Human Reproductive System Quiz
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Questions and Answers

How does the morula gain nutrition before implantation?

The morula receives nutrition through diffusion from the uterine fluid.

Explain the importance of capacitation in the process of fertilization.

Capacitation is the final maturation step of the sperm. It involves changes to the sperm's membrane, making it capable of binding to the zona pellucida of the oocyte.

Describe the role of human chorionic gonadotrophin in pregnancy.

Human chorionic gonadotrophin (hCG) is a hormone produced by the developing embryo. It maintains the corpus luteum in the ovary, which continues to secrete progesterone to support the pregnancy.

Placenta previa is a medical condition occurring during pregnancy where the placenta is:

<p>Located too low in the uterus occluding the cervix (B)</p> Signup and view all the answers

The umbilical cord carries which vessels?

<p>3; 1 vein and 2 arteries (A)</p> Signup and view all the answers

The most common site of implantation in ectopic pregnancy is:

<p>Implantation in the ampulla (B)</p> Signup and view all the answers

What is the function of the acrosome?

<p>The acrosome contains enzymes, such as hyaluronidase and acrosin, that help the sperm penetrate the corona radiata and zona pellucida of the oocyte.</p> Signup and view all the answers

Which is the correct order of events in the slow block to polyspermy?

<p>Efflux of Ca2+ from smooth ER -&gt; fusion of lysosomes with oocyte membrane -&gt; hydrolytic enzymes break down zone pellucida and ZP3 receptors -&gt; entry of male pronucleus (B)</p> Signup and view all the answers

Which of the following have a 9 + 2 arrangement of microtubules?

<p>Centriole and flagella (A), Cilia and flagella (C)</p> Signup and view all the answers

Where is the corona radiata derived from?

<p>Graafian follicle (C)</p> Signup and view all the answers

What do the outer and inner cell masses of the blastocyst become?

<p>Embryoblast and trophoblast (C)</p> Signup and view all the answers

In organogenesis, which organs develop earliest?

<p>Nervous system, heart, and eyes (B)</p> Signup and view all the answers

The fast block to polyspermy is caused by:

<p>Release of Ca²+ from the smooth endoplasmic reticulum activating lysosomes (A)</p> Signup and view all the answers

Which of the following are teratogens?

<p>Vitamin A, radiation, nicotine, cocaine (A), Vitamin C, herpes virus, thalidomide, and cocaine (B)</p> Signup and view all the answers

What do elevated levels of oestrogen in maternal blood cause in preparation for labour?

<p>Increased sensitivity of smooth muscle in the uterus to oxytocin and antagonise the inhibitory effect of progesterone (D)</p> Signup and view all the answers

Why should mother and baby's blood not mix?

<p>Options 1 and 2 (B)</p> Signup and view all the answers

Flashcards

Morula Nutrition

The morula, a solid ball of cells, receives nutrients through diffusion from the surrounding fluids in the oviduct.

Capacitation Importance

Capacitation is a process that allows the sperm to be ready for fertilization. It involves changes to the sperm's surface, including the removal of a protective coating and changes in the membrane that enable the sperm to bind to the egg.

hCG Function

Human chorionic gonadotropin (hCG) is a hormone produced by the developing placenta. It maintains the corpus luteum, ensuring a continued production of progesterone, which is crucial for sustaining the pregnancy in the early stages.

Placenta Previa

Placenta previa is a condition where the placenta is located low in the uterus, partially or completely covering the cervix.

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Umbilical Cord Vessels

The umbilical cord contains two arteries and one vein.

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Ectopic Pregnancy Site

The most common site for ectopic pregnancy is the ampulla, the widest part of the fallopian tube.

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Acrosome Function

The acrosome is a cap-like structure at the head of the sperm. It contains enzymes such as hyaluronidase and acrosin, which are essential for breaking down the layers surrounding the egg (corona radiata and zona pellucida).

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Slow Block to Polyspermy

The slow block to polyspermy involves a series of events that occur in the egg after fertilization. It begins with the entry of the sperm, followed by calcium release from the smooth endoplasmic reticulum, leading to fusion of lysosomes with the oocyte membrane. Hydrolytic enzymes are then released, breaking down the zona pellucida and ZP3 receptors to prevent further sperm penetration.

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9 + 2 Microtubule Arrangement

Cilia and flagella have a 9 + 2 arrangement of microtubules, which are responsible for their movement.

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Corona Radiata Origin

The corona radiata is a layer of cells that surrounds the egg. It originates from the Graafian follicle, which is a mature ovarian follicle that releases the egg during ovulation.

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Blastocyst Inner and Outer Cell Masses

The outer cell mass of the blastocyst develops into the trophoblast, which will eventually form the placenta. The inner cell mass will develop into the embryoblast, which will form the embryo.

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Early Organ Development

The nervous system, heart, and eyes develop first during organogenesis.

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Umbilical Cord Blood Flow

In the umbilical cord, the arteries carry deoxygenated blood from the fetus to the placenta, while the veins carry oxygenated blood from the placenta to the fetus.

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Fast Block to Polyspermy

The fast block to polyspermy involves a rapid depolarization of the egg's membrane, caused by the release of sodium ions (Na^+) from the rough endoplasmic reticulum. This change in membrane potential prevents further sperm from binding to the egg.

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Teratogens

Teratogens are substances or agents that can cause birth defects. Examples include vitamin A, radiation, nicotine, cocaine, herpes virus, and thalidomide.

