Human Tissue Types Overview
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Questions and Answers

What is the primary function of muscle tissue?

  • Contraction to produce movement (correct)
  • Protection of organs
  • Storing energy
  • Transporting nutrients

Connective tissue and epithelial tissue are two of the four major types of tissues in the human body.

True (A)

What are the three types of specialized contractile cells in muscle tissue?

Skeletal muscle, cardiac muscle, smooth muscle

Blood tissue has a __________ matrix.

<p>liquid</p> Signup and view all the answers

Match the following types of tissues with their descriptions:

<p>Muscle tissue = Specialized for contraction Nervous tissue = Transmits impulses for communication Epithelial tissue = Covers body surfaces and lines cavities Connective tissue = Supports and binds other tissues</p> Signup and view all the answers

Which type of muscle tissue is described as striated on microscopic examination?

<p>Skeletal muscle (A)</p> Signup and view all the answers

The matrix of tissues is always living.

<p>False (B)</p> Signup and view all the answers

How do the four major types of tissues interact in the body?

<p>They interweave to form the fabric of the body.</p> Signup and view all the answers

What percentage of an adult male's body weight is made up of water?

<p>60% (C)</p> Signup and view all the answers

The intra-cellular fluid accounts for approximately one-third of the body’s water content.

<p>False (B)</p> Signup and view all the answers

What mechanism maintains the stability of the internal environment in the body?

<p>Homeostasis</p> Signup and view all the answers

Water in the body can be divided into intra-cellular and __________ compartments.

<p>extra-cellular</p> Signup and view all the answers

Match the following components of body fluids with their descriptions:

<p>Intra-cellular Fluid = Fluid within cells Extra-cellular Fluid = Fluid outside the cells Interstitial Fluid = Fluid found between cells Plasma = Fluid component of blood</p> Signup and view all the answers

Which organ system is primarily responsible for transporting nutrients, cells, and waste throughout the body?

<p>Circulatory System (B)</p> Signup and view all the answers

Positive feedback mechanisms are responsible for stabilizing the internal environment.

<p>False (B)</p> Signup and view all the answers

What is the role of the extra-cellular fluid in the body?

<p>Provides a constant environment for cells and transports substances.</p> Signup and view all the answers

Which of the following factors are considered physical factors necessary for homeostasis?

<p>Temperature and pH (A)</p> Signup and view all the answers

The control center of homeostasis is found in the muscle tissues.

<p>False (B)</p> Signup and view all the answers

What is the role of effectors in the homeostatic system?

<p>To bring about the appropriate response to restore optimum conditions.</p> Signup and view all the answers

The optimal temperature for human body homeostasis is approximately _____ degrees Celsius.

<p>36.9</p> Signup and view all the answers

Match the components of a homeostatic system to their functions:

<p>Detector = Monitors changes in the environment Control Centre = Analyzes data and sends signals Effector = Carries out the response to restore balance Set Point = The optimal level for a condition</p> Signup and view all the answers

What is the primary mechanism through which the body responds to changes in homeostasis?

<p>Negative feedback system (B)</p> Signup and view all the answers

Thermoregulation involves only the brain's control center.

<p>False (B)</p> Signup and view all the answers

Name two chemical factors that are important for homeostasis.

<p>Oxygen and nutrients.</p> Signup and view all the answers

Which function of the skeletal system involves the production of blood cells?

<p>Blood cell formation (C)</p> Signup and view all the answers

Cartilage provides rigid support to bones.

<p>False (B)</p> Signup and view all the answers

Name one type of cell produced by the red bone marrow.

<p>Red blood cells</p> Signup and view all the answers

Bones store _______ in their matrix.

<p>calcium</p> Signup and view all the answers

Match the following types of bones with their functions:

<p>Long bones = Function as levers Short bones = Provide stability and support Flat bones = Protect internal organs Irregular bones = Complex shapes and functions</p> Signup and view all the answers

What type of bone acts as a cushion between other bones?

<p>Cartilage (B)</p> Signup and view all the answers

The skeletal system has no role in attachment for muscles.

<p>False (B)</p> Signup and view all the answers

What is the primary composition of the bone matrix?

<p>Calcium and phosphorus</p> Signup and view all the answers

What is the role of osteoblasts in bone remodeling?

<p>Formation of new bone (C)</p> Signup and view all the answers

Osteoporosis occurs when bone formation is faster than bone resorption.

<p>False (B)</p> Signup and view all the answers

Which demographic groups are most commonly affected by osteoporosis?

<p>The elderly and postmenopausal women</p> Signup and view all the answers

Osteocytes are mature bone cells that maintain the health of ______.

<p>bone</p> Signup and view all the answers

Match the following bone cells with their functions:

<p>Osteoblasts = Formation of new bone Osteoclasts = Resorption and removal of bone Osteocytes = Maintenance of bone health</p> Signup and view all the answers

What contributes to bone remodeling?

<p>Hormonal action and mechanical stress (B)</p> Signup and view all the answers

What is the role of acetylcholine in muscle contraction?

<p>It binds to receptors in the sarcolemma. (D)</p> Signup and view all the answers

A continuous balance between osteoblast and osteoclast activities is essential for maintaining normal bone structure.

<p>True (A)</p> Signup and view all the answers

What hormonal changes affect the activity of osteoclasts and osteoblasts?

