Human Physiology and Diseases
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Questions and Answers

What is the primary method of heat loss in humans when the skin temperature is higher than the environment?

  • Evaporation
  • Radiation (correct)
  • Convection
  • Conduction
  • Which amino acid is considered the 21st amino acid?

  • Pyrrolysine
  • Lysine
  • Cysteine
  • Selenocysteine (correct)
  • What is the substitution in the beta-chain of hemoglobin that leads to sickle cell disease?

  • Valine → Glutamate (correct)
  • Lysine → Glutamate
  • Glutamate → Valine
  • Glutamate → Lysine
  • Which type of collagen fiber is defective in the condition characterized by bilateral hearing loss and lens opacification?

    <p>Type IV collagen fiber</p> Signup and view all the answers

    What is the primary transporter involved in insulin-stimulated glucose uptake?

    <p>GLUT4</p> Signup and view all the answers

    What is the acceptable macronutrient distribution range (AMDR) of simple sugars?

    <p>10% of total daily energy intake</p> Signup and view all the answers

    Study Notes

    Heat Loss in Humans

    • When skin temperature is greater than the environment temperature, radiation is the major mode of heat loss.

    Amino Acids

    • Selenocysteine is determined as the 21st amino acid.

    Sickle Cell Disease

    • Sickle cell disease results from a missense mutation in both genes encoding for the beta-chain, resulting in a change from Glutamate to Valine.

    Collagen Fiber Defects

    • Defects in Type IV collagen fiber are associated with a condition causing gross hematuria, elevated blood pressure, and decreased urine output, accompanied by bilateral hearing loss and opacification of the lenses.

    Glucose Uptake

    • Insulin-stimulated glucose uptake involves the GLUT4 transporter.

    Macronutrient Distribution

    • The acceptable macronutrient distribution range (AMDR) of simple sugars is not specified, but the exact range is an important concept in nutrition.

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    Description

    This quiz covers various topics in human physiology and diseases, including heat loss, amino acids, sickle cell disease, and collagen fiber defects.

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