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Estrogen's Role in Labor

Elevated levels of estrogen in the mother's blood cause an increased sensitivity of the smooth muscle in the uterus to oxytocin. Estrogen also antagonizes the inhibitory effect of progesterone on uterine contractions, leading to increased uterine contractions and labor.

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Why Maternal and Fetal Blood Should Not Mix

Mixing of maternal and fetal blood can lead to several complications, including:

  1. Exchange of pathogens: This can be fatal for the fetus due to the risk of infection.

  2. Rh incompatibility: If the mother is Rh-negative and the fetus is Rh-positive, maternal antibodies can attack fetal red blood cells, leading to hemolytic disease of the newborn.

  3. ABO incompatibility: Although less severe than Rh incompatibility, it can cause mild problems such as jaundice.

Therefore, the correct answer is options 1 and 2.

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Implantation and Blastocyst Formation

A fertilized egg implants in the uterus and starts to develop into a blastocyst, which further differentiates into the embryo and placenta.

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Zona Pellucida Function

The zona pellucida is a glycoprotein layer surrounding the egg. It plays a crucial role in fertilization, ensuring that only one sperm fertilizes the egg, by acting as a barrier against additional sperm. It breaks down during implantation, allowing the blastocyst to attach to the uterine wall.

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Germ Layers

The germ layers are formed during gastrulation, a crucial stage in embryonic development. These layers are responsible for the formation of different tissues and organs in the body. The three germ layers are:

  1. Ectoderm: Forms skin, nervous system, and some other tissues.

  2. Mesoderm: Forms muscles, bones, circulatory system, excretory system, and others.

  3. Endoderm: Forms digestive system, respiratory system, liver, and pancreas.

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Cellular Differentiation

The process of differentiation is critical during embryonic development. It involves cells becoming more specialized in structure and function, giving rise to various tissues and organs. This process is regulated by a complex interplay of genetic factors and environmental cues.

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Organogenesis

Organogenesis is the process by which organs develop from the three germ layers. It is a complex and highly orchestrated process, regulated by genes and signaling molecules that work in concert to direct the development of specific tissues and organs.

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Fertilization Process

The process of fertilization begins with the sperm's journey through the female reproductive tract. It involves a series of steps that include:

  1. Capacitation: The sperm undergoes changes in its membrane to become capable of fertilizing the egg.

  2. Acrosome Reaction: The acrosome releases enzymes that break down the layers surrounding the egg.

  3. Penetration of the Egg: The sperm's head penetrates the outermost layer (corona radiata) and then the zona pellucida.

  4. Fusion of Gametes: The sperm's nucleus fuses with the egg's nucleus, creating a zygote.

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Study Notes

Short Answer Questions

  • Morula nutrition before implantation: Morula gains nutrition before implantation by absorbing nutrients from the uterine secretions.

  • Capacitation in fertilization: Capacitation is a process that prepares sperm for fertilization. It involves changes in sperm membrane structure enabling them to penetrate the ovum.

  • Role of human chorionic gonadotropin (hCG) in pregnancy: hCG is a hormone produced by the developing placenta. Crucially, it maintains the corpus luteum, which produces progesterone, essential for maintaining the pregnancy.

Multiple Choice Questions (MCQs)

  • Placenta previa: Placenta previa is a condition where the placenta is positioned abnormally low in the uterus, potentially blocking the cervix.

  • Umbilical cord vessels: The umbilical cord contains two arteries and one vein. These vessels transport blood between the fetus and the placenta.

  • Ectopic pregnancy implantation sites: The most common site of ectopic pregnancy implantation is the ampulla (a part of the fallopian tube).

  • Acrosome function: The acrosome, a vesicle at the head of the sperm, contains enzymes like hyaluronidase and acrosin. These enzymes are vital for digesting the corona radiata and zona pellucida, allowing sperm penetration of the ovum.

  • Events in the slow block to polyspermy: Specific events are provided in the provided text.

Additional Concepts

  • 9 + 2 arrangement of microtubules: Cilia and flagella exhibit a 9 + 2 arrangement of microtubules.

  • Corona radiata origin: The corona radiata originates from the ovarian follicle.

  • Blastocyst cell mass differentiation: The outer cell mass of a blastocyst differentiates into the trophoblast, while the inner cell mass becomes the embryoblast.

  • Early organ development (organogenesis): The nervous system and heart, among other organs, develop during early stages of organogenesis.

  • Umbilical cord blood direction: Veins in umbilical cord carry oxygenated blood from placenta to fetus; arteries carry deoxygenated blood from fetus to the placenta.

  • Fast block to polyspermy: The fast block to polyspermy results from an influx of Na⁺ ions, causing membrane depolarization, thereby preventing additional sperm from fertilizing the egg. (specific mechanism provided in the text)

  • Teratogens: Chemical and environmental factors (specifically mentioned in the provided text) such as certain vitamins, drugs, and toxins can be harmful to a developing fetus.

  • Maternal estrogen and labor preparation: Elevated levels of estrogen decrease the sensitivity of the uterine smooth muscle to oxytocin, thereby antagonizing the inhibitory effects of progesterone.

  • Why maternal and fetal blood should not mix: Mixing of maternal and fetal blood could lead to immune reactions from antibodies, potentially harming the fetus. Risk is associated with incompatibility of blood groups

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Test your knowledge on vital concepts related to the human reproductive system, including fertilization, pregnancy, and placenta conditions. This quiz covers essential topics like morula nutrition, capacitation, and important hormones in pregnancy. Perfect for students studying biology or medicine.

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