Guyton  Chapter 1

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Questions and Answers

What is primarily studied in human physiology?

  • The evolution of living organisms
  • The functions of living organisms and their parts (correct)
  • The genetic makeup of human beings
  • The interactions between different species

Which of the following best describes the relationship between the functions of individual cells and the overall function of the human body?

  • The overall function is intricately coordinated and more complex than individual cell functions (correct)
  • The overall function is less complex than individual cell functions
  • The overall function is a direct sum of individual cell functions
  • Individual cell functions are independent of the overall function

What is a distinguishing feature of physiology in understanding the human body?

  • Focusing solely on molecular function
  • Disregarding the interaction between organs
  • Examining only the skeletal system
  • Integrating the functions of the body's components (correct)

How many cells does the human body approximately contain?

<p>100 trillion (B)</p> Signup and view all the answers

What role do regulatory systems play in the body?

<p>They coordinate the functions of cells, tissues, and organs (C)</p> Signup and view all the answers

Which of the following is NOT a characteristic of cells mentioned in the content?

<p>All cells are identical in function (A)</p> Signup and view all the answers

What is the significance of integrating the functions of body parts in physiology?

<p>To understand the total function of the human body (C)</p> Signup and view all the answers

Which system is NOT typically included as a focus of human physiology?

<p>Ecosystem interaction (D)</p> Signup and view all the answers

What is the primary process by which ADP is converted back to ATP in the mitochondria?

<p>Oxidative phosphorylation (C)</p> Signup and view all the answers

What role does acetyl-CoA play in cellular respiration?

<p>It enters the citric acid cycle for energy production (B)</p> Signup and view all the answers

What is the consequence of removing an electron from a hydrogen atom during ATP formation?

<p>It creates a hydrogen ion (D)</p> Signup and view all the answers

Which component is essential for the final conversion of ADP to ATP in the mitochondrial membrane?

<p>ATP synthetase (A)</p> Signup and view all the answers

In which part of the cell does glycolysis occur, and what is its significance in ATP production?

<p>Cytoplasm; it converts glucose to pyruvic acid (D)</p> Signup and view all the answers

What property of the lipid bilayer allows it to act as a barrier to water-soluble substances?

<p>It contains hydrophilic and hydrophobic regions. (C)</p> Signup and view all the answers

Which type of membrane protein primarily provides channels for the diffusion of water-soluble substances?

<p>Integral proteins (D)</p> Signup and view all the answers

What role do glycoproteins play in the cell membrane?

<p>They are involved in cell recognition and signaling. (C)</p> Signup and view all the answers

How do phospholipids contribute to the structure of the cell membrane?

<p>They create a bilayer with hydrophilic and hydrophobic regions. (D)</p> Signup and view all the answers

Which of the following statements accurately describes peripheral proteins in the membrane?

<p>They are tightly bound to the membrane and do not penetrate. (C)</p> Signup and view all the answers

What characteristic of the cell membrane contributes to its selective permeability?

<p>The structure of the lipid bilayer with embedded proteins. (B)</p> Signup and view all the answers

How do integral proteins function in substance transport across the cell membrane?

<p>They can transport substances with and against their gradients. (A)</p> Signup and view all the answers

Which of the following describes the arrangement of phospholipids in the lipid bilayer?

<p>Hydrophobic portions face each other, while hydrophilic parts face outward. (B)</p> Signup and view all the answers

What is the primary function of receptors on integral proteins?

<p>To bind and respond to specific extracellular signals. (C)</p> Signup and view all the answers

What is the effect of the cell membrane's lipid composition on the movement of oxygen and carbon dioxide?

<p>It freely allows the movement of these gases due to their lipid solubility. (B)</p> Signup and view all the answers

Which organ is primarily responsible for modifying absorbed substances into more usable forms?

<p>Liver (C)</p> Signup and view all the answers

What primary role do peripheral proteins play in the cell membrane?

<p>Catalyze chemical reactions (C)</p> Signup and view all the answers

What is one of the primary functions of the musculoskeletal system?

<p>Protecting internal organs (C)</p> Signup and view all the answers

What components are most commonly combined with carbohydrates in the cell membrane?

<p>Proteins and lipids (C)</p> Signup and view all the answers

How do the kidneys contribute to maintaining blood pressure?