<p>Menopause-related hormonal changes</p> Signup and view all the answers

Calcium ions bind to tropomyosin to expose myosin-binding sites on actin.

<p>False (B)</p> Signup and view all the answers

What is the function of the sarcoplasmic reticulum in muscle contraction?

<p>It releases calcium ions into the cytoplasm of muscle cells.</p> Signup and view all the answers

Myosin heads on thick filaments pull the __________ filament toward the center of the sarcomere during contraction.

<p>actin</p> Signup and view all the answers

Match the following steps with their corresponding events in muscle contraction:

<ol> <li>Acetylcholine release = A. Binds to receptors in the sarcolemma</li> <li>Calcium ion release = B. Exposes myosin-binding sites</li> <li>Myosin-actin binding = C. Generates power stroke</li> <li>ATP hydrolysis = D. Resets myosin head</li> </ol> Signup and view all the answers

What effect does the neurotoxin from Clostridium tetani have on muscle function?

<p>It prevents inhibition of nervous impulse activity. (A)</p> Signup and view all the answers

Tetanus can be effectively prevented through proper vaccination.

<p>True (A)</p> Signup and view all the answers

What happens to myosin when it binds with ATP?

<p>It dissociates from actin.</p> Signup and view all the answers

Which type of neuron carries signals from the body to the central nervous system?

<p>Sensory neuron (B)</p> Signup and view all the answers

Interneurons are responsible for carrying signals from the brain to the muscles.

<p>False (B)</p> Signup and view all the answers

What is the primary role of neuroglia in the nervous system?

<p>Support, nourish, and protect neurons</p> Signup and view all the answers

Motor neurons also known as __________ carry impulses away from the spinal cord to muscles and glands.

<p>efferent neurons</p> Signup and view all the answers

Match each type of neuron with its function:

<p>Sensory neuron = Carries signals to the CNS Motor neuron = Carries signals away from the CNS Interneuron = Connects neurons within the CNS Neuroglia = Supports and protects neurons</p> Signup and view all the answers

What is the primary function of the cerebral cortex?

<p>Sensory perception (A)</p> Signup and view all the answers

White matter in the spinal cord consists of gray matter and facilitates communication between the brain and spinal cord.

<p>False (B)</p> Signup and view all the answers

What type of reflex is demonstrated by the knee jerk reflex?

<p>Patellar reflex</p> Signup and view all the answers

The brain's _______ helps in regulating sleep and wake cycles.

<p>cerebral cortex</p> Signup and view all the answers

Match the following components of the spinal cord with their functions:

<p>Gray matter = Receives and processes sensory information White matter = Carries information from the brain to the spinal cord Dorsal root nerves = Bring stimuli to the spinal cord Ventral root nerves = Control somatic and visceral effectors</p> Signup and view all the answers

Which part of the cerebral cortex is primarily responsible for motor functions?

<p>Frontal lobe (B)</p> Signup and view all the answers

Convolutions in the cerebrum help in increasing the surface area for neural connections.

<p>True (A)</p> Signup and view all the answers

What is the role of the basal ganglia in the brain?

<p>Produces automatic movement and postures</p> Signup and view all the answers

Which hormone is primarily responsible for stimulating uterine contractions during childbirth?

<p>Oxytocin (D)</p> Signup and view all the answers

The posterior pituitary gland secretes hormones directly into the bloodstream without the involvement of the hypothalamus.

<p>False (B)</p> Signup and view all the answers

What is the main function of Antidiuretic Hormone (ADH)?

<p>Causes kidneys to reabsorb more water, reducing urine output.</p> Signup and view all the answers

The anterior pituitary gland is also known as the __________.

<p>adenohypophysis</p> Signup and view all the answers

Match the following anterior pituitary hormones with their actions:

<p>Growth Hormone = Stimulates growth and metabolism Prolactin = Stimulates milk production FSH = Stimulates production of ova and sperm ACTH = Stimulates the adrenal cortex to secrete glucocorticoids</p> Signup and view all the answers

Which type of brainwave is associated with deep sleep?

<p>Delta waves (D)</p> Signup and view all the answers

Alpha waves are associated with excitement and high stress levels.

<p>False (B)</p> Signup and view all the answers

What neurotransmitter is deficient in Parkinson's disease?

<p>Dopamine</p> Signup and view all the answers

The waveforms in the EEG are generated by impulses near the communication between neurons and __________.

<p>nerves</p> Signup and view all the answers

Match the following brainwave types with their associated states:

<p>Alpha waves = Wakefulness, relaxed Beta waves = Excitement, concentration Theta waves = Transiently during sleep Delta waves = Deep sleep</p> Signup and view all the answers

What is one of the uses of an electroencephalograph (EEG)?

<p>To monitor effects of exercise (C)</p> Signup and view all the answers

Theta waves are most commonly observed in adults undergoing normal sleep.

<p>False (B)</p> Signup and view all the answers

What symptoms are commonly associated with Parkinson's disease?

<p>Tremors, rigidity, unstable posture</p> Signup and view all the answers

What is primarily responsible for the enlargement of the thyroid gland in cases of iodine deficiency?

<p>Increased TSH secretion (B)</p> Signup and view all the answers

Calcitonin and parathyroid hormone (PTH) have the same effect on blood calcium levels.

