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Questions and Answers
Which pathway is lost first in Huntington's Disease leading to an increased UMN excitability?
Which pathway is lost first in Huntington's Disease leading to an increased UMN excitability?
- Striatopallidal (correct)
- Corticostriatal
- Striatonigral
- Thalamocortical
What is the characteristic movement disorder seen in Huntington's Disease?
What is the characteristic movement disorder seen in Huntington's Disease?
- Tremor
- Dystonia
- Bradykinesia
- Chorea (correct)
What type of inheritance pattern is observed in Huntington's Disease?
What type of inheritance pattern is observed in Huntington's Disease?
- Y-linked dominant
- Autosomal recessive
- X-linked recessive
- Autosomal dominant (correct)
Which region undergoes structural loss in Huntington's Disease, leading to enlargement of the lateral ventricle?
Which region undergoes structural loss in Huntington's Disease, leading to enlargement of the lateral ventricle?
What mutation leads to Huntington's Disease, characterized by the expansion of which triplet within the coding region of the huntingtin gene?
What mutation leads to Huntington's Disease, characterized by the expansion of which triplet within the coding region of the huntingtin gene?
What is the main cause of neuronal loss in Huntington's disease?
What is the main cause of neuronal loss in Huntington's disease?
Which type of neurons are spared in Huntington's disease?
Which type of neurons are spared in Huntington's disease?
What treatment can be used to alleviate symptoms of Huntington's disease?
What treatment can be used to alleviate symptoms of Huntington's disease?
Which chromosome experiences a genetic mutation in Huntington's disease?
Which chromosome experiences a genetic mutation in Huntington's disease?
What specific order does neuronal loss follow in Huntington's disease?
What specific order does neuronal loss follow in Huntington's disease?
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