Tetrabenazine
Which chromosome experiences a genetic mutation in Huntington's disease?
4th chromosome
What specific order does neuronal loss follow in Huntington's disease?
Corticostriatal → striatopallidal → striatonigral
Learn about Huntington’s disease, a progressive and fatal neurological disorder characterized by the loss of specific brain regions. Understand the pathway of neuronal loss and its impact on motor functions.
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