<p>False (B)</p> Signup and view all the answers

What is the primary goal of the sympathetic division of the nervous system?

<p>To help the body cope with threats (C)</p> Signup and view all the answers

What hormone is released from the parathyroid glands and increases blood calcium levels?

<p>parathyroid hormone (PTH)</p> Signup and view all the answers

The parasympathetic system is primarily active during stressful situations.

<p>False (B)</p> Signup and view all the answers

Iodine is required for the production of ___________ hormone.

<p>thyroid</p> Signup and view all the answers

Match the following hormones with their effects on blood calcium levels:

<p>Calcitonin = Lowers blood calcium levels Parathyroid hormone (PTH) = Raises blood calcium levels</p> Signup and view all the answers

What physiological responses occur when the sympathetic system is activated?

<p>Increased heart rate, rapid breathing, dilated pupils, and increased blood flow to muscles.</p> Signup and view all the answers

An _______ is used to measure the electrical activity of the brain.

<p>electroencephalogram (EEG)</p> Signup and view all the answers

Match the following functions to the appropriate division of the nervous system:

<p>Sympathetic = Increase heart rate and respiration Parasympathetic = Promote digestion and energy conservation</p> Signup and view all the answers

Which of the following is NOT a function of the parasympathetic system?

<p>Increases metabolism (A)</p> Signup and view all the answers

An EEG can be used to monitor brain activity during general anesthesia.

<p>True (A)</p> Signup and view all the answers

List two situations in which an EEG would be used.

<p>To diagnose epilepsy and to evaluate cognitive impairment.</p> Signup and view all the answers

What is the primary function of sensory neurons?

<p>To carry signals from the outer body parts into the central nervous system (D)</p> Signup and view all the answers

Motor neurons are responsible for transmitting signals from the spinal cord and brain to the muscles and glands.

<p>True (A)</p> Signup and view all the answers

What are neuroglia and what role do they play in the nervous system?

<p>Neuroglia are supporting cells in the nervous system that nourish and protect neurons.</p> Signup and view all the answers

Interneurons connect various neurons within the __________ and spinal cord.

<p>brain</p> Signup and view all the answers

Match the types of neurons with their descriptions:

<p>Sensory neuron = Carries signals to the central nervous system Motor neuron = Carries signals from the central nervous system Interneuron = Connects neurons within the brain and spinal cord Neuroglia = Supports and protects neurons</p> Signup and view all the answers

What is the function of the Node of Ranvier?

<p>To facilitate faster transmission of electrical impulses (C)</p> Signup and view all the answers

Schwann cells are found in the central nervous system.

<p>False (B)</p> Signup and view all the answers

What are the main functions of Schwann cells?

<p>To form a sheath around peripheral axons and assist in the regeneration of cut or injured axons.</p> Signup and view all the answers

Most sensory neurons of the peripheral nervous system are classified as __________ neurons.

<p>unipolar</p> Signup and view all the answers

Match the types of neurons to their characteristics:

<p>Anaxonic = No distinction between dendrites and axon; found in the brain Bipolar = Two distinct processes; involved in special senses Multipolar = Most common type in CNS; multiple dendrites Unipolar = Continuous dendrite and axon; cell body to one side</p> Signup and view all the answers

Which type of neuron has a single axon and a single dendrite?

<p>Bipolar (C)</p> Signup and view all the answers

All neurons have more than one axon.

<p>False (B)</p> Signup and view all the answers

What role do axon terminals play in neuron communication?

<p>They send signals to the dendrites of another neuron.</p> Signup and view all the answers

Which of the following is NOT a function of the nervous system?

<p>Respiration function (C)</p> Signup and view all the answers

The autonomic nervous system is responsible for voluntary muscle control.

<p>False (B)</p> Signup and view all the answers

What is the role of a neurotransmitter?

<p>To pass the impulse from one neuron to another.</p> Signup and view all the answers

The __________ potential indicates the resting state of a nerve cell.

<p>resting</p> Signup and view all the answers

Match the following terms with their definitions:

<p>Action potential = A propagated change in membrane potential Depolarization = Change in potential towards 0 mv Repolarization = Return of membrane potential to resting state Synapse = Site of communication between neurons</p> Signup and view all the answers

Which of the following best describes a neuromodulator?

<p>Adjusts the sensitivity of a neuron to neurotransmitters (C)</p> Signup and view all the answers

Name two functions of the central nervous system.

<p>Processing information and controlling responses.</p> Signup and view all the answers

Neurotransmitters are only released at the synapse.

<p>True (A)</p> Signup and view all the answers

What is the resting membrane potential of a neuron at rest?

<p>-70 (D)</p> Signup and view all the answers

Depolarization occurs when Na+ channels close and K+ ions flood into the neuron.

<p>False (B)</p> Signup and view all the answers

What happens during repolarization of a neuron?

<p>K+ ions flood out of the cell and Na+ channels close.</p> Signup and view all the answers

The process of restoring the resting potential of a neuron is called __________.

<p>repolarization</p> Signup and view all the answers

Match the stages of the action potential process with their descriptions:

<p>Depolarization = Na+ channels open, flooding Na+ into the neuron Repolarization = K+ channels open, allowing K+ to exit Hyperpolarization = Membrane potential temporarily exceeds resting potential</p> Signup and view all the answers

Which ion primarily causes the neuron membrane to depolarize?