<p>By controlling excretion of salts and water (B)</p> Signup and view all the answers

What is the term used to describe the loose carbohydrate coat on the outer surface of cells?

<p>Glycocalyx (B)</p> Signup and view all the answers

Which system is involved in the removal of carbon dioxide from the body?

<p>Respiratory system (B)</p> Signup and view all the answers

Which of the following is NOT a function of the carbohydrates located on the outer cell surface?

<p>Transporting ions across the membrane (A)</p> Signup and view all the answers

What role do fat cells play in relation to absorbed substances?

<p>Storing absorbed substances (A)</p> Signup and view all the answers

What primary materials are synthesized by the Endoplasmic Reticulum?

<p>Proteins, carbohydrates, and lipids (C)</p> Signup and view all the answers

Which system directs the activity of the muscular system?

<p>Nervous system (C)</p> Signup and view all the answers

What is primarily excreted by the kidneys?

<p>Waste products and salts (A)</p> Signup and view all the answers

In which part of the Endoplasmic Reticulum do ribosomes attach to synthesize proteins?

<p>Granular ER (D)</p> Signup and view all the answers

What role does the Golgi apparatus play after proteins are synthesized in the ER?

<p>Modifying and packaging proteins (B)</p> Signup and view all the answers

Which system allows the body to sense its environment?

<p>Nervous system (D)</p> Signup and view all the answers

What function does the liver have in relation to toxic substances?

<p>Eliminates certain wastes and toxins (D)</p> Signup and view all the answers

What are proteoglycans primarily made of?

<p>Carbohydrates bound to protein cores (D)</p> Signup and view all the answers

How do negatively charged carbohydrates on cell surfaces predominantly interact with other molecules?

<p>They repel other negatively charged molecules (C)</p> Signup and view all the answers

What is a function of cartilage in the musculoskeletal system?

<p>Protect joints and provide cushioning (C)</p> Signup and view all the answers

What substances are produced by the Endoplasmic Reticulum that are essential for cell function?

<p>Proteins, carbohydrates, lipids, and organelles (A)</p> Signup and view all the answers

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Study Notes

Physiology Overview

  • Physiology studies the functions of living organisms and their parts.
  • Human physiology examines characteristics that enable survival and interaction with the environment.
  • It integrates functions of cells, tissues, organs, and organ systems to understand the whole body.

Cells as Living Units

  • The human body comprises approximately 100 trillion cells, each adapted for specific functions.
  • Different cell types, such as liver cells, modify absorbed substances while others store materials and manage waste.

Musculoskeletal System

  • Composed of skeletal muscles, bones, tendons, joints, cartilage, and ligaments.
  • Essential for movement, organ protection, and body support.

Removal of Metabolic End Products

  • The respiratory system provides oxygen and removes carbon dioxide from the blood.
  • Kidneys excrete waste products and regulate extracellular fluid composition, impacting blood volume and pressure.
  • The liver detoxifies substances and eliminates metabolic waste.

Regulation of Body Functions

  • The nervous system influences muscular activity and organ function via the autonomic nervous system.
  • Helps in environmental sensing and enhancing survival conditions.

Cell Membrane Structure

  • Composed mainly of a lipid bilayer containing phospholipids, sphingolipids, and cholesterol.
  • The bilayer acts as a barrier to water-soluble substances while allowing lipid-soluble substances to pass.

Membrane Proteins

  • Integral proteins span the membrane, creating channels for ions and serving as carriers.
  • Peripheral proteins typically function as enzymes and are attached to integral proteins.

Glycocalyx

  • A carbohydrate coat on the cell's outer surface consisting of glycoproteins and glycolipids.
  • Functions include repelling negatively charged molecules, aiding cell attachment, and serving as hormone receptors.

Endoplasmic Reticulum (ER)

  • A network of tubules and vesicles synthesizing proteins, carbohydrates, and lipids.
  • Ribosomes on the granular ER synthesize proteins that enter the Golgi apparatus for modification.

ATP Production

  • Most ATP is produced in mitochondria through processes involving glycolysis, citric acid cycle, and oxidative phosphorylation.
  • The conversion of pyruvic acid to acetyl-CoA initiates the Krebs cycle, leading to substantial ATP production via the transfer of hydrogen ions to oxygen.

Energy Conversion

  • ATP synthetase in mitochondria uses energy from hydrogen ions moving across membranes to convert ADP into ATP, with water formed as a byproduct.

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