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Questions and Answers
Microbes are coated by C4 and C3d.
False
B cells recognize microbes through BCRs and C3d via CR2.
True
B cells do not have Toll-like receptors (TLRs).
False
Activated B cells enter cell cycle and proliferate, synthesizing more IgG and free IgG.
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Soluble protein antigens can cross-link and activate B cells strongly.
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Activated B cells move out of follicles and towards a compartment where Helper T-cells are absent.
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Macrophages in subcapsular sinus can transfer antigens to B-cells in lymph nodes.
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Antigen-induced clustering of membrane Ig receptors triggers mechanical signals.
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IgM and IgD receptors have conserved immunoreceptor tyrosine-based activation motifs (ITAMS).
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Tyrosines in ITAMS are phosphorylated by SyK tyrosine kinase.
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The complement system provides signals for the inhibition of B lymphocytes.
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B-cell receptor complex is formed by IgA and IgB along with other receptors.
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