<p>Na+ (C)</p> Signup and view all the answers

Hyperpolarization occurs when too many K+ ions flow back into the cell.

<p>False (B)</p> Signup and view all the answers

What mechanism helps restore the membrane potential after an action potential?

<p>Na+/K+ ATPase pump</p> Signup and view all the answers

What is hyperpolarization in a neuron?

<p>A change that makes the membrane potential more negative (A)</p> Signup and view all the answers

The resting membrane potential of a neuron is approximately 70 mV more positive inside than outside.

<p>False (B)</p> Signup and view all the answers

What triggers an action potential in a neuron?

<p>A stimulus that depolarizes the membrane beyond the threshold level.</p> Signup and view all the answers

The sequence of events that occurs when a neuron sends a signal is called the __________.

<p>action potential</p> Signup and view all the answers

Which of the following correctly describes the all-or-nothing rule in neurons?

<p>If the threshold is reached, action potential fires at a fixed size (C)</p> Signup and view all the answers

Match neurotransmitters with their functions:

<p>Acetylcholine = Muscle contraction Dopamine = Reward and pleasure Serotonin = Mood regulation Norepinephrine = Fight or flight response</p> Signup and view all the answers

At rest, there are relatively more __________ ions outside the neuron and more __________ ions inside.

<p>sodium, potassium</p> Signup and view all the answers

A synapse is where two neurons meet to communicate with each other.

<p>True (A)</p> Signup and view all the answers

What is the primary cause of goiter?

<p>Iodine deficiency (C)</p> Signup and view all the answers

Calcitonin raises calcium levels in the blood.

<p>False (B)</p> Signup and view all the answers

What hormone increases the levels of calcium in the blood?

<p>Parathyroid hormone (PTH)</p> Signup and view all the answers

The thyroid gland releases hormones required for producing __________.

<p>thyroid hormone</p> Signup and view all the answers

Match the following glands with their functions:

<p>Thyroid Gland = Produces calcitonin and thyroid hormones Parathyroid Glands = Produce parathyroid hormone (PTH) Pituitary Gland = Regulates TSH secretion Adrenal Gland = Produces cortisol and adrenaline</p> Signup and view all the answers

Flashcards

Homeostasis

The mechanism that keeps the body's internal environment stable and nearly constant, allowing cellular functions to work efficiently.

Total Body Water

Water accounts for 60% of an adult male's and 50% of a females' body weight.

Intracellular Fluid

The fluid inside cells, making up about two-thirds of total body water.

Extracellular Fluid

The fluid outside cells, consisting of interstitial fluid, plasma, lymph, and other fluids.

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Interstitial Fluid

The fluid that fills the spaces between cells.

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Major Organ Systems

Groups of organs that work together to perform specific functions.

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Integumentary System

Organ system that forms a protective outer layer to the body. (skin, hair, nails).

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Skeletal System

Organ system that provides support and structure to the body.

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Tissues

Groups of similar cells working together with a non-living matrix, which secretes a substance that varies in composition based on tissue type (liquid, semi-solid, solid).

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Muscle Tissue

A tissue specialized for contraction, causing movement of body parts and the body itself. Needs a good blood supply for oxygen, calcium, nutrients, and waste removal.

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Skeletal Muscle

Muscle tissue attached to bones that causes skeletal movement.

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Cardiac Muscle

Muscle tissue that forms the heart and pumps blood.

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Smooth Muscle

Muscle tissue found in the internal organs that controls involuntary movements.

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Striated Muscle

Muscle tissue with visible stripes under a microscope.

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Four major tissue types

Muscle, nervous, epithelial, and connective tissues.

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Blood tissue

A type of tissue with a liquid matrix.

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Set Point

The optimal level for a controlled variable, like body temperature.

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Detector/Receptor

Monitors internal and external conditions, sending signals about changes.

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Control Center

In the brain, assesses signals and directs the appropriate response.

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Effector

Acts to restore the optimal level (e.g., sweat glands or muscles).

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Negative Feedback

A system that counteracts a change, returning conditions to the set point.

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Thermoregulation

Control of body temperature.

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Components of a Homeostatic System

Detector (sensor), Control Center, and Effector work together for homeostasis.

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Hematopoiesis

The process of blood cell production (red and white blood cells and platelets) in bone marrow.

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Bone Functions

Bones support soft tissues, protect internal organs (like the brain and heart), provide attachment points for muscles, store calcium, and create blood cells.

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Bone Mineral Storage

Bones store calcium and phosphorus, which can be released if needed by other body systems.

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Cartilage Function

Cartilage plays a role in bone growth, acts as a cushion between bones, and provides flexible support.

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Tendons

Tendons connect muscles to bones.

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Ligaments

Ligaments connect bones to bones.

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Long Bones

Long bones function as levers in the body, enabling movement.

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Types of Bones

Bones are shaped to fit their functions (e.g., long bones for movement), including long, short, flat, irregular and sesamoid bones.

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Osteocyte

A mature bone cell responsible for maintaining the health of bone tissue.

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Osteoclast

A bone cell that breaks down and removes old bone tissue, helping to shape and remodel bones.

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Bone Remodeling

A continuous process where bone cells constantly rebuild and reshape bone tissue.

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Osteoporosis

A condition where bone breakdown (resorption) exceeds bone formation, leading to weakened bones and increased fracture risk.

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Who's at risk for osteoporosis?

Elderly individuals and postmenopausal women are at increased risk due to hormonal changes and slower bone formation.

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How does osteoporosis occur?

Hormonal changes, especially during menopause, can disrupt the balance between bone formation and breakdown, leading to a net loss of bone mass.

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What's the role of mechanical stress in bone remodeling?

Weight-bearing exercises apply mechanical stress to bones, stimulating bone formation and strengthening them.

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How does calcium regulation affect bone remodeling?

Hormones like parathyroid hormone and calcitonin control calcium levels in the blood, indirectly influencing bone formation and resorption.

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What is the role of Acetylcholine (ACh) at the neuromuscular junction?

Acetylcholine is a neurotransmitter released by motor neurons that binds to receptors on the sarcolemma of muscle fibers, triggering a cascade of events leading to muscle contraction.

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What is the role of the T-tubules in muscle contraction?

T-tubules are invaginations of the sarcolemma that carry the action potential from the surface of the muscle fiber deep into the cell, reaching the sarcoplasmic reticulum.

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What is the role of the sarcoplasmic reticulum in muscle contraction?

The sarcoplasmic reticulum is a specialized organelle that stores calcium ions. When the action potential reaches the sarcoplasmic reticulum, it releases calcium ions into the cytoplasm.

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How does calcium activate muscle contraction?

Calcium ions bind to troponin, causing a conformational change that shifts tropomyosin off the myosin binding sites on actin. This exposes the myosin binding sites, allowing myosin heads to attach and initiate the power stroke.

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Power Stroke

The power stroke is the sliding of the thin filament (actin) along the thick filament (myosin), shortening the sarcomere and ultimately leading to muscle contraction. This movement is driven by the myosin head 'walking' along the actin filament, pulling it towards the center of the sarcomere.

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How does ATP facilitate muscle relaxation?

ATP binding to the myosin head causes the myosin head to detach from actin. This is essential for muscle relaxation, as it breaks the link between the filaments and allows them to slide back to their resting positions.

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What happens during tetanus infection?

The bacteria Clostridium tetani releases a neurotoxin that blocks the release of inhibitory neurotransmitters in the nervous system. This prevents the normal relaxation of muscles, resulting in prolonged muscle contractions.

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How does tetanus affect muscular function?

Tetanus prevents calcium reabsorption by the sarcoplasmic reticulum, leading to sustained muscle contraction. This can cause symptoms like lockjaw, progressing to rigidity throughout the body.

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Sensory Neuron

A neuron that carries signals from the outer parts of your body (like skin, senses) to the central nervous system (brain and spinal cord).

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Motor Neuron

A neuron that carries signals from the central nervous system (brain and spinal cord) to the muscles, skin, and glands, causing actions.

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Interneuron

A neuron that connects other neurons within the brain and spinal cord, acting as a relay for signals.

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What is the function of Neuroglia?

Neuroglia, also called glial cells, are supporting cells in the nervous system. They don't transmit signals like neurons, but they nourish, protect, and support neurons.

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Why are glial cells important?

Glial cells are essential for the proper function of the nervous system. They provide support, nourishment, and protection to neurons, creating an environment where they can thrive.

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Pain Relief Mechanism

Pain relief often works by stopping the release of neurotransmitters at synapses that carry pain signals.

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Sympathetic Nervous System

The 'fight or flight' system, active during stress or threat, prepares the body for action by increasing heart rate, breathing, and blood flow to muscles.

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Parasympathetic Nervous System

The 'rest and digest' system, active when the body is at rest, promotes digestion, conserves energy, and slows down bodily functions.

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Electroencephalogram (EEG)

A test that measures brain electrical activity using electrodes placed on the scalp, used to diagnose epilepsy, stroke, and other brain conditions.

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EEG Applications

EEGs are used for diagnosing a variety of conditions like epilepsy, stroke, brain tumors, and sleep disorders.

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EEG for Consciousness

EEGs can help assess impaired consciousness, altered mental states, and cognitive impairment.

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EEG for Sleep Disorders

EEGs are used to diagnose sleep disorders like narcolepsy by analyzing brainwave patterns during sleep.

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EEG under Anesthesia

EEGs monitor brain activity during general anesthesia, ensuring the patient's brain remains safe.

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Cerebrum

The largest part of the brain, responsible for higher-level functions like thinking, language, and movement.

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Cerebral Cortex

The thin outer layer of gray matter that covers the cerebrum, responsible for conscious thought, sensory perception, and motor control.

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Sulci and Fissures

Grooves and deep folds in the cerebrum, respectively, that increase its surface area and help divide it into lobes.

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Basal Ganglia

Clusters of gray matter located deep within the cerebrum, important for smooth, coordinated movements and posture.

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Gray Matter in Spinal Cord

Located in the center of the spinal cord, contains sensory and motor nuclei responsible for receiving and transmitting information.

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White Matter in Spinal Cord

Surrounding the gray matter, contains nerve fibers that carry information between the brain and spinal cord and within the spinal cord.

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Dorsal Root Nerves

Nerves entering the spinal cord that carry sensory information from the body to the brain.

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Ventral Root Nerves

Nerves exiting the spinal cord that carry motor commands from the brain to muscles and glands.

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EEG

Electroencephalogram - a test that measures the electrical activity in the brain using electrodes placed on the scalp.

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Brainwaves

Different types of brainwave patterns associated with various states of arousal, like wakefulness, sleep, and stress.

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Alpha Waves

Brainwaves associated with a relaxed, wakeful state. Often seen when you're resting with closed eyes.

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Beta Waves

Brainwaves associated with alertness, concentration, and stress. Usually seen when you're focused on tasks or feeling anxious.

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Theta Waves

Brainwaves typically seen in children and adults during light sleep or when frustrated. Can also indicate potential brain issues.

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Delta Waves

Slow, low-frequency brainwaves associated with deep sleep. They're the strongest brainwaves in the deepest sleep stages.

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Dopamine

A neurotransmitter that plays a key role in movement, mood, and reward. Its deficiency in Parkinson's disease causes tremors and movement problems.

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Parkinson's Disease

A progressive nervous system disorder that affects movement. Caused by the death of dopamine-producing cells in the brain.

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Hypothyroidism

Condition where the thyroid gland is underactive, producing insufficient thyroid hormone (T4).

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Goiter

Abnormal enlargement of the thyroid gland that can be caused by either underactive (hypothyroid) or overactive (hyperthyroid) thyroid.

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Calcitonin's effect on calcium

Calcitonin, a hormone released by the thyroid gland, helps lower blood calcium levels by stimulating calcium deposition into bones.

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Parathyroid Hormone (PTH)

Hormone produced by the parathyroid glands that increases blood calcium levels by promoting calcium reabsorption in the kidneys, reducing calcium excretion, and increasing calcium release from bones.

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Calcitonin and PTH's Relationship

Calcitonin and PTH have opposite effects on blood calcium levels. Calcitonin lowers it, while PTH raises it. This antagonistic relationship maintains calcium balance in the body.

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Anterior Pituitary Gland

The anterior pituitary gland, also known as the adenohypophysis, is a major endocrine gland in the brain. It's responsible for producing and releasing various hormones that regulate several physiological functions, such as growth, reproduction, lactation, and stress response.

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How is the Anterior Pituitary Regulated?

The anterior pituitary gland is regulated through a complex system of blood vessels connected to the hypothalamus. The hypothalamus secretes releasing hormones that travel to the anterior pituitary, triggering the release of specific hormones.

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Posterior Pituitary Gland

The posterior pituitary gland, also known as the neurohypophysis, is another important part of the pituitary gland. It doesn't produce hormones but stores and releases hormones produced by the hypothalamus.

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What hormones does the posterior pituitary release?

The posterior pituitary gland releases two main hormones: oxytocin, which stimulates uterine contractions and milk production, and antidiuretic hormone (ADH), also known as vasopressin, which controls water reabsorption in the kidneys.

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What's the difference between anterior and posterior pituitary glands?

The main difference between the anterior and posterior pituitary gland lies in their regulation. The anterior pituitary is controlled by the hypothalamus through blood vessels, whereas the posterior pituitary receives direct signals from the hypothalamus through nerves.

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What are Neuroglia?

Neuroglia, also called glial cells, are supporting cells in the nervous system. They don't transmit signals like neurons, but they nourish, protect, and support neurons.

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Node of Ranvier

The unmyelinated gaps along an axon that allow faster transmission of electrical impulses by speeding up the signal.

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Schwann Cell

A type of glial cell found in the peripheral nervous system (PNS) that wraps around axons, forming a myelin sheath to protect and insulate them.

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Axon Terminal

The end of an axon where neurotransmitters are released to communicate with other neurons or target cells.

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Anaxonic Neuron

A type of neuron without a clear distinction between axon and dendrites, making it difficult to identify.

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Bipolar Neuron

A neuron with two distinct processes - one dendrite and one axon, with the cell body in between.

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Unipolar Neuron

A neuron where the axon and dendrite are fused, with the cell body off to the side.

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Multipolar Neuron

A neuron with many dendrites and a single axon, the most common type in the central nervous system (CNS).

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Types of Neurons by Structure

Neurons are categorized based on the arrangement of their dendrites, cell body, and axon.

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Neurotransmitter

A chemical messenger released by a neuron to communicate with another neuron or a target cell.

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Neuromodulator

A chemical that fine-tunes the response of a neuron to a neurotransmitter, making it more or less sensitive.

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Synapse

The junction or gap between a neuron and another cell where communication occurs.

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Resting Potential

The electrical charge difference across the membrane of a neuron when it's not actively transmitting signals.

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Action Potential

A brief electrical signal that travels down the axon of a neuron, initiated by a stimulus and causing the release of neurotransmitters.

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Depolarization

The change in membrane potential where the inside of the neuron becomes more positive, making it more likely to fire an action potential.

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Repolarization

The return of the membrane potential to its resting state, after depolarization, by restoring the original balance of ions inside and outside the neuron.

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What is the role of the Central Nervous System?

The CNS, consisting of the brain and spinal cord, acts as the control center, receiving and processing sensory information and sending out motor commands to the body.

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Hyperpolarization

A temporary state where a neuron's membrane potential becomes even more negative than its resting potential, usually caused by a prolonged outflow of potassium (K+) ions.

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Sodium-Potassium Pump

A protein pump that actively transports sodium ions (Na+) out of the neuron and potassium ions (K+) into the neuron, requiring energy to maintain the resting membrane potential.

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What do graded potentials do?

Graded potentials are localized changes in membrane potential that can either depolarize or hyperpolarize the neuron, and their strength is proportional to the stimulus that caused them.

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What makes action potentials different from graded potentials?

Action potentials are all-or-nothing events that occur when the membrane potential reaches a threshold level, whereas graded potentials can vary in strength and do not necessarily trigger an action potential.

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Thyroid Hormone Production

The thyroid gland requires iodine to produce thyroid hormone (T4).

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Goiter: Enlarged Thyroid

Goiter is an abnormal enlargement of the thyroid gland. It can be caused by either hypothyroidism (underactive) or hyperthyroidism (overactive).

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Calcitonin's Role

Calcitonin, a hormone released by the thyroid gland, helps lower blood calcium levels by stimulating calcium deposition into bones.

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Calcitonin and PTH: Opposite Effects

Calcitonin and PTH have opposite effects on blood calcium levels. Calcitonin lowers it, while PTH raises it. This opposing action helps maintain calcium balance in the body.

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Resting membrane potential

The electrical charge difference across the membrane of a neuron when it's not actively transmitting signals. Typically around -70 mV.

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Threshold level

The minimum level of depolarization required to trigger an action potential.

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All-or-none rule

An action potential either fires completely or not at all. Its size always remains the same regardless of the strength of the stimulus.

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Study Notes

Human Physiology Lecture Notes

  • Human physiology studies organ systems, their functions, and health maintenance.
  • Biological function is the study of how basic organ systems work.
  • Function is determined by structure.

Tissues

  • Cells with similar functions are classified into tissues.
  • Tissues are formed by similar cells bounded by a non-living matrix.
  • The matrix composition varies between tissues (e.g., liquid, semi-solid, or solid).
  • Examples: Blood (liquid matrix), bone (solid matrix).
  • Four major tissue types in the human body: muscle, nervous, epithelial, and connective.

Muscle Tissue

  • Specialized for contraction and movement.
  • Muscle contraction requires sufficient blood supply for oxygen, calcium, nutrients, and waste removal.
  • Three types of muscle tissue: skeletal, cardiac, and smooth.

Skeletal Muscle

  • Forms muscles that move bones.
  • Striated (striped) under a microscope.
  • Voluntary muscle—consciously controlled.
  • Can also contract via reflexes.
  • Arranged in bundles.
  • Contracted by motor nerve impulses originating in the brain/spinal cord.

Cardiac Muscle

  • Found only in the heart wall.
  • Responsible for heart beat.
  • Involuntary muscle—not under conscious control.
  • Striated under a microscope.
  • Interconnected cells (myocardial cells)
  • Contract as a unit.

Smooth Muscle

  • Non-striated.
  • Involuntary muscle found in the walls of hollow organs (e.g., stomach, blood vessels, reproductive systems).
  • Responsible for constricting cavities to move fluids/food.
  • Spindle-shaped cells with a single central nucleus.
  • Slower, sustained contraction than skeletal muscle.

Nervous Tissue

  • Groups of cells in the nervous system.
  • Two categories:
    • Excitable cells (neurons): initiate, receive, conduct, and transmit information. Conduct nerve impulses.
    • Non-excitable cells (glial cells): support neurons.

Epithelial Tissue

  • Forms membranes covering and lining body surfaces and glands.
  • Two types:
    • Covering and lining epithelium
      • Found on all surfaces (skin), covering organs, lining blood vessels, and heart
    • Glandular epithelium
      • Includes sweat glands, salivary glands, linings of the respiratory/intestinal tracts, and mammary glands.

Types of Simple Epithelium

  • Simple squamous epithelium consists of single flattened cells; lines the lungs, heart, blood/lymph vessels; allows for diffusion and filtration.
  • Simple cuboidal epithelium contains cube-shaped cells, lines kidney tubules, and salivary ducts; functions in secretion or absorption.
  • Simple columnar epithelium consists of column-shaped cells; lines the stomach, intestines, and urethras; also found in gallbladder and gland ducts; secretes mucous or absorbs mucous depending on location.
  • Simple ciliated columnar epithelium consists of column-shaped cells with cilia; lines the bronchi, uterine tubes; moves mucus, foreign matter, and particles.

Stratified Epithelial Tissue

  • Stratified squamous lines/covers skin/mouth; stratified cuboidal in some glands.
  • Glands (exocrine and endocrine) are derived from epithelial membranes.
  • Exocrine glands secrete through ducts onto surfaces (e.g. tears, sweat, digestive tract).
  • Endocrine glands secrete into capillaries (e.g., hormones from the pituitary).

Connective Tissue

  • Found everywhere in the body.
  • Supports and connects tissues/organs.
  • Eight types: areolar (loose connective), cartilage, bone, blood, adipose, lymphoid, yellow elastic, and white fibrous.
  • Connective tissue proper (fibrous) binds tissues, supporting epithelia, and surrounding blood vessels/nerves.
  • Specialized connective tissues include cartilage (solid), bone (mineralized/hardened), blood (fluid), and adipose tissue (fat storage).

Major Organ Systems in the Human Body

  • Integumentary, Skeletal, Muscular, Nervous, Endocrine, Digestive, Lymphatic/Immune, Circulatory, Respiratory, and Urinary.

Homeostasis Principles

  • Internal environment constant/stable for optimal cellular metabolic function.
  • Internal environment (composition) tightly controlled (physical/chemical factors regulated).
  • Achieved through muscles and glands regulated by sensory information from the internal environment.
  • Essential for life.

Homeostatic Factors: Principles

  • Set point (internal environment optimal level)

  • Detector (sensitive to changes; internal/external)

  • Control center (analyzes/processes sensor input);

  • Effector (response; counteract change until set point achieved)

  • Mechanisms control physical/chemical factors (e.g. temperature, pH, oxygen, nutrients).

Body Fluids

  • Water constitutes 60%(Males), 50%(Females) of body weight.
  • Two fluid compartments: intracellular (fluid inside cells--accounts for 2/3 body water) and extracellular (fluid outside cells; divided further into interstitial, plasma, lymph, cerebrospinal fluid).
  • Intracellular fluid: fluid within cells, two thirds of total body water; contains high levels of potassium, phosphate, and proteins.
  • Extracellular fluid: fluid outside cells—interstitial fluid, plasma, lymph, cerebrospinal fluid and milk; provides and maintains a stable internal environment; supports transportation of substances throughout the body; transfers nutrients and wastes.

Maintaining Constant Body Temperature (Thermoregulation)

  • Receptors monitor internal/external conditions (skin, brain, internal organs).
  • Control center: analyzes data, sends signals.
  • Effectors mediate response (blood vessels divert blood to skin, sweat glands; muscles generate heat via shivering).

Homeostatic Mechanisms (Negative Feedback)

  • Body reverses changes (e.g., rise in body temp.) via sweating/blood vessel dilation to reduce heat loss.
  • Maintaining homeostasis restores the body to a normal set-point

Homeostatic Mechanisms (Positive Feedback)

  • Body increases changes (e.g., blood clotting, childbirth).
  • A change in the body that increases the magnitude of the change; less frequent than negative feedback.

Signal Transmission

  • Nervous/endocrine systems work together to maintain homeostasis.
  • Nervous system: rapid response via electrical impulses.
  • Endocrine system: long-term adjustments via chemical messengers (hormones).

Summary of Homeostasis

  • Ability to maintain optimum internal conditions reduces dependence on external environment; internal environment primarily controlled by body fluids; maintained via positive & negative feedback mechanisms.

Bone Structure and Function overview

  • Bone is composed of compact & spongy bone.
  • Supports soft tissues; maintains body shape.
  • Protects internal organs (brain, heart, lungs).
  • Site of skeletal muscle attachment.
  • Stores calcium and phosphorus.
  • Forms blood cells in the marrow.

Bone Types overview

  • Long bones (levers), short bones (support), flat bones (muscle attachment/organ protection), irregular bones (internal organ protection), sesamoid bones (tendon support).

Long Bone Structure overview

  • Diaphysis: shaft; contains yellow marrow
  • Epiphysis: end; contains red marrow.
  • Articular cartilage covers part of epiphysis.
  • Periosteum covers bone surface (protects, nourishes bone tissue).

Short Bone Function overview

  • Provide stability/support; limited motion, including carpals of wrists and tarsals of ankles.

Flat Bone Function overview

  • Attachment point for muscles; protection of internal organs, particularly in the cranium, sternum, scapulae.

Irregular Bone Function overview

  • Complex shape; protect internal organs; examples include vertebrae & facial bones.

Sesamoid Bone Function overview

  • Located in tendons; protect tendons from compressive forces (e.g., patella).

Bone Marrow Function overview

  • Yellow marrow stores fat; red marrow forms blood cells.

Bone Remodeling overview

  • Continuous process involving osteoblasts (bone formation); osteoclasts (bone resorption).
  • Occurs due to mechanical stress (e.g., exercise).
  • Maintains homeostasis of calcium ion concentration, which is critical.

Osteoporosis: Clinical Connection

  • Condition characterized by bone resorption faster than formation.
  • Bones become weak; prone to fractures.
  • Elderly and postmenopausal women at increased risk.
  • Prevention includes dietary calcium, Vitamin D intake, weight-bearing exercise to stimulate osteoblasts.

Calcitonin

  • Hormone produced by thyroid gland.
  • Regulates blood calcium/phosphate levels; inhibits osteoclast activity.
  • Helps remove calcium from blood & deposit into bone.

Skeletal and Muscle Tissue overview

  • Explain general functions.
  • Describe the characteristics of the three major types of muscle tissue.
  • Explain the structure of skeletal muscle (s.m.)
    • myofibrils, and actin/myosin (myofilaments)
    • sarcomere, and band structures
  • Explain contraction steps.
  • Differentiate between Isotonic and Isometric contractions.
  • Explain how exercise affects muscles (aerobic/resistance).
  • Key clinical applications (e.g., tetanus).

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Description

Test your knowledge on the four major types of tissues in the human body, particularly muscle, connective, and epithelial tissues. This quiz covers their functions, characteristics, and interactions within the body, along with some facts about body composition and fluid compartments.

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